Navigation Links
Experimental Vaccine Shows Promise for Lung Cancer: Study
Date:10/24/2011

MONDAY, Oct. 24 (HealthDay News) -- New research suggests that physicians may be able to strengthen the power of chemotherapy in patients with the most common form of lung cancer by adding a cancer vaccine to the treatment.

The combined treatment for non-small cell lung cancer was tested in a phase 2 study and still has to go through more research, as experimental drugs go through three phases of study. Although the rate of serious side effects was somewhat higher in those who received both treatments compared to chemotherapy alone, this new approach seems feasible, the study authors said.

Commenting on the study, Srikumar Chellappan, chair of the department of tumor biology and scientific director of the National Functional Genomics Center at H. Lee Moffitt Cancer Center and Research Institute in Tampa, Fla., said that the research is promising and the treatment could become a new strategy.

Chellappan, who was not involved with the study but is familiar with the findings, noted there are caveats. "It should be pointed out that the increases in overall survival and progression-free survival are not dramatic, but any increase is very welcome, considering that the patients are in an advanced stage of cancer."

Patients with advanced non-small cell lung cancer have very low survival rates because of the spread of cancer to various organs in the body, such as the brain, Chellappan noted.

Currently, patients with advanced disease are treated with chemotherapy. In the study, published online Oct. 22 in The Lancet Oncology, Elisabeth Quoix from the University of Strasbourg in France and colleagues assigned 148 patients in the advanced stages of non-small cell lung cancer to either receive the experimental cancer vaccine called TG4014 in combination with chemotherapy or receive chemotherapy alone.

After six months, the cancer in 43 percent of those given the combination treatment hadn't progressed compared to 35 percent of those who took chemotherapy alone. The combo treatment was especially beneficial in a subgroup of patients who had a normal number of a type of immune response cells called "natural killer cells" upon entering the study, the researchers noted in a journal news release.

The rate of serious side effects was 52 percent in those given the combo treatment and 47 percent in those who received chemotherapy alone.

Non-small cell lung cancer is the number one cause of cancer death worldwide, and nearly half of these patients already have advanced disease by the time they are diagnosed, the authors noted in the news release.

More information

For more about lung cancer, visit the U.S. National Library of Medicine.

-- Randy Dotinga

SOURCES: Srikumar Chellappan, Ph.D., chair, department of tumor biology and scientific director, National Functional Genomics Center, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Fla.; Oct. 22, 2011, The Lancet Oncology, online


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Experimental Drug Offers Hope for Cystic Fibrosis Patients
2. Experimental Vaccine Shields Monkeys Against Ebola
3. Experimental targeted therapy shows early promise against medulloblastomas
4. Experimental nonsteroidal treatment of asthma shows promise
5. Experimental obesity drug avoids brain effects that troubled predecessors
6. Experimental treatments for cocaine addiction may prevent relapse
7. Experimental TB Test Called Fast and Accurate
8. Experimental Drug Shows Promise for Bone Marrow Disorder
9. Experimental Leukemia Drug Proves a Slam Dunk
10. Experimental Test May Spot Prostate Cancer Earlier, More Accurately
11. Experimental Drug Aids Kids With Nervous System Tumor
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Experimental Vaccine Shows Promise for Lung Cancer: Study 
(Date:4/28/2017)... (PRWEB) , ... April 28, 2017 , ... ... announce that Aditya Patel M.D. has joined the revolutionary endoscopic practice under Dr. ... board certification in Interventional Pain Medicine. The patented, revolutionary eDiscSculpt Technique created and ...
(Date:4/28/2017)... ... April 28, 2017 , ... The Texas Cord Blood Bank (TCBB), a ... and delivery team at Women’s Hospital at Renaissance in Edinburg for their outstanding efforts ... hospital and decide to donate. , “Women’s Hospital at Renaissance has been a ...
(Date:4/28/2017)... Yorba Linda, Ca (PRWEB) , ... April 28, ... ... entities with cardiac or hERG liability could substantially improve drug safety and minimize ... will be provided for validating ion channel inhibition using cell lines and for ...
(Date:4/28/2017)... ... ... Bill Howe started his sewer and drain company in 1980 focusing heavily ... team, the Bill Howe brand was born and they began cultivating their mission to ... the San Diego community in which they worked, lived and were raising their daughters. ...
(Date:4/28/2017)... Pensacola, FL (PRWEB) , ... April 28, 2017 ... ... Tampa, Florida are conducting a pilot study of ActiGraph’s CentrePoint Data ... ActiGraph is a leading provider of clinical-grade wearable activity and sleep monitoring solutions ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... -- Research and Markets has announced the addition ... Analysis, Regional Outlook, Growth Trends, Key Players, Competitive Strategies and ... ... valued at US$ 7,167.6 Mn in 2015, and is expected ... CAGR of 5.6% from 2016 to 2024. ...
(Date:4/20/2017)... -- Research and Markets has announced the addition ... Analysis By Service (Manufacturing, Research), By Country, (Brazil, Mexico, Colombia, ... report to their offering. ... The Latin American pharmaceutical contract manufacturing services market is ... Low drug registration cost in Latin American countries and continuous ...
(Date:4/19/2017)... The Mobile X-Ray product segment is the most ... the forecast period Mobile X-Ray segment is the ... X-Ray devices market, which is estimated to be valued at ... CAGR of 7% over the forecast period. Mobile X-Ray segment ... US$ 100 Mn in 2017 over 2016. The segment,s revenue ...
Breaking Medicine Technology: