Navigation Links
Exposure to chemicals in environment associated with onset of early menopause
Date:3/23/2011

Chevy Chase, MD A recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM) found that higher levels of perfluorocarbons (PFCs) in the body are associated with increased odds of having experienced menopause in women between 42 and 64 years old. Women in this age group with high levels of PFCs also had significantly lower concentrations of estrogen when compared to women who had low levels of PFCs.

PFCs are man-made chemicals used in a variety of household products including food containers, clothing, furniture, carpets and paints. Their broad use has resulted in widespread dissemination in water, air, soil, plant life, animals and humans, eve in remote parts of the world. A probability sample of U.S. adults, found measurable concentrations of PFCs in 98 percent of the participants tested.

"The current study is the largest ever to be done on the endocrine-disrupting effects of perfluorocarbons in human women," said Sarah Knox, PhD, of the West Virginia University School of Medicine in Morgantown and lead author of the study. "Our data shows that after controlling for age, women of perimenopausal and menopausal age in this large population are more likely to have experienced menopause if they have higher serum concentrations of PFCs than their counterparts with lower levels."

In this study of 25,957 women aged 18 to 65 years, researchers ascertained menopausal status of participants and then measured their serum concentration levels of PFCs and estradiol. They found that there was an association between PFC exposure, decreased estradiol and early menopause in women over age 42. There was also an inverse association between PFC levels and estradiol in women of child bearing age but this association was not statistically significant.

"There is no doubt that there is an association between exposure to PFCs and onset of menopause, but the causality is unclear," said Knox. "Part of the explanation could be that women in these age groups have higher PFC levels because they are no longer losing PFCs with menstrual blood anymore, but, it is still clinically disturbing because it would imply that increased PFC exposure is the natural result of menopause."

PFCs are known to have multiple adverse health outcomes including increased cardiovascular risk and impairment of the immune system.

"Our findings suggest that PFCs are associated with endocrine disruption in women and that further research on mechanisms is warranted," said Knox.


'/>"/>

Contact: Aaron Lohr
alohr@endo-society.org
240-482-1380
The Endocrine Society
Source:Eurekalert

Related medicine news :

1. Exposure to organochloride pesticides affects semen quality
2. Tanning bed exposure can be deadly when complicated by medication reactions
3. Many Dialysis Patients at Risk for High Radiation Exposure
4. Innovative virtual reality exposure therapy shows promise for returning troops
5. Lead Exposure May Raise Blood Pressure in Pregnancy
6. New study to use smart phones to track air pollution exposure
7. Prenatal Exposure to Pesticides May Harm Kids Development
8. Risk of cancer increases with exposure to low-dose radiation
9. Secondhand television exposure linked to eating disorders
10. Exposure to death and dying can have a positive impact
11. Nicotine exposure in pregnant rats puts offspring at risk for learning disabilities
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/11/2016)... ... February 11, 2016 , ... From March 4 through ... Dermatology Annual Meeting at the Walter E. Washington Convention Center in Washington, D.C. ... the condition of hyperhidrosis (excessive sweating) and its treatment options. Specifically, the company ...
(Date:2/11/2016)... Diego, CA (PRWEB) , ... February 11, 2016 , ... ... which was held in San Diego, CA, on February 6th & 7th, 2016 according ... combine for those who were not invited to the NFL’s combine in Indianapolis,” says ...
(Date:2/11/2016)... ... 11, 2016 , ... The book, “Computers Should Just Work!”, provides a basic, ... your IT consultant before signing a contract and how to spot an incompetent or ... relying heavily on e-mail and technology, it’s more important than ever to make sure ...
(Date:2/11/2016)... ... February 11, 2016 , ... As part of their 2015 end of ... Round Table Foundation (MDRTF), has gifted $10,000 to University of Chicago to support ovarian ... Billy Cundiff. , “We are honored to support a promising young investigator from Dr. ...
(Date:2/10/2016)... Culver City, California (PRWEB) , ... February 10, ... ... Molecular Imaging Society (WMIS), known as the World Molecular Imaging Congress (WMIC), will ... The theme for the 2016 meeting is “Imaging Biology…Improving Therapy.” The congress will ...
Breaking Medicine News(10 mins):
(Date:2/10/2016)...  Oxis International Inc. (OTC/QB: OXIS) announced today that ... a "clinical trial triumph" after one of the first ... remission. Daniel Vallera , a research ... --> Daniel Vallera , a research ... --> An article on the University ...
(Date:2/10/2016)... , Feb. 10, 2016  LexisNexis® Risk ... technology, today announced the launch of LexisNexis ... solution that helps improve and optimize the quality ... of performance using severity-adjusted scores. By measuring provider ... critical solution to deliver better outcomes, improve the ...
(Date:2/10/2016)... AKIVA, Israel , February 10, 2016 ... a leader in the field of cartilage repair, announces ... February 5, 2016. The $15 million investment was led ... Chinese pharmaceutical manufacturer, and was joined by existing Regentis ... Holdings and both the Technion Research & Development Foundation ...
Breaking Medicine Technology: