Navigation Links
Exposure to BPA in developing prostate increases risk of later cancer
Date:6/17/2013

Early exposure to BPA (bisphenol A) an additive commonly found in plastic water bottles and soup can liners causes an increased cancer risk in an animal model of human prostate cancer, according to University of Illinois at Chicago researcher Gail Prins. Prins presented her findings at the ENDO 2013 meeting in San Francisco June 17.

"This is the first direct evidence that exposure to BPA during development, at the levels we see in our day-to-day environment, increases the risk for prostate cancer in human prostate tissue," said Prins, professor of physiology and director of the andrology laboratory in urology at the UIC College of Medicine.

The increased risk can be traced to prostate stem and progenitor cells which become "sensitized" to estrogen early in development through exposure to BPA -- which mimics estrogen in the body. Environmental exposure to compounds like BPA that mimic hormones has become common, said Prins. Prostate stem cells, which are very long-lived, pass on the increased estrogen sensitivity to the prostate tissues they produce throughout life. Because prostate cancer is fueled in part by naturally rising estrogen levels in aging men, the prostate tissue's increased sensitivity to estrogen makes the development of cancer much more likely, according to Prins.

"Studies of expectant mothers in the U.S. showed that more than 95 percent of them had BPA in their urine, which means they recently ingested these compounds, " says Prins, whose work led to banning the sale of baby bottles and cups containing BPA in Chicago in 2009. Previous studies by Prins and colleagues using rats showed that exposure to elevated estrogen or BPA during embryonic development increased the rate of prostate cancer later in life. To determine if there was a link in humans, Prins developed a new animal model using human prostate stem cells implanted into mouse "hosts."

Prins took human prostate stem cells from deceased young adult male organ donor
'/>"/>

Contact: Sharon Parmet
sparmet@uic.edu
312-413-2695
University of Illinois at Chicago
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Antibody therapy prevents gastrointestinal damage following radiation exposure in mice
2. Genetic variants, tobacco exposure and lung cancer risk
3. Leaded Gas Exposure Linked to Later Violence: Study
4. Majority of states fail to address youth exposure to alcohol marketing
5. Prenatal exposure to pollution especially dangerous for children with asthma
6. Novel biomarkers reveal evidence of radiation exposure
7. Education May Protect Brain From Exposure to Solvents
8. Taking Anti-HIV Meds Prior to Exposure May Help Prevent Infection
9. New research showing how real-life exposure to violence disrupts a childs sleep habits
10. BPA exposure effects may last for generations
11. How MyTownInsurance.com Helps Insurance Carriers Manage their Loss Exposure through On-Line Marketing
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/1/2015)... (PRWEB) , ... September 01, ... ... seeking better therapeutic options to efficiently cure and prevent different malignancies. Some ... cancers have different pathophysiological properties due to which distinctive approach is necessary ...
(Date:9/1/2015)... ... September 01, 2015 , ... Negative pressure wound ... a wound to remove exudates, fluid, and infectious materials to prepare the wound ... devices, disposable devices, and canisters, etc.) is projected to expand continuously through 2021. ...
(Date:9/1/2015)... ... September 01, 2015 , ... The ... Information Management has been granted continued accreditation based on a successfully completed ... ÔÇťAchieving and maintaining this accreditation takes the involvement and dedication of each ...
(Date:9/1/2015)... ... September 01, 2015 , ... ... government entities, announced today that it has hired Scott Sanderson, an experienced business ... this capacity, Sanderson will be responsible for establishing and managing new client relationships ...
(Date:9/1/2015)... ... 2015 , ... WorkCare, Inc., a national occupational health services ... as an Associate Medical Director. , WorkCare specializes in workforce health protection ... abroad. , Dr. Nelson has a diverse background. He trained in sports ...
Breaking Medicine News(10 mins):Health News:CD Antigen Cancer Market and Pipeline Landscape Examined in Comprehensive Kuick Research Report Published at MarketPublishers.com 2Health News:CD Antigen Cancer Market and Pipeline Landscape Examined in Comprehensive Kuick Research Report Published at MarketPublishers.com 3Health News:World Negative Pressure Wound Therapy Market Assessed by GlobalData in In-demand Report Published at MarketPublishers.com 2Health News:World Negative Pressure Wound Therapy Market Assessed by GlobalData in In-demand Report Published at MarketPublishers.com 3Health News:Edge Information Management Granted Continued NAPBS Accreditation 2Health News:Edge Information Management Granted Continued NAPBS Accreditation 3Health News:Former NFL Standout Scott Sanderson Joins eDiscovery Leader Discovia 2Health News:Dr. Brent Nelson Joins WorkCare, Inc., as Associate Medical Director 2Health News:Dr. Brent Nelson Joins WorkCare, Inc., as Associate Medical Director 3
... Seeking Feedback on Revisions to Standards , , WASHINGTON, ... comprehensive review of its standards, URAC , ... for public comment on revisions to its Health ... Security standards . URAC welcomes purchasers, policy ...
... June 18 /PRNewswire-Asia-FirstCall/ -- Jiangbo,Pharmaceuticals Enterprises, Inc. (OTC ... company with its principal operations in the,People,s Republic ... the China New,Drugs Trade Fair from June 26 ... Exhibition Center, and also plans to launch a ...
... , DENVER, June 18 DaVita Inc. (NYSE: ... those diagnosed with chronic kidney disease (CKD), today announced the ... Work for in Colorado Program. DaVita(R) is the only ... , (Logo: http://www.newscom.com/cgi-bin/prnh/20020729/DAVITALOGO ) , , "We ...
... ... Southeast Asia,s largest private hospital and one of the world,s top medical travel destinations, ... Quality Class (TQC) award for 2008. , ... Bangkok, Thailand (PRWEB) June 18, 2009 -- Bumrungrad International ...
... ... has been validated by ACHC as an organization dedicated to quality patient services, and ... ... -- Homefront Diabetic Services proudly announces its award of accreditation status by the Accreditation ...
... approach to choosing the best treatment options for early breast ... in a report from the 11th St Gallen conference. ... Annals of Oncology [1] today (Thursday 18 June), and ... from the conference of more than 4,800 participants from 101 ...
Cached Medicine News:Health News:Public Comment Period Open for HIPAA Privacy and Security Standards 2Health News:Public Comment Period Open for HIPAA Privacy and Security Standards 3Health News:Public Comment Period Open for HIPAA Privacy and Security Standards 4Health News:Jiangbo Pharmaceuticals to Attend the 44th China New Drugs Trade Fair in Tianjin 2Health News:Jiangbo Pharmaceuticals to Attend the 44th China New Drugs Trade Fair in Tianjin 3Health News:DaVita Named One of Best Companies to Work for in Colorado 2Health News:Bumrungrad International the first private hospital to be awarded Thailand Quality Class (TQC) for organizational excellence 2Health News:Bumrungrad International the first private hospital to be awarded Thailand Quality Class (TQC) for organizational excellence 3Health News:Homefront Diabetic Services Completes Accreditation with ACHC 2Health News:St. Gallen consensus 2009: A radically different approach to treating early breast cancer 2Health News:St. Gallen consensus 2009: A radically different approach to treating early breast cancer 3
(Date:9/1/2015)... Sept. 1, 2015 Taiwan,s ... press conference in Taipei on  ... new Vaucarrin™ platform, a targeted drug delivery technology that ... This event was part of a joint press conference ... NanoTech Inc. (GNT), showcasing GNT,s latest edible gold-based food ...
(Date:9/1/2015)... 1, 2015 Agena Bioscience TM today announced ... , a commercial and financial hub from which many biotech ... testing laboratories in mainland China . ... Bioscience,s global sales with almost sixty MassARRAY ® Systems ... will allow us to expand our reach and foster ...
(Date:9/1/2015)... , 1. September 2015 In ... von 2.500 Mitarbeitern hat die SHL Group schnell ... konstantes und rapides Wachstum auf dem Markt ... die Produktivität und das Management von SHL wieder. ... SHL ist weltweit führend in Design und ...
Breaking Medicine Technology:GNTbm Updates Developments in the Vaucarrin(TM) annogold Drug Delivery Platform 2GNTbm Updates Developments in the Vaucarrin(TM) annogold Drug Delivery Platform 3GNTbm Updates Developments in the Vaucarrin(TM) annogold Drug Delivery Platform 4GNTbm Updates Developments in the Vaucarrin(TM) annogold Drug Delivery Platform 5Agena Bioscience Opens Office in Shanghai, China 2SHL Group erreicht wichtigen Markstein von 3.000 Mitarbeitern 2
... N.Y., Aug. 17, 2011 Polymedco is pleased ... Colorectal Cancer Screening in Integrated Health Care Systems" ... Burley, Juan Reyes, Michael Oehrli, and Cindy Caldwell ... screening program for Colorectal cancer (CRC) at Kaiser ...
... 17, 2011  ConvaTec, a world-leading developer and marketer ... today announced the appointments of Charles Cerminara and James ... has been appointed Vice President and General Manager, Greater ... on the growth of the Chinese market and to ...
Cached Medicine Technology:Polymedco Announces Publication in Epidemiologic Reviews 2ConvaTec Announces Asia-Pacific Leadership Appointments 2
3.2 mm Keratome, double bevel, sharp sides, ang. 1 Ea as quantity....
... the surgeon with high power performance and ... electrosurgical needs. 9000 volts peak to peak ... of pure cutting power make the Sabre ... is designed to meet the broadest range ...
LigaSure system generator, bipolar only. Designed to permanently seal vessels and tissue bundles....
Microcontroller-based isolated electrosurgical generator, designed for all general purpose surgical procedures. Unit includes: Instant Response technology, adaptive REM system, isolated output, CEM c...
Medicine Products: