Navigation Links
Experimental Weight-Loss Drug Seems to Work: Study
Date:4/11/2011

By Steven Reinberg
HealthDay Reporter

SUNDAY, April 10 (HealthDay News) -- Obese patients taking a high dose of an investigational weight-loss pill called Qnexa lost an average of 22 pounds over a year, while also lowering their cholesterol and blood pressure numbers, a new study has found.

Qnexa is a combination of two medications: phentermine, the most widely used weight-loss drug in the United States, currently available under a variety of brand names as well as a generic; and topiramate (Topamax), best known as a drug used to ease epilepsy and migraine.

Qnexa was recently turned down as a weight-loss aid by the U.S. Food and Drug Administration, because there was not enough data on the risk of birth defects and heart problems related to the drug. Topiramate has been linked to an increased risk for cleft lip/palate in babies born to women who took the drug.

The results of the new study, which was funded by Vivus, Qnexa's maker, suggest that "the combination of topiramate and phentermine when administered with some lifestyle counseling could be a valuable treatment for obesity," said lead researcher Dr. Kishore Gadde, an assistant professor of psychiatry and director of the obesity clinical trials program at Duke University Medical Center.

One reason for the significant weight-loss is that these drugs work by different mechanisms, Gadde said. "In a treatment, [with] the more mechanisms you have there is a greater likelihood of achieving the kind of weight loss we are hoping for, in a large proportion of patients," he said.

In addition, the combination of drugs may alter the side effect profile for each drug, he speculated. "The thinking behind the combination of the drugs is that some of the side effects could actually cancel out," Gadde said. "Topiramate causes fatigue, and phentermine is a stimulant, so they could be negating the side effects of each other."

Topiramate can also cause
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3 4

Related medicine news :

1. Experimental drug achieves unprecedented weight loss
2. Science at a glance: Symposia, research and special events at Experimental Biology 2011
3. A new experimental diagnostic test able to quickly distinguish infection from tuberculosis disease
4. Extra Tests Not a Deterrent to Experimental Cancer Therapy
5. 2 Experimental Drugs Show Promise for Rare Pancreatic Cancer
6. Experimental approach may improve healing of diabetic wounds and bed sores
7. Study raises safety concerns about experimental cancer approach
8. First liver transplant patients receive experimental drug to prevent hepatitis C infection
9. Experimental Drug Helps Fight Aggressive Breast Cancer: Report
10. Experimental drug more potent, longer lasting than morphine
11. Experimental vaccine sets sights on lung cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Experimental Weight-Loss Drug Seems to Work: Study
(Date:11/28/2014)... A newly released article from ... the influenza virus that will soon be spreading across the ... article begins with a brief explanation of what the influenza ... families that children under the age of 5, adults over ... such as heart and lung diseases, asthma, or diabetes, are ...
(Date:11/28/2014)... Georgia (PRWEB) November 28, 2014 Patten ... and locally grown. With those passions driving them, they've ... Georgia Grown. Having tried other pecans oils, they've found ... Pitts, Georgia to be exceptionally flavorful, retaining the buttery ... The same nutritional benefits found in pecans ...
(Date:11/28/2014)... Schools like Centra Rivermont understand the therapeutic and ... to its students. That is why the Virginia ... structure at its mental health services facility in ... for children who are identified as needing additional ... served the needs of children with severe emotional ...
(Date:11/28/2014)... talklocal ( http://www.talklocal.com ) is launching in ... by phone in about 90 seconds. , The launch ... reported to have touched down just north of the city ... tornadoes, Denver residents now know all too well the value ... having local pros in over 50 service categories on speed ...
(Date:11/28/2014)... 2014 Nipomo Family Dentistry , ... recently opened its doors at 195 N. Thompson St., ... preventative care like teeth cleanings, oral exams, fillings, implants ... teeth whitening (and Kor whitening), laser whitening, gum tissue ... Family Dentistry’s five-person team also takes a philanthropic approach ...
Breaking Medicine News(10 mins):Health News:How Flu Vaccines Can Impact Families Is Discussed in New Article from Community Health Center of Snohomish County 2Health News:Patten Pecans Goes Local with Nutritious Georgia Pecan Oil 2Health News:Centra Rivermont (VA) Provides School Playground Equipment from APCPLAY© for Special Needs Students 2Health News:Centra Rivermont (VA) Provides School Playground Equipment from APCPLAY© for Special Needs Students 3Health News:TalkLocal Launches In Denver A Week After Multiple Tornadoes Hit Near City 2Health News:Nipomo Family Dentistry Opens New Dental Office in Nipomo 2Health News:Nipomo Family Dentistry Opens New Dental Office in Nipomo 3
... 1 Oral Session and 21 Poster Sessions ... Debuts New Clostridium difficile Program , LOUISVILLE, Colo., ... today that it will be presenting 21 posters,highlighting three ... Antimicrobial Agents and Chemotherapy (ICAAC) held at the,McCormick Place ...
... Centers to Offer Free Health Assessments, HARRISBURG, Pa., ... invited Pennsylvanians to take advantage of,free health assessments being ... Sept. 21. The free health services are available in,conjunction ... which is observed on,Sept. 18., "Nearly 800,000 Pennsylvanians ...
... to Lead Financing Strategies to Fund Growth, ... Bulletin Board: APHY) today announced that it has ... EFH ) to develop and,lead financing strategies. Assured ... for patients with chronic pain and other,long-term care ...
... strengthen brand recognition, national ... BUFFALO, N.Y., Sept. 17 Meritain Health, ... today announced,the name change of recently acquired benefits ... of Meritain Health. Meritain Health acquired Weyco ...
... 17 LifeNet Health, a leading,biomedical and allograft ... Wound Allograft Institute" in affiliation with The Living ... and most progressive,organ and tissue recovery organizations in ... Institute" will directly serve the needs of burn,patients ...
... asthma type, study concludes, , , MONDAY, Sept. 17 ... the type of asthma you develop, new research ... in affluent, developed countries had more allergy-triggered asthma ... countries. , "The link between atopic sensitization ...
Cached Medicine News:Health News:Replidyne Pipeline Featured at 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy 2Health News:Replidyne Pipeline Featured at 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy 3Health News:Replidyne Pipeline Featured at 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy 4Health News:Replidyne Pipeline Featured at 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy 5Health News:Assured Pharmacy Retains Empire Financial Group 2Health News:Assured Pharmacy Retains Empire Financial Group 3Health News:Meritain Health Announces Name Change for Acquired Companies 2Health News:LifeNet Health Establishes 'The Skin & Wound Allograft Institute' 2Health News:Allergy-Induced Asthma More Common in Affluent Countries 2Health News:Allergy-Induced Asthma More Common in Affluent Countries 3
(Date:11/26/2014)... 2014 Investor-Edge has initiated coverage on ... Horizon Pharma PLC (NASDAQ: HZNP ), Endocyte Inc. ... JNJ ), and Theravance Inc. (NASDAQ: THRX ... at: http://investor-edge.com/register . On Tuesday, November 25, ... Dow Jones Industrial Average edged 0.02% lower, to finish the ...
(Date:11/26/2014)... Pa. , Nov. 26, 2014 ... to the development of innovative transdermal synthetic cannabinoid treatments, ... Piper Jaffray 26th Annual Healthcare Conference 2014. The conference ... New York Palace in New York ... will present at 4:50 pm on Tuesday, December 2. ...
(Date:11/26/2014)... and LONDON , Nov. ... market intelligence, MarketResearch.com is pleased to announce the distribution ... Consultancy focusing on the active pharmaceutical ingredient (API) market. ... http://www.marketresearch.com/land/publisher.asp?vendorid=4023&progid=86891 . In IQ4I,s newest ... Forecast to 2020 , IQ4I analysts ...
Breaking Medicine Technology:Pharma Stocks Highlight - VIVUS, Horizon Pharma, Endocyte, Johnson and Johnson, and Theravance 2Pharma Stocks Highlight - VIVUS, Horizon Pharma, Endocyte, Johnson and Johnson, and Theravance 3Pharma Stocks Highlight - VIVUS, Horizon Pharma, Endocyte, Johnson and Johnson, and Theravance 4Pharma Stocks Highlight - VIVUS, Horizon Pharma, Endocyte, Johnson and Johnson, and Theravance 5Zynerba Pharmaceuticals to Present at Piper Jaffray 26th Annual Healthcare Conference 2014 2MarketResearch.com: Active Pharmaceutical Ingredient Market to Reach $175 Billion by 2020 Says IQ4I Report 2MarketResearch.com: Active Pharmaceutical Ingredient Market to Reach $175 Billion by 2020 Says IQ4I Report 3
... Biotechnology Company updates progress and upcoming,milestones on ... 2007 /PRNewswire-FirstCall/ - SemBioSys,Genetics Inc. , a ... for metabolic and cardiovascular disease,today announced positive ... human insulin. The Company,presented its findings at ...
... Tolerability Profile,in Subjects with Type 2 Diabetes ... /PRNewswire-FirstCall/ -- Phase III data,presented this week ... Diabetes,Association demonstrated that saxagliptin, an inhibitor of,dipeptidyl-peptidase-4 ... BMY) and AstraZeneca (NYSE: AZN), in,combination with ...
Cached Medicine Technology:SemBioSys Presents Positive Insulin Data at the American Diabetes,Association Conference 2SemBioSys Presents Positive Insulin Data at the American Diabetes,Association Conference 3SemBioSys Presents Positive Insulin Data at the American Diabetes,Association Conference 4Data Demonstrated Saxagliptin Added to Metformin Improved Glycemic,Control in Subjects with Type 2 Diabetes Compared to Metformin,Alone 2Data Demonstrated Saxagliptin Added to Metformin Improved Glycemic,Control in Subjects with Type 2 Diabetes Compared to Metformin,Alone 3Data Demonstrated Saxagliptin Added to Metformin Improved Glycemic,Control in Subjects with Type 2 Diabetes Compared to Metformin,Alone 4Data Demonstrated Saxagliptin Added to Metformin Improved Glycemic,Control in Subjects with Type 2 Diabetes Compared to Metformin,Alone 5Data Demonstrated Saxagliptin Added to Metformin Improved Glycemic,Control in Subjects with Type 2 Diabetes Compared to Metformin,Alone 6
... Gellhorn Pessary is used for ... prolapse, or procidentia. It has ... and comes in nine sizes. ... easily folds over for insertion, ...
... are among the smallest and ... with advanced reporting software that ... information. Extensive testing by independent ... accuracy, making it widely recognized ...
Low Profile Design for Precise Anchor Placement...
... is a minimally invasive treatment option ... urinary incontinence (SUI). The Monarc treats ... abdominal stress events, such as sneezing, ... approach avoids the retropubic space.Monarc's transobturator ...
Medicine Products: