Navigation Links
Experimental agents may prevent radiation-induced leukemia
Date:4/19/2009

DENVER Treatment with biphosphonates could prevent radiation-induced leukemia, according to data presented at the American Association for Cancer Research 100th Annual Meeting 2009.

Alexandra Miller, Ph.D., a senior scientist at the Armed Forces Radiobiology Research Institute, said her research is designed to help military and space agency personnel, who are more likely to be exposed to risky levels of radiation than the general population. However, she said the research could have applications for civilian populations as well.

"It is possible, although not yet proven, that the compound we studied could have a general effect on leukemia associated with causes other than radiation, such as age, which is much more common," said Miller.

The compounds Miller studied are biphosphonates known to scientists as ethane-1-hydroxy-1, 1-biphosphonate (EHBP) and carballylic amido bis phosphonic acid (CAPBP). Biphosphonates have emerged as an attractive chemopreventive agent due to earlier research that suggests they prevent bone metastasis and because they have an ability to remove uranium from the body.

For the current study, Miller and her colleagues irradiated laboratory mice at 3.5 Gy; all of the mice who were not treated with either EHBP or CAPBP developed leukemia.

By contrast, if they were treated with six doses of EHBP only 75 percent of mice developed leukemia. Similarly, only 65 percent of mice treated with CAPBP developed leukemia.


'/>"/>

Contact: Jeremy Moore
Jeremy.moore@aacr.org
267-646-0557
American Association for Cancer Research
Source:Eurekalert

Page: 1

Related medicine news :

1. Experimental insulin-like growth factor receptor inhibitor reduced pancreatic cancer growth
2. Hard to Treat Diseases (HTDS) Releases experimental results in the treatment of (MS) Multiple Sclerosis
3. Experimental Drug May Dampen Severe Asthma
4. Experimental Drug May Prevent Plaque Buildup
5. Experimental Biology 2009 meets April 18-22
6. Experimental Weight-Loss Pill Passes Early Test
7. Experimental Drug Fights Bone Marrow Cancers
8. Experimental Vaginal Gel Doesnt Ward Off HIV
9. Experimental TB drug explodes bacteria from the inside out
10. Cephalon and ImmuPharma Sign a $15 million Option Agreement for Late- Stage Experimental Lupus Medication
11. Phase II Trial of Experimental Anti-Coagulant Reports Safety and Outcomes Data
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/24/2017)... (PRWEB) , ... August 24, 2017 , ... ... supplements that help people improve all aspects of their health and wellness, has ... , The step represents a component of Natural Subsistence’s aggressive marketing strategy in ...
(Date:8/24/2017)... ... August 24, 2017 , ... AudioEducator is the country’s top ... coming months, AudioEducator has lined up several training sessions on ICD-10 coding ... experts, these healthcare training conferences are designed to update providers with all the ...
(Date:8/23/2017)... ... August 23, 2017 , ... ... President Business Development and Sector Growth. Mr. Smith joins other recent high-profile hires ... , Mr. Smith’s healthcare career began in 1993, helping physician practices and hospitals ...
(Date:8/23/2017)... ... ... The Stevie® Awards have announced the winners of the Best of the IBA Awards in ... , Nominees in the 2017 IBAs were not able to apply for the Best of ... number of awards won in the IBAs with a Gold Stevie win counting for three ...
(Date:8/23/2017)... , ... August 23, 2017 , ... ... MD , has returned home to Indiana, and is now seeing patients at ... board-eligible ophthalmologist that specializes in the diagnosis and treatment of eye disease, medical ...
Breaking Medicine News(10 mins):
(Date:8/7/2017)... (NYSE: DPLO), the nation,s largest independent specialty pharmacy, announced financial ... unless otherwise noted, are to the quarter ended June 30, ... 2017 Highlights include: Revenue of $1,126 ... Total prescriptions dispensed of 220,000, compared to 241,000 ... Gross profit per prescription dispensed of $371, ...
(Date:8/4/2017)... , Aug. 4, 2017 The search ... shortly after a physician/patient consult has long been the ... was a notable focus of the largest meeting of ... according to healthcare market research firm Kalorama Information.  The ... testing (POCT) offerings or related supplies and software were ...
(Date:8/3/2017)... Aug. 3, 2017  Opioid addiction and other drugs ... healthcare costs and threatening outcomes, were problems taken on ... IVD industry that support them, met this week. This ... said that drugs of abuse, procalcitonin and acute kidney ... the organization,s 69th meeting in San Diego, ...
Breaking Medicine Technology: