Navigation Links
Exposure/ritual prevention therapy boosts antidepressant treatment of OCD
Date:9/12/2013

NIMH grantees have demonstrated that a form of behavioral therapy can augment antidepressant treatment of obsessive compulsive disorder (OCD) better than an antipsychotic. The researchers recommend that this specific form of cognitive behavior therapy (CBT) exposure and ritual prevention be offered to OCD patients who don't respond adequately to treatment with an antidepressant alone, which is often the case. Current guidelines favor augmentation with antipsychotics.

In the controlled trial with 100 antidepressant-refractory OCD patients, 80 percent of those who received CBT responded, compared to 23 percent of those who received the antipsychotic risperidone, and 15 percent of those who received placebo pills. Forty-three percent experienced symptoms reduced to a minimal level following CBT treatment, compared to 13 percent for risperidone and 5 percent for placebo.

The study, published September 11, 2013 in JAMA Psychiatry, was led by Helen Blair Simpson, M.D., of Columbia University, in New York City; and Edna Foa, Ph.D., of the University of Pennsylvania, Philadelphia.

In an accompanying editorial, grantees Kerry Ressler, M.D., and Barbara Rothbaum, Ph.D., of Emory University, Atlanta, note that antidepressants are effective in treating only a subset of OCD patients. They add that the targeted form of CBT works via different mechanisms such as retraining the brain's habit-forming circuitry to unlearn compulsive rituals.

Matthew Rudorfer, M.D., chief of the NIMH Somatic Treatments Program, which funded the study, said that in demonstrating how different patients respond best to different approaches, it helps to move the field toward the goal of more personalized treatment.


'/>"/>

Contact: Jules Asher
NIMHpress@nih.gov
301-443-4536
NIH/National Institute of Mental Health
Source:Eurekalert

Page: 1

Related medicine news :

1. Report says new evidence could tip the balance in aspirin cancer prevention care
2. Decision guide reduced uncertainty over breast cancer prevention, study finds
3. HIV Prevention Pill Cost-Effective for High-Risk Men: Study
4. Report outlines successes, challenges in cancer prevention efforts
5. Animated characters keep it real in teen violence prevention videos
6. Cyberbullying May Call for New Prevention Tactics
7. Supplements and cancer prevention: A cautionary tale
8. Better health in adulthood starts with early prevention in childhood
9. New guidelines deliver concise messages for implementing cardiovascular prevention
10. HIV prevention measures must include behavioral strategies to work, says APA
11. Researchers call for obesity prevention efforts to focus on community-wide systems
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2015)... 18, 2015 Rosetta Radiology is proud ... out their list of diagnostic imaging services. This solidifies ... on the Upper East Side of Manhattan. , The ... capacity. The addition of PET-CT, combined with Rosetta’s state ... ability to work with patients through several stages of ...
(Date:4/17/2015)... 17, 2015 Riviera Magazine ... Sadati of the Gallery of Cosmetic Surgery in ... beauty experts. The publication focused on his expertise ... cell fat grafting, eyelid surgery, laser resurfacing and rhinoplasty. ... surgery has resulted in thousands of satisfied patients ...
(Date:4/17/2015)... Florida Hospital Wesley Chapel, Florida Hospital ... Carrollwood were all selected as Top Workplaces in Tampa ... County, is ranked number one for large businesses according ... conducted in partnership with an independent research firm. Florida ... that opened in October of 2012 with a vision ...
(Date:4/17/2015)... (PRWEB) April 17, 2015 From the day ... ago, the Texas non-profit organization has empowered young people to ... effort to bring fresh water and the Gospel to ... Liberty University. Between March 17 and 27, students, faculty and ... 7,000 Liberians with fresh water and the Good News of ...
(Date:4/17/2015)... April 17, 2015 Consumers who prefer ... without modifications can now use the Insurance Pros USA ... insurance policy rates that are featured by leading companies ... plans that are offered are mixed between three of ... to 79. There are now term, universal and whole ...
Breaking Medicine News(10 mins):Health News:Orange County Facial Plastic Surgeon Featured in Premier Magazine Focused on Beauty 2Health News:Orange County Facial Plastic Surgeon Featured in Premier Magazine Focused on Beauty 3Health News:Tampa Bay Times Selects Florida Hospital Wesley Chapel, Florida Hospital at Connerton Long Term Acute Care and Florida Hospital Carrollwood As Top Workplaces in Tampa Bay 2Health News:Tampa Bay Times Selects Florida Hospital Wesley Chapel, Florida Hospital at Connerton Long Term Acute Care and Florida Hospital Carrollwood As Top Workplaces in Tampa Bay 3Health News:Tampa Bay Times Selects Florida Hospital Wesley Chapel, Florida Hospital at Connerton Long Term Acute Care and Florida Hospital Carrollwood As Top Workplaces in Tampa Bay 4Health News:The Last Well and Liberty U’s TEN Initiative raises $21,000 to Bring Fresh Water & The Gospel to 7,000 Liberians 2Health News:General Life Insurance Policy Rates Added to Quotation System at Insurance Website Online 2
... Agreement Provides for Provider Services, Inc. to fund $600,000 for Product, ... Millennium pursuant to the terms of the $20,000,000 5-year Purchase ... ... N.J., Jan. 16 Millennium Biotechnologies,Inc., wholly owned subsidiary of Millennium ...
... 16 STERIS Corporation,(NYSE: STE ) today ... third,quarter earnings release before the market opens on ... 10:00 a.m. Eastern time. The conference,call can be ... or via phone,by dialing 1-888-392-9976 in the ...
... OMI Medical Imaging, Inc. (OMI),announced today that it ... the U.S. Bankruptcy Court for the Southern District of,Florida ... Act reimbursement cuts took effect on,January 1, 2007, the ... its secured lenders., OMI operates 21 free standing ...
... could show who will respond best to interferon beta ... differences might explain why some multiple sclerosis (MS) patients ... study. , Starting with 206 southern European patients with ... the researchers compared the DNA of patients whose symptoms ...
... at LSU Health Sciences Center New Orleans has been ... the William J. Gies Award for Outstanding Innovation. The ... a black-tie celebration on March 29, 2008 in conjunction ... Session at the Hilton Anatole in Dallas, Texas. Named ...
... CINCINNATI Human evolution has created enhancements in key ... so-called guardian of the genome by creating additional ... to guard against DNA damage that could cause cancer ... of scientists led by Cincinnati Childrens Hospital Medical Center ...
Cached Medicine News:Health News:Millennium Enters Into $600,000 Product Development Agreement to Fund Product Development for the $20,000,000 Purchase Agreement with Provider Services, Inc. 2Health News:STERIS Corporation Announces Date of Fiscal 2008 Third Quarter Earnings Release and Conference Call 2Health News:STERIS Corporation Announces Date of Fiscal 2008 Third Quarter Earnings Release and Conference Call 3Health News:OMI Medical Imaging, Inc. and Affiliated Companies File Chapter 11 Reorganization 2Health News:DNA Analysis Could Help Customize Treatments for MS 2Health News:LSUHSC dental school to be awarded top national honor 2Health News:Evolution of human genome's 'guardian' gives people unique protections from DNA damage 2Health News:Evolution of human genome's 'guardian' gives people unique protections from DNA damage 3Health News:Evolution of human genome's 'guardian' gives people unique protections from DNA damage 4
(Date:4/16/2015)... April 16, 2015 Vanda Pharmaceuticals Inc. (Vanda) ... the development and commercialization of products for the treatment ... release results for the first quarter of 2015 on ... The Company will host a conference call ... during which Vanda management will discuss the first quarter ...
(Date:4/16/2015)... April 16, 2015  Hologic, Inc. (NASDAQ: ... screening study i published on-line this week ... of the American Cancer Society. The ... of Pittsburgh Medical Center, supports current consensus guidelines ii ... women 30-65 years of age be co-tested with ...
(Date:4/16/2015)... April 16, 2015 Mallinckrodt plc (NYSE: ... today announced that it has completed its acquisition ... approximately $2.3 billion. The Ikaria acquisition extends Mallinckrodt,s ... reach into neonatal critical care with INOMAX ® ... for a highly vulnerable patient population. It also ...
Breaking Medicine Technology:Vanda Pharmaceuticals to Announce First Quarter 2015 Financial Results on May 6, 2015 2Hologic Comments on Important Cervical Cancer Screening Study Published in the American Cancer Society Journal, Cancer Cytopathology 2Hologic Comments on Important Cervical Cancer Screening Study Published in the American Cancer Society Journal, Cancer Cytopathology 3Hologic Comments on Important Cervical Cancer Screening Study Published in the American Cancer Society Journal, Cancer Cytopathology 4Mallinckrodt Completes Acquisition Of Ikaria 2Mallinckrodt Completes Acquisition Of Ikaria 3Mallinckrodt Completes Acquisition Of Ikaria 4Mallinckrodt Completes Acquisition Of Ikaria 5
... 2007 - Pro-Pharmaceuticals,Inc. (Amex: PRW), a developer ... Eliezer Zomer, Ph.D., Executive Vice,President, Product Development ... Advanced Solid Tumors of,5-FU with an Admixture ... of Oncodevelopmental Biology and Medicine,(ISOBM) Conference to ...
... Investigative Dermatology, FREEPORT, N.Y., May 16, 2007 ... clinical data that indicates,that OCTN-1 skin cells ... L-ergothioneine (EGT) as a protector against oxidative,damage, ... more powerful and,efficient antioxidant than idebenone, scavenging ...
Cached Medicine Technology:Pro-Pharmaceuticals to Present Abstract at the International,Society of Oncodevelopmental Biology and Medicine Conference 2Pro-Pharmaceuticals to Present Abstract at the International,Society of Oncodevelopmental Biology and Medicine Conference 3Pro-Pharmaceuticals to Present Abstract at the International,Society of Oncodevelopmental Biology and Medicine Conference 4Pro-Pharmaceuticals to Present Abstract at the International,Society of Oncodevelopmental Biology and Medicine Conference 5AGI Dermatics Presents Comparative Data That Indicates OCTN-1 Skin,Cells Have the Ability to Recognize, Transport and Utilize,L-ergothioneine (EGT) As A Protector Against Oxidative Damage 2
Liquichek™ Ethanol/Ammonia Control is a liquid product used to monitor ethanol and ammonia test procedures in the clinical laboratory....
Lyphochek Assayed Chemistry Control requires no special diluent and has good reconstituted stability for enzymes and CO2. It is assayed for most major instruments and methodologies....
Lyphochek Benzo/TCA Control Set B is ideal for monitoring HPLC methods for identification and quantitation of benzodiazepines and antidepressant drugs....
Lyphochek Endocrine Control is a human based product designed to monitor plasma catecholamine testing procedures by HPLC. The analytes are spiked at critical concentrations to cover the dynamic range...
Medicine Products: