Navigation Links
Experimental agent blocks prostate cancer in animal study
Date:5/22/2008

n is also professor of pharmacy and of internal medicine.

A veterinary pathologist on the study, first author Aaron Sargeant, graduate research associate in veterinary biosciences, was intrigued that adenomas occurred in the treated animals. Adenomas are not commonly found to be part of prostate-cancer development in this system, he says. This drug appears to shift tumor progression from its usual aggressive course to a more benign direction.

For this study, Chen, Sargeant, Clinton and their colleagues used a strain of transgenic mice that develops PIN at about six weeks of age, then progresses to advanced prostate cancer by 24 to 32 weeks.

The researchers added the drug to the diet of 23 of the cancer-prone mice beginning at six weeks of age, when the animals develop the precancerous condition, and continued the treatment for 18 weeks.

They then examined the animals. Of the treated mice, one showed signs of early stage cancer, but 12 still had only the precancerous condition and 10 had adenomas.

In contrast, 17 of 23 control animals developed advanced prostate cancer, two had early stage cancer, three had the precancerous condition and one an adenoma.

Experiments using a nontransgenic strain of the same mouse they do not develop prostate cancer showed that the degeneration of the testicles that accompanied the drug treatment was reversible when the drug treatment stops.

Chen noted that 186,320 cases of prostate cancer are expected this year, with 28,660 deaths from the disease. Our findings are very exciting, considering that an agent capable of reducing prostate-cancer risk by only 10 percent could prevent 18,600 cases of the disease in the United States each year, Chen says.


'/>"/>

Contact: Darrell E. Ward
darrell.ward@osumc.edu
614-293-3737
Ohio State University Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Experimental Drug Eases Symptoms of Mild Alzheimers
2. Experimental Blood Substitutes Unsafe, Study Finds
3. Honda to Showcase Experimental Walking Assist Device
4. Experimental Alzheimers Drug Shows Promise
5. Experimental drug shows promise in treating certain lymphomas
6. Experimental Cancer Vaccines Show Promise
7. Gourmetceuticals Presents Findings on Science You Can Eat at Experimental Biology 2008
8. Cavities in Children Reduced Over 60 Percent by New Experimental Chewable Mints
9. Gourmetceuticals to Present Data from Four Studies at Experimental Biology 2008
10. 52 minority scientists receive travel fellowships to Experimental Biology 2008
11. Experimental Biology 2008 Todays Research: Tomorrows Health, April 5-9
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... Thousands of researchers from more than ... 13-17 to reveal the latest study results, theories ... in dementia science. The Alzheimer’s Association International Conference ... kind. , As part of the Alzheimer’s Association’s ... generating new knowledge about dementia and fostering a ...
(Date:7/10/2014)... his latest blog post at http://www.perwickstrom.com , entrepreneur, ... has listed 5 ways to follow-up without being annoying. ... information or sometimes even just return an inquiry, the ... skill that most people don’t have,” commented Per Wickstrom. ... moving without coming across as annoying – let alone ...
(Date:7/10/2014)... A new study from Colorado School of Public Health ... remains a major problem in the Navajo Nation and ... Native Americans is abysmal with more than three times ... Terrence Batliner, DDS, MBA, associate director of the Center ... Public Health. "The number one problem is access to ...
(Date:7/10/2014)... Teens who are sensitive to light or noise after ... such as anxiety and depression, a new study says. ... issues teens experience after concussion may help in planning ... when to return to play and what accommodations are ... Koehl and Dong Han, of the University of Kentucky ...
(Date:7/10/2014)... today,s announcement that the "Mississippi Baby," believed to have ... to have detectable levels of the virus, the Elizabeth ... setback but remains hopeful that the scientific breakthrough that ... more than two years will continue to help researchers ... cure. , "Although we had high hopes that ...
Breaking Medicine News(10 mins):Health News:Per Wickstrom’s Latest Blog Post Lists 5 Ways to Follow-up Without Being Annoying 2Health News:Study finds widespread oral health problems among Navajo 2Health News:Some Teens May Face Emotional Problems After Concussion 2Health News:Despite setback, 'Mississippi Baby' represents significant breakthrough in effort to end AIDS 2
... spent nearly 300 hours observing patients in an accident ... possible flashpoints , according to the latest Journal of ... research at the University of Western Sydney, Australia, points ... much wider applications than just hospitals. ,STAMP ...
... love Jenny McCarthy has revealed her plans about getting a lovely ... will be spending as much time as possible on the beach. ... and do nothing. Stare at the ocean and go 'ohhmmm, People ... a lot of time with her beau on the beach, although ...
... during her growing years that doctors thought she had brain tumour ... was eight till she was 13, when her parents separated. ... the stress of her parents troubled married life. ,The ... it was all in her head, and though the memories werent ...
... Programme (WFP) has warned that continuing security problems are hampering ... west of the country where food stocks are running short ... critical food supplies curtailed or interrupted. ,"WFP has ... Afghanistan for four weeks due to insecurity. Unless we can ...
... work that can cause your marriage to collapse, but it ... social survey - involving 14,000 people over five years - ... nearly twice as likely to end up in divorce, than ... it is having too much time that is causing stress," ...
... expert has organized a three-day workshop on the ancient Indian ... director of Yoga Darshan, India, in his lecture on Yoga, ... said, yoga could help the people of Lahore keep healthy, ... can help Lahoris keep healthy, said Dr Mishra, who holds ...
Cached Medicine News:Health News:Potentially Violent Individuals can Be Identified by STAMP System 2Health News:Potentially Violent Individuals can Be Identified by STAMP System 3Health News:Insecurity Jepardising WFP Initiatives in Western Afghanistan 2
(Date:1/15/2014)... BOSTON , Jan. 15, 2014 Tegra Medical is ... Mark King as its new Chief Executive Officer.  Mark ... in which he has overseen the company,s four facilities in ... and Costa Rica.  Mr. King joined Tegra Medical in 2012 ...
(Date:1/15/2014)... 15, 2014 The Cadence Fitness & Health Center ... the Medical Fitness Association, a non-profit organization assisting medically ... potential. The Cadence Fitness & Health Center is the ... second in the Chicagoland area. "The certification ...
(Date:1/15/2014)... 15, 2014 Reportlinker.com announces that a ... its catalogue: PharmaPoint: ... Market Analysis to 2022 ... - India Drug Forecast and Market Analysis ...
Breaking Medicine Technology:Tegra Medical Appoints New Chief Executive Officer 2Tegra Medical Appoints New Chief Executive Officer 3Cadence Fitness & Health Center Certified as Medical Fitness Facility 2Cadence Fitness & Health Center Certified as Medical Fitness Facility 3PharmaPoint: Atopic Dermatitis - India Drug Forecast and Market Analysis to 2022 2PharmaPoint: Atopic Dermatitis - India Drug Forecast and Market Analysis to 2022 3PharmaPoint: Atopic Dermatitis - India Drug Forecast and Market Analysis to 2022 4PharmaPoint: Atopic Dermatitis - India Drug Forecast and Market Analysis to 2022 5
... Hill-Rom Holdings, Inc., (NYSE: HRC ) ... the Credit Suisse,s 2011 Healthcare Conference in Phoenix on ... You are invited to listen to the live discussion ... access it directly at http://cc.talkpoint.com/cred001/110911a_ah/?entity=1_CIKQF3F .  A recorded ...
... 2011 Seven Summits Research issues critical PriceWatch Alerts for ... what our analysts have discovered about these stocks read the ... (Note: You may have to copy this link into your ... Alerts cover the following stocks: Intel Corporation (Nasdaq: ...
Cached Medicine Technology:Critical Alerts For Intel, Mosaic, Deckers, Foot Locker, and Jazz Pharmaceuticals Released By Seven Summits Research 2
With the Symphony family of Pacemakers, Ela presents the most advanced technology on the market. Symphony, lighter than a passport, will take your patients further, offering fast follow-up, using new...
Gentle curve facilitates less traumatic removal from eye. Increased length ideal for myopic eyes...
Sleeve extends 3mm beyond end, .90mm (20G) probe, 1.4mm (17G) sleeve...
Ideal for short scleral tunnel and trabecular meshwork incisions...
Medicine Products: