Navigation Links
Experts Revise Guidelines on Daily Aspirin for Heart
Date:3/16/2009

Lower dose appears safe and effective against heart attack in men, stroke in women

MONDAY, March 16 (HealthDay News) -- Amid the continuing debate over who should pop an aspirin each day to fight heart disease, and at what dose, U.S. experts have revised guidelines stating that lower doses appear to be at least as effective as higher doses and safer at preventing heart attack and stroke.

The issue of dosage has long been discussed because aspirin carries with it an increased risk for gastrointestinal bleeding, especially when taken in combination with the clot-dissolving drug clopidogrel (Plavix).

The new U.S. Preventive Services Task Force guidelines are tailored to match age and gender. Among the recommendations: Men aged 45 to 79 should take aspirin if the chances of preventing a heart attack outweigh the chances of gastrointestinal bleeding. Women aged 55 to 79 should take the drug if the chances of reducing ischemic stroke outweigh the risks of GI bleeding.

"Subsequent to the 2002 recommendations, there was more information that came out of the Women's Health Initiative, specifically, that enabled us to look at this recommendation by gender," said Dr. Michael LeFevre, a task force member and professor of family and community medicine at the University of Missouri, Columbia. "We have a recommendation for men and a recommendation for women. We did not have that before."

Aspirin seems to be more effective in men for preventing heart attack but, in women, better at preventing stroke, LeFevre added.

Dr. Carl J. Lavie, medical director of cardiac rehabilitation at the Ochsner Heart and Vascular Institute in New Orleans, added: "The benefits of aspirin use always have to be balanced against the risks. If a patient has low risk of events in the near future, aspirin should not be prescribed. If the risk is very high, clearly aspirin is needed."

The recommendations, published in the March 17 issue of the Annals of Internal Medicine, state:

  • Men aged 45 to 79 with heart risk factors should take aspirin if the preventive benefits outweigh the risk of bleeding.
  • At-risk women aged 55 to 79 should take aspirin if the odds of reducing a first ischemic stroke outweigh the chance of bleeding.
  • Men under the age of 45 and women under 55 who have never had a heart attack or stroke should not take aspirin for prevention.
  • At this time, it isn't clear whether patients aged 80 and older should take aspirin.

The task force emphasized that the recommendations only apply to people who have never had a heart attack or stroke.

The last task force recommendations came out in 2002. At the time, the panel acknowledged that the evidence for the use of aspirin in preventing heart problems was still evolving.

A second paper in the same issue of the journal reaffirms the task force guidelines, finding that lower doses of daily aspirin (75 milligrams to 81 milligrams) are equally, if not more effective, than higher doses (100 mg or more) in preventing heart attack and stroke in at-risk individuals.

The paper also found that high doses may actually do more harm, especially in people taking Plavix.

According to background information in the study, aspirin is the most used drug worldwide to prevent heart attack and stroke. More than one-third of U.S. adults are believed to take aspirin each day.

"All these trials put together really favor taking lower doses of aspirin," said Dr. Suzanne Steinbaum, director of women and heart disease at Lenox Hill Hospital in New York City.

More information

Calculate your risk of coronary heart disease at the Medical College of Wisconsin.



SOURCES: Michael LeFevre, M.D., member, U.S. Preventive Services Task Force, and professor, family and community medicine, University of Missouri, Columbia; Suzanne Steinbaum, D.O., director, women and heart disease, Lenox Hill Hospital, New York City; Carl J. Lavie, M.D., medical director, cardiac rehabilitation, Ochsner Heart and Vascular Institute, New Orleans; March 17, 2009, Annals of Internal Medicine


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Experts Weigh in on Controversial Issue of Determining Value of Cancer Care at NCCN Conference
2. Wound Be Gone: Quickly Gaining Strong Support from Clinician Experts in the Field of Wound Healing
3. HIV Experts Propose New Approach to Eradicate HIV in Latest Issue of Science
4. Experts examine causes, treatment and prevention of glaucoma
5. SilverCensus.com Names Consumer Affairs Advocate, Healthcare Experts to Provide Free Educational Support for Seniors
6. Policy experts urge scrutiny of senior tax breaks
7. Interview with GI Experts: Discussions in Clostridium difficile
8. Burn rehabilitation experts at UT Southwestern outline best treatments for post-burn itching
9. Rush University Medical Center experts present latest research findings at AAOS meeting
10. Health experts urge supermarket pharmacies to get smart about free antibiotics
11. Experts Call for FDA Regulation of Tobacco Products
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House of ... popular and least understood books in the Holy Scriptures, Revelation. The Book of Revelation ... scholars for centuries. Many have tossed it off as mere rubbish, but Yisrayl Hawkins ...
(Date:10/13/2017)... VA (PRWEB) , ... October 13, 2017 , ... ... of DevOps and Agile Software Development, has been awarded a contract by the ... Blanket Purchase Agreement (BPA) aims to accelerate the enterprise use of Agile methodologies ...
(Date:10/13/2017)... ... October 13, 2017 , ... “America On The Brink”: ... “America On The Brink” is the creation of published author, William Nowers. ... As a WWII veteran, he spent thirty years in the Navy. Following ...
(Date:10/12/2017)... ... October 12, 2017 , ... CitiDent and San Francisco ... using cutting-edge Oventus O2Vent technology. As many as 18 million Americans are estimated ... in breathing. Oral appliances can offer significant relief to about 75 percent of ...
(Date:10/12/2017)... WAUSAU, Wis. (PRWEB) , ... October 12, 2017 ... ... formulated standard products to meet the demand of today’s consumer and regulatory authorities ... team of probiotic experts and tested to meet the highest standard. , ...
Breaking Medicine News(10 mins):
(Date:10/4/2017)... SEOUL, South Korea , Oct. 4, 2017 /PRNewswire/ ... launched its next-generation CPR training aide "cprCUBE" on Kickstarter. ... of chest compression during cardiac arrests with better efficiency ... patient-mannequins. It also offers real-time feedback on efficacy of ... The crowdfunding campaign has a goal to raise ...
(Date:10/2/2017)... 2, 2017 Diplomat Pharmacy, Inc. (NYSE: ... and Consulting, LLC , and named its founder as ... in Tennessee , will operate under ... EnvoyHealth,s service offerings for health care partners to include ... "In an interoperable world, technology delivers ...
(Date:10/2/2017)... 2, 2017 Halo Labs announces the European launch of ... the HORIZON at MIBio 2017 in Cambridge, U.K ... particulate matter in biopharmaceutical samples with unprecedented speed and sensitivity while ... technique Backgrounded Membrane Imaging. ... HORIZON subvisible particle analysis system ...
Breaking Medicine Technology: