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Expert analysis of HER2 tests reveals issues with reliability, Mayo Clinic researchers say
Date:12/11/2010

had normal HER2 results but who were still treated with Herceptin responded well to the treatment, she adds. "This may dispel the notion that Herceptin may be of benefit in women with truly normal HER2 tumors."

And the disagreement seen throughout this study can also help explain some of the variability in results seen between central and local laboratories, Dr. Perez says.

"It is necessary for oncologists to continue to refine these tests and their analysis," she says. "That may mean some tests may be needed for multiple tumor blocks, or that pathologists may need to discuss borderline results for some patients."


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Contact: Nicole Engler
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

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