Navigation Links
Exposure to stress even before conception causes genetic changes to offspring
Date:7/8/2013

A female's exposure to distress even before she conceives causes changes in the expression of a gene linked to the stress mechanism in the body in the ovum and later in the brains of the offspring from when they are born, according to a new study on rats conducted by the University of Haifa.

"The systemic similarity in many instances between us and mice raises questions about the transgenerational influences in humans as well, for example, the effects of the Second Lebanon War or the security situation in the South on the children of those who went through those difficult experiences," the researchers said. "If until now we saw evidence only of behavioral effects, now we've found proof of effects at the genetic level."

In previous studies in Prof. Micah Leshem's lab, it was found that exposing rats to stress before they had even conceived (and even at their "teen" stage) influences the behavior of their offspring. This study, conducted in the lab of Dr. Inna Gaisler-Salomon by PhD student Hiba Zaidan, in cooperation with Prof. Leshem, the researchers sought to examine whether there was an influence on genetic expression.

In the study, which was recently published in the journal Biological Psychiatry, the researchers focused on the gene known as CRF-1, a gene linked to the body's stress-control system that expresses itself in many places in the brain under stress.

The researchers took female rats that were 45 days old, which is parallel to human adolescence. Some of the rats were exposed to "minor" stress, which included changes in temperature and daily routine for seven days, and compared them to a control group that was not exposed to stress at all. The rats were mated and conceived two weeks later.

In the first part of the study, the researchers examined the ova of the rats that were exposed to stress even before they conceived, and they found that at that stage there was enhanced expression of the CRF-1 gene. For the second part,
'/>"/>

Contact: Polina Petruhin
ppetruh1@univ.haifa.ac.il
972-543-933-092
University of Haifa
Source:Eurekalert

Page: 1 2

Related medicine news :

1. C8 Lawsuit Lawyers at Wright & Schulte LLC Report on Growing Litigation Over Exposure to C8 Tainted Drinking Water from DuPont’s Washington Works Plant
2. Virginia Surgeon Dr. Mark W. McFarland Uses SpineFrontier’s Less Exposure Surgery Technologies: the New Invue Inset Trial-Cage Drill Guide and the Low-Profile Invue Inset
3. C8 Lawsuit News: Wright & Schulte LLC Launches C8 Facebook Page to Provide Up-to-Date Information On C8 Exposure and C8 Lawsuits in Ohio and West Virginia
4. Exposure to BPA in developing prostate increases risk of later cancer
5. Exposure to low doses of BPA linked to increased risk of prostate cancer in human stem cells
6. Cutting-Edge 3-D Technology at Midtown Dentistry Reduces Patient X-Ray Exposure
7. TCE exposure linked to increased risk of some cancers
8. Pesticide Exposure May Raise Parkinsons Risk, Study Suggests
9. Hidden Beach, the Only Luxurious All-inclusive Nudist Resort in the Mexican Caribbean, to Host Social Exposure's Naked Painting Party, Announces Go Classy Tours
10. Exposure to Secondhand Smoke May Lead to Worsening of Pediatric Kidney Disease; Pediatric Nephrology Publishes Dayton Children’s, Johns Hopkins Joint Study
11. Early-life traffic-related air pollution exposure linked to hyperactivity
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/31/2014)... Oct. 31, 2014 (HealthDay News) -- Access to generic ... patients will stick with their drug treatment, a new ... women with hormone receptor-positive breast cancer can reduce recurrence ... Hershman, an associate professor of epidemiology at Columbia University ... hospital news release. "However, work by our ...
(Date:10/31/2014)... Alan Mozes HealthDay ... In the world of 21st-century medicine, organ transplantation is nothing ... followed by the first liver transplant in 1963 and the ... even managed the transplantation of a patient,s entire face. ... entire human eye. But if one team of U.S. scientists ...
(Date:10/31/2014)... Each year, people across the United States spend an ... friends, which costs $522 billion, according to new research. ... on the time and wages that caregivers give up ... in daily activities. The study authors said the significant ... workplace flexibility policies. "Our findings provide a new ...
(Date:10/30/2014)... at Albert Einstein College of Medicine ... will present their latest aging research at ... Scientific Meeting. Topics include the identification of a ... cognitive impairment and the cellular biology of aging. ... in Washington, D.C., "Einstein-Montefiore has distinguished itself in ...
(Date:10/30/2014)... Tanaka and her research group at the DFG Research ... at the TU Dresden (CRTD) demonstrated for the first ... spinal cord in three dimensions from mouse embryonic stem ... dorsal interneurons along the dorsal/ventral axis was observed., This ... " Stem Cell Reports " on 30.10.2014 ., ...
Breaking Medicine News(10 mins):Health News:Generic Drugs May Help Breast Cancer Patients Stick to Therapy 2Health News:Scientists Set Their Sights on First Whole-Eye Transplant 2Health News:Scientists Set Their Sights on First Whole-Eye Transplant 3Health News:'Informal Care' for Older Americans Tops $500B Annually, Study Finds 2Health News:Einstein-Montefiore investigators present aging research at Gerontological Society of America's Annual Scientific Meeting 2Health News:Einstein-Montefiore investigators present aging research at Gerontological Society of America's Annual Scientific Meeting 3Health News:Einstein-Montefiore investigators present aging research at Gerontological Society of America's Annual Scientific Meeting 4Health News:Reconstruction of a patterned piece of spinal cord in 3-D culture 2
... 30 Keck Graduate Institute (KGI) ... begin in January 2010, for those with an undergraduate degree ... skills before applying to medical school. , "We,re excited to ... medical professional," says Sheldon M. Schuster, PhD, KGI,s president. "Whether ...
... BEIJING, Sept. 30 /PRNewswire-Asia/ -- Sinovac Biotech ... products in China, announced today that,Sinovac has received its ... Ministry of Industry and Information Technology of the People,s,Republic ... purchase order,Sinovac is required to produce an additional 3 ...
... America, Inc. (OTC Bulletin Board: CBAI), the umbilical cord ... ) focused on bringing the life saving potential ... nationwide and internationally, said today that it is opening ... laboratory in Las Vegas, as planned, the first ...
... National Breast Cancer Awareness Month and Topcor is introducing a ... October 5th, "Clipa for a Cure" is a special edition ... donate 10% of the retail price of every pink Clipa ... Society, breast cancer is the second leading cause of cancer ...
... Americans lack confidence that healthcare reform will deliver ... a survey released today by Thomson Reuters. , Forty-one ... make healthcare more affordable. When sorted by political ... divisions along party lines: 72 percent of Democrats said ...
... , LUDWIGSHAFEN, Germany, September 30 ... to cope with all the sustenance,we shove into it every ... the hardest substance that the human body produces. It consists ... questions of our Podcast listeners on Chemistry in our,everyday life. ...
Cached Medicine News:Health News:KGI Establishes Post Baccalaureate Premedical Program 2Health News:Sinovac Obtains Second Order of H1N1 Vaccine from Chinese Central Government 2Health News:Sinovac Obtains Second Order of H1N1 Vaccine from Chinese Central Government 3Health News:Cord Blood America Opens Las Vegas Cryogenic Laboratory; Consolidates Offices in Nevada 2Health News:Cord Blood America Opens Las Vegas Cryogenic Laboratory; Consolidates Offices in Nevada 3Health News:'Clipa for a Cure': New Pink Instant Handbag Hanger Benefits Breast Cancer Research 2Health News:Thomson Reuters Survey: Americans Skeptical That Healthcare Reform Will Improve Quality or Affordability 2Health News:BASF Podcast: The Chemical Reporter - Why Does Fluoride Make Your Teeth Hard? 2Health News:BASF Podcast: The Chemical Reporter - Why Does Fluoride Make Your Teeth Hard? 3
(Date:10/31/2014)...  Zebra Imaging, Inc., the world,s foremost provider ... strategic partnership with the Zygote Media Group Inc., ... biomedical models for animation and visual effects, to ... maintains the world,s most comprehensive library of accurate ... development of high-end solid 3D anatomy models for ...
(Date:10/31/2014)... October 31, 2014 Oramed ... pharmaceutical company focused on the development of oral ... host a conference call to discuss the clinical ... ORMD-0801, the company,s proprietary oral insulin capsules, to ... 2014 at 10:00 a.m. Eastern time. ...
(Date:10/31/2014)... 2014  Zacks.com announces the list of stocks featured in the ... latest news and events impacting stocks and the financial markets. Stocks ... - Free Report ), Celgene (Nasdaq: CELG ... - Free Report ), Market Vectors Biotech ETF (AMEX: ... (AMEX: XBI - Free Report ). ...
Breaking Medicine Technology:Zebra Imaging and Zygote Media Partner to Bring 3D Visualization to the Medical Community 2Oramed to Report Key Top Line Results from U.S. Phase IIa Trial with Oral Insulin in Type 1 Diabetes 2Oramed to Report Key Top Line Results from U.S. Phase IIa Trial with Oral Insulin in Type 1 Diabetes 3The Zacks Analyst Blog Highlights: Amgen, Celgene, Biogen Idec, Market Vectors Biotech ETF and SPDR S&P Biotech ETF 2The Zacks Analyst Blog Highlights: Amgen, Celgene, Biogen Idec, Market Vectors Biotech ETF and SPDR S&P Biotech ETF 3The Zacks Analyst Blog Highlights: Amgen, Celgene, Biogen Idec, Market Vectors Biotech ETF and SPDR S&P Biotech ETF 4The Zacks Analyst Blog Highlights: Amgen, Celgene, Biogen Idec, Market Vectors Biotech ETF and SPDR S&P Biotech ETF 5The Zacks Analyst Blog Highlights: Amgen, Celgene, Biogen Idec, Market Vectors Biotech ETF and SPDR S&P Biotech ETF 6The Zacks Analyst Blog Highlights: Amgen, Celgene, Biogen Idec, Market Vectors Biotech ETF and SPDR S&P Biotech ETF 7
... Knopp Neurosciences Inc. ("Knopp"),today announced the ... of KNS-760704, a,small molecule therapy in development ... (Logo: http://www.newscom.com/cgi-bin/prnh/20070924/KNOPPLOGO ) ... in healthy volunteers is being closely followed ...
... planning,use prevents over one million HIV-positive births worldwide ... the number of infants born with HIV,according to ... for Women With HIV," published by the INFO ... Center for Communication Programs. Women account for ...
Cached Medicine Technology:Knopp Neurosciences Initiates Phase 1 Clinical Trial of KNS-760704 in ALS Development Program 2Knopp Neurosciences Initiates Phase 1 Clinical Trial of KNS-760704 in ALS Development Program 3Hopkins Report: Focusing on Family Planning Lessens HIV Impact 2Hopkins Report: Focusing on Family Planning Lessens HIV Impact 3
This cannula's patented tip allows the simultaneous infusion of cardioplegia and aspiration of air from the aorta...
This cannula features a PVC body, auto inflatable smooth cuff, pressure monitoring line with integral stopcock....
...
... Select CAP® cannulae provides a simple ... readings. An innovative combination of aortic ... line, the Select CAP® can provide ... arterial pressure readings on which you ...
Medicine Products: