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Experimental Drug Shows Promise Against Cushing's Disease
Date:3/7/2012

ording to senior study author Dr. Beverly Biller, of Massachusetts General Hospital.

Cushing's patients already have difficulty processing glucose, she noted.

"Those patients who already were diabetic had the greatest increases in blood sugar, and those who were prediabetic were more likely to become diabetic than those who began with normal blood sugar," Biller said in the hospital news release. "So this is real and needs to be monitored carefully."

Mezitis agreed that careful patient monitoring is important. "Blood-sugar elevations are dose-dependent with pasireotide and will need to be managed as indicated for diabetes," he said.

More information

The U.S. National Institute of Diabetes and Digestive and Kidney Diseases has more about Cushing's syndrome.

-- Robert Preidt

SOURCES: Spyros Mezitis, M.D., endocrinologist, Lenox Hill Hospital, New York City; Massachusetts General Hospital, news release, March 7, 2012


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