Navigation Links
Experts call for better research into link between women's hormones and mood disorders
Date:12/12/2007

Countless movies and TV shows make light of womens so-called moodiness, often jokingly attributing it to their menstrual cycle or, conversely, to menopause. In fact, mood disorders are a serious and pervasive health problem, and large-scale population studies have found women are 1.5 to 3 times more likely to suffer from major depressive disorder than are men.

In a newly published study, womens health experts from the University of Alberta argue there is an urgent need for carefully designed, gender-specific research to better understand the relationship of female sex hormones to mood states and disorders.

The reasons for the gender disparity in rates of depression are not completely understood, says Kathy Hegadoren, the Canada Research Chair in Stress Disorders in Women at the University of Alberta.

But there is growing evidence that estrogens have powerful effects beyond their role in reproductionthat they play a critical role in mood disorders in womenand this opens new avenues for research into the underlying biological mechanisms and treatment of depression.

Estrogen can be used to treat various mood disturbances in womensuch as perimenopausal, postmenopausal and postpartum depressionbut the results of these treatments can be difficult to interpret because researchers are only beginning to recognize the complex interactions among estrogens, serotonin and mood.

Right now, clinical use of sex-hormone therapies for the treatment of mood disorders is severely hampered by the inability to predict which women would respond well to such therapies, explains study co-author and U of A nursing professor Gerri Lasiuk.

Most animal studies looking at the causes of depression have been conducted with male animals and use chronic-stress models, which are assumed to be similar to depression.

Hegadoren and Lasiuks study recognizes that multiple factors may be at play in the development of mood disturbances, with individual, psychosocial and environmental factors interacting in complicated ways to create differential vulnerability in women and men. But they also point out that the link to sex hormones is hard to deny.

Previous research has found that, before puberty, the rates of mood and anxiety disorders are similar in boys and girls. Its only after females begin menstrual function that a gender differential in mood disorders manifests itself. This, coupled with the observation that women appear to be especially vulnerable to mood disturbances during times of hormonal flux, certainly lends support to the claim that a relationship exists between sex hormones and mood, says Hegadoren.


'/>"/>

Contact: Isabela C. Varela
isabela.varela@ualberta.ca
780-492-6041
University of Alberta
Source:Eurekalert

Related medicine news :

1. Research Links TV/Video Game Playing With Child Obesity; Health Experts Back a New Approach
2. Childrens Experts Warn: Dont Ignore Kids On National Depression Screening Day, October 11
3. MultiVu Video Feed: PUBLIC HEALTH EXPERTS CONVENE TO DISCUSS THE TREATMENT AND PREVENTION OF RABIES
4. Health IT Event Draws Experts to the Pacific Northwest
5. Experts Sort Out Good Fats From Bad
6. Experts Offer Tips on Lung Cancer Prevention
7. March of Dimes, Experts for Moms and Babies, Launches Podcast
8. World fertility experts to meet in Montreal - IVF and IVM patients to provide first-person accounts at 14th World Congress
9. Bay IVF Experts Launch One of First East-West Fertility Programs of Its Kind
10. Experts propose cholesterol tests at 15 months of age
11. Experts Publish New Lung Disease Guidelines
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/23/2017)... (PRWEB) , ... February 23, 2017 , ... ... outlet with a clinician-based audience, will be participating in Rare Disease Day events, ... Washington, D.C. In addition, Rare Disease Report, a website, weekly e-newsletter and quarterly ...
(Date:2/23/2017)... ... February 23, 2017 , ... Rosica Communications, a national ... marketing, social media management, corporate communications, SEO and cause marketing, is opening an ... nearby New Hampshire, Massachusetts and Canada, Rosica will focus on expanding its footprint. ...
(Date:2/23/2017)... ... February 23, 2017 , ... Pink Pig Publishing ... generations converge and explore the world from different perspectives. By providing a place ... to gain understanding, increase empathy, and find greater happiness. , "Our approach ...
(Date:2/23/2017)... ... 2017 , ... The Center for Autism and Related Disorders ... Research and Treatment (RI-CART) and Cinemaworld to present Sensory Friendly Films. The events ... films in an environment that accommodates their unique needs. , Launched in January, ...
(Date:2/23/2017)... ... 2017 , ... Curemark, LLC announced today that the Blüm Study, a Phase ... 3-8 with Autism, is now enrolling at three new sites. These new sites are ... , “There are currently no approved drugs that address the core symptoms of ...
Breaking Medicine News(10 mins):
(Date:2/23/2017)... , Feb 23, 2017 Research and Markets ... & Trends - Industry Forecast to 2025" report to their ... The ... around 6.9% over the next decade to reach approximately $47.6 billion ... estimates and forecasts for all the given segments on global as ...
(Date:2/23/2017)... February 23, 2017 The fast-growing cannabis ... the United States . According to the 2017 Legal ... is expected to create 283,422 jobs by 2020, with an ... the next four years. The accelerating pace of cannabis legalization ... of legal cannabis market, which will further create more business ...
(Date:2/23/2017)... , February 23, 2017 ... on the global market for intraoperative imaging, excerpts ... valued at US$ 513.9 million. According to the ... surging on the grounds of increasing adoption of ... field of diagnostic imaging for neurosurgeries. The world,s ...
Breaking Medicine Technology: