Navigation Links
Explaining Stevia's bitter side
Date:5/31/2012

The human tongue has just one receptor type for detecting sweetness but about25 different ones for bitter flavors. Scientists at Technische Universitaet Muenchen (TUM) and the German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE) have now identified the two receptors, hTAS2R4 and hTAS2R14, that detect the bitter after taste of Stevia.

Extracts from the subtropical plants are up to 300 times sweeter than conventional sugar. They also contain almost no calories and are less harmful to teeth. Yet Stevia, or sweet leaf, as it is more commonly known, also has its disadvantages: At high concentrations, it elicits licorice-like aromas and a bitter after taste.

The scientists investigated nine Steviol glycosides responsible for the intensive sweet taste of Stevia plant extracts. They initially tested the bitterness or sweetness that each glycoside evokes in vitro, using cells that act as taste receptor cells and react to the glycoside molecules like an artificial tongue. The researchers were thus able to identify the receptors that are activated by Stevia.

They also tested the taste intensity of different concentrations of Stevia components with trained volunteers. The results of those sensory tests combined with the initial cell experiments revealed that the structure of glycoside molecules plays a key role in determining sweetness or bitterness in Stevia. "If a molecule has more glucose molecules attached to it, it is sweeter and less bitter," explains Prof. Thomas Hofmann, Chair of Food Chemistry and Molecular Sensory Science at TUM. The Steviol glycoside rebaudioside D, for example, comprises five glucose molecules and is around five times sweeter and two-thirds less bitter than dulcoside A, which has just two glucose molecules.

"Steviol glycosides activate two bitter receptors on the human tongue, and this elicits a bitter after taste in the mouth," confirms Anne Brockhoff at the German Institute of Human Nutrition. These new findings could help minimize the bitter taste of Stevia products at an early stage in production processes. "They could open the way for selective cultivation measures or targeted purification during the development of Stevia products, enabling manufacturers to focus on the sweetest candidates," confirms TUM scientist Thomas Hofmann.


'/>"/>

Contact: Undine Ziller
ziller@zv.tum.de
49-816-171-5403
Technische Universitaet Muenchen
Source:Eurekalert

Related medicine news :

1. Brochures explaining new health care law to patients available free in English and Spanish
2. Bitter sensitive children eat more vegetables with help of dip
3. Bitter Taste Receptors Found in Lungs May Aid Asthma Patients
4. Bitrex Bitter Safety Additive Exhibiting at the Safe Kids Fair 2010; Making a Bitter Face to Learn about Poisoning Prevention
5. Bitter Melon Extract May Slow, Stop Breast Cancer
6. Bitter melon extract decreased breast cancer cell growth
7. Bitter melon extract attacks breast cancer cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2017)... ... 25, 2017 , ... Creative Pharmacist and ... the Pharmacist eCare Plan to Computer-Rx pharmacies through the STRAND platform. ... to develop the Pharmacist eCare Plan, a shared document detailing a patient’s current ...
(Date:7/25/2017)... ... July 25, 2017 , ... Dr. Gina Negrette, a skilled ... than a decade of experience in psychiatry, treating clients in diverse settings, including ... disorders, psychotic and manic conditions, as well as those who were fighting simply ...
(Date:7/24/2017)... , ... July 24, 2017 ... ... Director,      (407) 916-7235, kklaproth(at)robinsmorton(dot)com , Robins & Morton, Perkins ... to celebrate the structural topping out of the new Destination Medical Building ...
(Date:7/24/2017)... MD (PRWEB) , ... July 24, 2017 , ... ... Public Schools (MCPS) have partnered together for a unique opportunity that helps high school ... mission of “Removing Barriers, Creating Opportunities.” Horizon Goodwill will host over 20 ...
(Date:7/24/2017)... CLARA, CA (PRWEB) , ... July 24, 2017 , ... ... and financial organizations, today announced it has partnered with WALLIX to expand ... Special Publication 800-171 . , There are a number of ways to address the ...
Breaking Medicine News(10 mins):
(Date:7/11/2017)... founder of Echenberg Institute, is announcing a new safe and effective at-home ... and other painful pelvic pain conditions such as pelvic floor dysfunction, vulvodynia, ... ... ... start-up company, VuVatech LLC, fills a void in the women,s wellness market ...
(Date:7/10/2017)... COLUMBIA, S.C. , July 10, 2017 /PRNewswire/ ... product purchasing and patient support services organization serving ... announced today the launch of four significant, value-added ... into market insights, better manage reimbursement and improve ... Ig and factor therapies. ...
(Date:7/5/2017)... 5, 2017 Wolfmet 3D  printed tungsten collimator manufactured by ... and manufacturing combine to progress molecular radiotherapy imaging. ... are unable to accurately quantify the radiation absorbed by those ... the success of this radiotherapy treatment has been available — ... ...
Breaking Medicine Technology: