Navigation Links
Experts call for better research into link between women's hormones and mood disorders
Date:12/12/2007

Countless movies and TV shows make light of womens so-called moodiness, often jokingly attributing it to their menstrual cycle or, conversely, to menopause. In fact, mood disorders are a serious and pervasive health problem, and large-scale population studies have found women are 1.5 to 3 times more likely to suffer from major depressive disorder than are men.

In a newly published study, womens health experts from the University of Alberta argue there is an urgent need for carefully designed, gender-specific research to better understand the relationship of female sex hormones to mood states and disorders.

The reasons for the gender disparity in rates of depression are not completely understood, says Kathy Hegadoren, the Canada Research Chair in Stress Disorders in Women at the University of Alberta.

But there is growing evidence that estrogens have powerful effects beyond their role in reproductionthat they play a critical role in mood disorders in womenand this opens new avenues for research into the underlying biological mechanisms and treatment of depression.

Estrogen can be used to treat various mood disturbances in womensuch as perimenopausal, postmenopausal and postpartum depressionbut the results of these treatments can be difficult to interpret because researchers are only beginning to recognize the complex interactions among estrogens, serotonin and mood.

Right now, clinical use of sex-hormone therapies for the treatment of mood disorders is severely hampered by the inability to predict which women would respond well to such therapies, explains study co-author and U of A nursing professor Gerri Lasiuk.

Most animal studies looking at the causes of depression have been conducted with male animals and use chronic-stress models, which are assumed to be similar to depression.

Hegadoren and Lasiuks study recognizes that multiple factors may be at play in the development of mood disturbances, with individual, psychosocial and environmental factors interacting in complicated ways to create differential vulnerability in women and men. But they also point out that the link to sex hormones is hard to deny.

Previous research has found that, before puberty, the rates of mood and anxiety disorders are similar in boys and girls. Its only after females begin menstrual function that a gender differential in mood disorders manifests itself. This, coupled with the observation that women appear to be especially vulnerable to mood disturbances during times of hormonal flux, certainly lends support to the claim that a relationship exists between sex hormones and mood, says Hegadoren.


'/>"/>

Contact: Isabela C. Varela
isabela.varela@ualberta.ca
780-492-6041
University of Alberta
Source:Eurekalert

Related medicine news :

1. Research Links TV/Video Game Playing With Child Obesity; Health Experts Back a New Approach
2. Childrens Experts Warn: Dont Ignore Kids On National Depression Screening Day, October 11
3. MultiVu Video Feed: PUBLIC HEALTH EXPERTS CONVENE TO DISCUSS THE TREATMENT AND PREVENTION OF RABIES
4. Health IT Event Draws Experts to the Pacific Northwest
5. Experts Sort Out Good Fats From Bad
6. Experts Offer Tips on Lung Cancer Prevention
7. March of Dimes, Experts for Moms and Babies, Launches Podcast
8. World fertility experts to meet in Montreal - IVF and IVM patients to provide first-person accounts at 14th World Congress
9. Bay IVF Experts Launch One of First East-West Fertility Programs of Its Kind
10. Experts propose cholesterol tests at 15 months of age
11. Experts Publish New Lung Disease Guidelines
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... ... The American Board of Family Medicine's (ABFM) Board of Directors has selected ... Dr. James C. Puffer upon his retirement. Dr. Newton will serve in the position ... the end of 2018. Upon assuming the role of President and CEO on January ...
(Date:10/13/2017)... Shelton, CT (PRWEB) , ... October 13, 2017 , ... ... and long-term care services, staged a mock evacuation of the facility as part of ... Department, Shelton Fire Department, Echo Hose EMS and Shelton City Emergency Manager, as well ...
(Date:10/13/2017)... ... 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House of ... popular and least understood books in the Holy Scriptures, Revelation. The Book of Revelation ... scholars for centuries. Many have tossed it off as mere rubbish, but Yisrayl Hawkins ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... healthcare compliance program management, will showcase a range of technology and learning solutions ... Living (NCAL) Convention and Expo to be held October 14–18, 2017 at the ...
(Date:10/12/2017)... Bethesda, MD (PRWEB) , ... October 12, 2017 , ... ... Award of Excellence to Carol Friedman, PhD, FACMI, during the Opening Session of AMIA’s ... 4 – 8. , In honor of Morris F. Collen, a pioneer in the ...
Breaking Medicine News(10 mins):
(Date:10/4/2017)... 2017 OBP Medical , a ... devices, today announced regulatory approval from ... Agência Nacional de Vigilância Sanitária (ANVISA)) to market ... retractor with integrated LED light source and smoke ... exposure of a tissue pocket or cavity during ...
(Date:10/2/2017)... The Rebound mobile app is poised to become ... tide of prescription drug addiction. The app empowers users to ... stepping down their dosage in a safe, controlled manner while ... the first 100,000 people to sign up will enjoy 3 ... ...
(Date:9/25/2017)... , Sept. 25, 2017   Montrium , ... File solutions, today—from the IQPC Trial Master Files ... , NL)—announced that EastHORN Clinical Services has selected ... programs and TMF management. EastHORN, a leading European ... platform to increase transparency to enable greater collaboration ...
Breaking Medicine Technology: