Navigation Links
Experimental Drug Suppresses Appetite in Mice: Study
Date:7/26/2012

THURSDAY, July 26 (HealthDay News) -- An experimental drug tested in mice might one day help people lose weight and keep it off long-term, according to researchers.

The drug, called JD5037, increases sensitivity to the hormone leptin, a natural appetite suppressant found in the body, according to a study in the July 26 issue of the journal Cell Metabolism.

"By sensitizing the body to naturally occurring leptin, the new drug could not only promote weight loss, but also help maintain it," senior study author George Kunos, of the U.S. National Institute on Alcohol Abuse and Alcoholism, said in a journal news release. "This finding bodes well for the development of a new class of compounds for the treatment of obesity and its metabolic consequences."

Leptin supplements alone are not effective at helping people lose excess weight, according to the release. It's believed that this is due to desensitization to leptin, which means that the body can no longer respond to leptin.

In this study, the researchers found that JD5037 suppressed the appetite of obese mice and led to weight loss, in part by resensitizing the mice to leptin.

Scientists note, however, that research with animals often fails to provide similar results in humans.

"Obesity is a growing public health problem, and there is a strong need for new types of medications to treat obesity and its serious metabolic complications, including diabetes and fatty liver disease," Kunos said.

More information

The U.S. National Institute of Diabetes and Digestive and Kidney Diseases offers tips on safe and effective weight-loss programs.

-- Robert Preidt

SOURCE: Cell Metabolism, news release, July 26, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Experimental Chemo Combo for Colon Cancer Disappoints
2. Experimental Pill for Multiple Sclerosis Shows Promise
3. Experimental Gel May Help Those With Advanced Parkinsons
4. Experimental Drug Eases Autistic Behaviors in Mice
5. Experimental Drug Helps Fight Some Childhood Cancers, Study Finds
6. Experimental drug improves muscle strength among male cancer patients
7. Experimental Vaccine Seems to Stop Nicotine Addiction in Mice
8. Content Writing King Announces Cancellation Of Experimental Video Creation Process For Their Article Marketing Website
9. Fertility preservation with cryopreservation of ovarian tissue: from experimental to mainstream
10. Experimental drug may extend therapeutic window for stroke
11. Experimental Chemical Helps Blind Mice See
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Experimental Drug Suppresses Appetite in Mice: Study
(Date:7/13/2014)... A Xarelto lawsuit webpage has been launched ... with the most current information regarding serious internal bleeding ... as well as the growing number of Xarelto ... The law firm is now offering free legal evaluations ... bleeding and related complications while using Xarelto, including:, ...
(Date:7/13/2014)... (PRWEB) July 13, 2014 According to ... this is a comprehensive program that teaches people how ... peripheral neuropathy without medications. This program also provides ... symptoms of peripheral neuropathy , including numbness, prickling, burning, ... its review that this home treatment program can help ...
(Date:7/12/2014)... Recently, iFitDress.com, one of the world’s leading ... red evening gowns . What’s more, all these hot outfits ... The company’s senior spokesman states, “We are proud to announce ... is an enjoyable shopping experience. In addition to the big ... low prices do not always mean bad quality. All the ...
(Date:7/12/2014)... 12, 2014 The report, "Phthalic Anhydride ... Market by Application & Geography – Trends & Forecast ... analysis and forecasting of market volume and value. The ... derivatives separately. The market of phthalic anhydride is projected ... to $8,415.89 million by 2018, with a CAGR of ...
(Date:7/12/2014)... July 12, 2014 The Security Analytics ... 2013 to $3,376.6 million by 2019, at an expected ... 2019. The challenges to counter the increasing number of ... of outdated cyber defense systems in organizations are enormous. ... and remodeling their existing architecture to develop better and ...
Breaking Medicine News(10 mins):Health News:Xeralto Lawsuit Page Launched By Wright & Schulte LLC To Provide Information On Potential For Xarelto Bleeding Side Effects, Growing Litigation 2Health News:Xeralto Lawsuit Page Launched By Wright & Schulte LLC To Provide Information On Potential For Xarelto Bleeding Side Effects, Growing Litigation 3Health News:Xeralto Lawsuit Page Launched By Wright & Schulte LLC To Provide Information On Potential For Xarelto Bleeding Side Effects, Growing Litigation 4Health News:The Peripheral Neuropathy Program Review Exposes Randall Labrum's Peripheral Neuropathy Treatment Program – Vkool.com 2Health News:The Peripheral Neuropathy Program Review Exposes Randall Labrum's Peripheral Neuropathy Treatment Program – Vkool.com 3Health News:Discounted Red Evening Gown Announced by iFitDress.com 2Health News:Phthalic Anhydride Market Projected to Reach $8.42 Billion by 2018 – Report by MarketsandMarkets 2Health News:Phthalic Anhydride Market Projected to Reach $8.42 Billion by 2018 – Report by MarketsandMarkets 3Health News:Phthalic Anhydride Market Projected to Reach $8.42 Billion by 2018 – Report by MarketsandMarkets 4Health News:North America Security Analytics Market Worth $1,215.2 Million by 2019 - New Report by MicroMarket Monitor 2Health News:North America Security Analytics Market Worth $1,215.2 Million by 2019 - New Report by MicroMarket Monitor 3Health News:North America Security Analytics Market Worth $1,215.2 Million by 2019 - New Report by MicroMarket Monitor 4
... nearly 2 hours in the waiting room of the hospital, was ... ,Beatrice Vance, 49, died of a heart attack, but her death ... care that a reasonable person would have exercised in this situation.' ... Waukegan. A spokeswoman of that center refused to comment on the ...
... new backpack your son or daughter just got for the ... for a lifetime of back and neck ailments if not// ... of the Department of Occupational Therapy at University of the ... even they can’t take the day after day stress caused ...
... American inner city schoolgirls have been developing culturally ... measure// which children are likely to take offense ... the cartoons over traditional written descriptions of provocative ... Ph.D., a pediatric psychologist at The Children's Hospital ...
... and the American Society for Therapeutic Radiology and Oncology ... comes to// prostate cancer awareness, screening and their treatment ... cases of prostate cancer will be diagnosed in the ... screening for prostate cancer is relatively easy. ...
... to officials on Friday, a courthouse in New Jersey was ... the workers and it will remain shut at// least until ... of the woman’s medical condition, partly due to privacy rules. ... be critical. She is an independent title searcher with the ...
... new treatment for malaria has been developed with the help ... lives in Africa. A system based on fluid// replacement for ... College in London in collaboration with the Wellcome Trust Kenya ... lives of millions of kids, who die every year due ...
Cached Medicine News:Health News:Lighten Up! Heavy Backpacks a Weighty Load for Children to Bear 2Health News:Cartoons to Indicate Aggressiveness in Urban School Girls 2Health News:Cartoons to Indicate Aggressiveness in Urban School Girls 3Health News:Do You Know the Signs and Symptoms of Prostate Cancer? 2Health News:A Novel approach in Malaria treatment 2
(Date:7/11/2014)... , July 11, 2014  Kindred Hospital Houston ... announce the opening of its new outpatient wound ... services to people with chronic, hard to heal ... can lead to amputation, lower leg wounds related ... delayed closure, and traumatic injury wounds which are ...
(Date:7/11/2014)... 11, 2014 Research and Markets ( ... "Immunoprotein Diagnostic Testing Market - Forecasts to ... of 6% and is expected to be valued ... offering. http://photos.prnewswire.com/prnh/20130307/600769 ... has been segmented according to immunoprotein types which ...
(Date:7/10/2014)... 11, 2014  Major advances in radiation therapy ... being highlighted in a three-day Oncology Summit taking ... July, 2014.  Renowned national and international cancer experts from ... and exchange knowledge on modern technologies making treatment ... The Summit will address a ...
Breaking Medicine Technology:Kindred Hospital Houston Northwest, With Wound Care Specialists, Opens Outpatient Wound Healing And Hyperbaric Center 2Immunoprotein Diagnostic Testing Market - Forecasts to 2019: Expected to grow at the highest CAGR of 6% and is expected to be valued at USD 4,943.0 million 2Improving quality and access to advanced cancer care in India and South Asia 2Improving quality and access to advanced cancer care in India and South Asia 3Improving quality and access to advanced cancer care in India and South Asia 4Improving quality and access to advanced cancer care in India and South Asia 5
... CHEST 2007 on concomitant use of Perforomist(TM) Inhalation Solution with ... ... treatment-, NAPA, Calif., Oct. 24 Data presented today at,CHEST ... (ACCP), demonstrate concomitant use of nebulized formoterol,fumarate and tiotropium provided improved ...
... Two Major Clinical Studies TAX 323 and TAX ... Sanofi-aventis,announced today that results of two clinical studies ... cisplatin and,5- fluorouracil for induction therapy, significantly improved ... cell carcinoma of,the head and neck (SCCHN) are ...
Cached Medicine Technology:Clinical Trial Data on the Safety and Efficacy of Concomitant Formoterol Fumarate/ Tiotropium Treatment for COPD 2Clinical Trial Data on the Safety and Efficacy of Concomitant Formoterol Fumarate/ Tiotropium Treatment for COPD 3Clinical Trial Data on the Safety and Efficacy of Concomitant Formoterol Fumarate/ Tiotropium Treatment for COPD 4Clinical Trial Data on the Safety and Efficacy of Concomitant Formoterol Fumarate/ Tiotropium Treatment for COPD 5Clinical Trial Data on the Safety and Efficacy of Concomitant Formoterol Fumarate/ Tiotropium Treatment for COPD 6Studies Showing Significant Survival Improvement with Taxotere(R)-based Regimens in the Induction Treatment of Patients with Locally Advanced Head and Neck Cancer are Published in the Same Issue of the New England Journal of Medicine 2Studies Showing Significant Survival Improvement with Taxotere(R)-based Regimens in the Induction Treatment of Patients with Locally Advanced Head and Neck Cancer are Published in the Same Issue of the New England Journal of Medicine 3Studies Showing Significant Survival Improvement with Taxotere(R)-based Regimens in the Induction Treatment of Patients with Locally Advanced Head and Neck Cancer are Published in the Same Issue of the New England Journal of Medicine 4Studies Showing Significant Survival Improvement with Taxotere(R)-based Regimens in the Induction Treatment of Patients with Locally Advanced Head and Neck Cancer are Published in the Same Issue of the New England Journal of Medicine 5Studies Showing Significant Survival Improvement with Taxotere(R)-based Regimens in the Induction Treatment of Patients with Locally Advanced Head and Neck Cancer are Published in the Same Issue of the New England Journal of Medicine 6Studies Showing Significant Survival Improvement with Taxotere(R)-based Regimens in the Induction Treatment of Patients with Locally Advanced Head and Neck Cancer are Published in the Same Issue of the New England Journal of Medicine 7
Measles IgM ELISA test is an enzyme linked immunosorbent assay (ELISA) for the detection of IgG class antibodies to Measles (Rubeola) in human serum or plasma....
... The Diagnostic Automation, Inc.. (DAI) Measles ... for the detection and quantitative determination of ... human sera. Individual serum specimens may ... status. Paired sera, acute and convalescent, may ...
... osmolality at room temperature with the sample ... are cryoscopic artifacts due to high viscosity, ... with freezing point determinations. The superbly accurate ... osmometer has a much broader range of ...
... a glucocorticoid produced by the adrenal cortex ... is secreted with a circadian periodicity, and ... morning. Cortisol is often elevated in major ... AIDS, and in the visceral fat of ...
Medicine Products: