Navigation Links
Experimental drug shows promise in advanced kidney cancer
Date:9/26/2007

Barcelona, Spain: A new drug has shown promise in patients with advanced kidney cancer whose options run out after their tumour fails to respond to the cutting edge therapy.

The study, presented today (Wednesday) at the European Cancer Conference (ECCO 14) in Barcelona, showed that the experimental drug, axitinib, shrank tumours and delayed progression of the disease in a group of patients who are among the toughest to treat.

In the study, scientists gave axitinib to 62 patients whose kidney cancer had spread and who had not benefited from a standard treatment, sorafenib, a targeted therapy designed to disrupt cell division signals in cancer cells and block the tumours ability to form new blood vessels that help it grow. Fourteen of the patients also had been given to no avail another similarly targeted drug, sunitinib, after the sorafenib had failed to work. Axitinib works similarly to the other two but is believed to be more potent.

More than half the patients 51 percent experienced tumour shrinkage and in 23 percent of them the shrinkage is considered significant, said lead investigator Dr Brian I. Rini, an associate professor of medicine at the Cleveland Clinic Taussig Cancer Institute in Cleveland, Ohio, USA, and a paid member of the Pfizer scientific advisory board. Preliminary analysis shows the progression-free survival was on average more than 7.7 months. We think these results are impressive because these patients were heavily pre-treated and with drugs thought to be similar to axitinib.

The disease progressed in only 24 percent of patients, which we think is low in this kind of setting, Rini added. The study found the tumour remained stable in 37 percent of the patients.

Historically, metastatic kidney cancer has been very tough to treat, with a median survival of 12 months. Through the results of this trial, it appears that axitinib is a very active drug in renal cell cancer that can benefit a large
'/>"/>

Contact: Emma Ross
rosswrite@mac.com
34-932-308-832
ECCO-the European CanCer Conference
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Experimental treatment for Ebola Virus Shows promising results in mice
2. FDA approves Phase 0 trial which tests experimental drugs on humans
3. Experimental drug to fight flu
4. Experimental SARS Vaccine
5. Experimental vaccine for shingles is effective
6. Experimental Blood Test May Spot Heart Attack Risk, Study Says
7. Five AIDS Patients To Receive Experimental Anti-retroviral Drugs
8. TMC 114 and 125 experimental drugs to be tested on four HIV patients
9. Protection against HIV and Herpes is possible with the Experimental Microbicide
10. Experimental Therapy Effective Against Malignant Melanoma in Horses
11. Experimental Alzheimer’s Drug curbs the disease in mic
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/16/2014)... Registration is now open for the ... 10K, 5K, and 1-mile walk/run to be held on ... Local 338 RWDSU/UFCW, the Town of Babylon, and Island ... of Babylon Town Hall in Lindenhurst, NY. Registration is ... is organized by Hope For The Warriors®, a national ...
(Date:9/16/2014)... Alabama (PRWEB) September 16, 2014 *To find ... AL, visit Achieve Clinical Research on the web ( http://www.achieveclinical.com/trial/pneumonia-vaccine/ ... those who qualify:, There is no ... , Compensation may be provided for time ... pneumonia and influenza are the eighth leading cause of death ...
(Date:9/16/2014)... *Anyone who is interested in learning ... FL can visit Avail Clinical Research on the web ... 785-2404. , Why Are Volunteers Needed? , The common ... infecting mankind. While infections may not be as deadly ... more annual visits to the doctor than any other ...
(Date:9/16/2014)... justthoughtyoushouldknow.org , popular current events, ... new site today. The new site is better ... information easier to find, ingest, and share. , ... easy-to-read pages the information that we believe any ... retired college professor and founder of the site. ...
(Date:9/16/2014)... September 16, 2014 BQuick Nutrition is ... of its most popular products - BQuick BURN Clarinol ... educate the general public about the many benefits of ... building lean muscle mass. As well as having a ... benefits, supplement facts, and nutritional information - making it ...
Breaking Medicine News(10 mins):Health News:The Hope For The Warriors Long Island Run For The Warriors to Honor Wounded and Families of the Fallen 2Health News:The Team at Achieve Clinical Research is Enrolling Qualified Individuals to Participate in a Pneumonia Vaccine Clinical Trial in Birmingham, Alabama 2Health News:The Team at Achieve Clinical Research is Enrolling Qualified Individuals to Participate in a Pneumonia Vaccine Clinical Trial in Birmingham, Alabama 3Health News:Avail Clinical Research Is Looking for Healthy Adults Who Are Interested in Participating in a Common Cold Clinical Trial near Orlando, Florida 2Health News:Avail Clinical Research Is Looking for Healthy Adults Who Are Interested in Participating in a Common Cold Clinical Trial near Orlando, Florida 3Health News:JustThoughtYouShouldKnow.org Debuts New Website 2Health News:BQuick Nutrition Announces Newly Branded BURN Clarinol CLA Powder 2Health News:BQuick Nutrition Announces Newly Branded BURN Clarinol CLA Powder 3
... be promising news in the quest to find a ... (ALS), or Lou Gehrigs disease, scientists at the University ... shown that targeting neuronal support cells called astrocytes sharply ... in the laboratory of Don Cleveland, Ph.D., UCSD Professor ...
... to prove anecdotes that canines can smell dangerous drops in ... Irish researchers hope to prove that a dog,s keen sense ... blood sugar levels of diabetics. , Canines have already shown ... helping the physically disabled with daily tasks. , But researchers ...
... found that the gene ENPP1 is linked to preterm ... , Errol Norwitz, M.D., associate professor in the Department ... present preliminary results from this research at the Society ... in Dallas, Texas. , One out of eight babies ...
... Survey says latent infections among immigrants, minorities, poor thwart ... -- It appears that the United States will fall ... according to an analysis of National Health and Nutritional ... of latent TB infection (LTBI) in the U.S. population ...
... February 2, 2008 One-year data from a second ... given every 12 weeks provided sustained, clinically meaningful improvement ... through one year. According to findings presented at ... 87 percent of patients responding to ustekinumab 45 mg ...
... 1 Kristin Davis, star,of US hit TV show ... leading AIDS,activists at a Johannesburg press conference tomorrow, Saturday, ... and AIDS epidemic in,South Africa., (Photo: http://www.newscom.com/cgi-bin/prnh/20080201/LAF106-a ... http://www.newscom.com/cgi-bin/prnh/20080201/LAF106-b ) Kristin, ...
Cached Medicine News:Health News:Targeting astrocytes slows disease progression in ALS 2Health News:Dogs Could Be a Diabetic's Best Friend 2Health News:Dogs Could Be a Diabetic's Best Friend 3Health News:Dogs Could Be a Diabetic's Best Friend 4Health News:Gene linked to preterm birth among Hispanic women 2Health News:U.S. Unlikely to Meet Target for TB Elimination 2Health News:Ustekinumab Phase 3 data show long-term improvement of chronic plaque psoriasis 2Health News:Ustekinumab Phase 3 data show long-term improvement of chronic plaque psoriasis 3Health News:Ustekinumab Phase 3 data show long-term improvement of chronic plaque psoriasis 4Health News:'Sex & the City' Gets Serious About HIV and AIDS in South Africa - Kristin Davis Helps Oxfam Break the Stigma and Close the Treatment Gaps Fuelling AIDS 2Health News:'Sex & the City' Gets Serious About HIV and AIDS in South Africa - Kristin Davis Helps Oxfam Break the Stigma and Close the Treatment Gaps Fuelling AIDS 3
(Date:9/15/2014)... Quebec , Sept. 15, 2014  Valeant Pharmaceuticals ... announced that its wholly owned subsidiary, Valeant Pharmaceuticals International, ... principal amount of its 6.75% Senior Notes due 2017, ... October 15, 2014 and has mailed an irrevocable notice ... 15, 2014, a copy of the irrevocable notice of ...
(Date:9/15/2014)... DALLAS , Sept. 15, 2014 /PRNewswire-iReach/ -- MedicOne ... ambulance transport services, has been selected by Inc. ... companies in America. Photo - ... Inc. 500|5000 list identifies successful, privately-held companies with ... MedicOne Medical Response, one of only two ambulance ...
(Date:9/15/2014)... SINGAPORE , Sept. 15, 2014  Catalist-listed QT ... "the Group"), a developer and manufacturer of minimally invasive ... pleased to announce that the Group has enrolled the ... Germany . Multiple patients have already been ... , at Auckland City Hospital, in Auckland, ...
Breaking Medicine Technology:Valeant Announces Redemption of All of the Outstanding $500.0 Million Aggregate Principal Amount of its 6.75% Senior Notes due 2017 2MedicOne Medical Response Named to 2014 Inc. 5000 Fastest Growing Companies List 2MedicOne Medical Response Named to 2014 Inc. 5000 Fastest Growing Companies List 3First European Patients Enrolled in QT Vascular's ENDURE Trial 2First European Patients Enrolled in QT Vascular's ENDURE Trial 3First European Patients Enrolled in QT Vascular's ENDURE Trial 4First European Patients Enrolled in QT Vascular's ENDURE Trial 5
... (Nasdaq: ISIS ), the leader in antisense therapeutics, today ... Adams, 2009 Cardiovascular Conference on Tuesday, November 10, 2009, at ... , A live audio webcast of the presentation will be ... Web site, www.isispharm.com . A replay ...
... WASHINGTON, Nov. 2 The owner and operator of ... guilty to defrauding the Medicare program, announced Assistant Attorney ... Attorney Tim Johnson of the Southern District of Texas ... of Health & Human Services (HHS). , Noel Wayne ...
Cached Medicine Technology:Medical Equipment Company Owner Pleads Guilty to Fraud Scheme Involving Nutritional Supplies and "Arthritis Kits" 2Medical Equipment Company Owner Pleads Guilty to Fraud Scheme Involving Nutritional Supplies and "Arthritis Kits" 3
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: