Navigation Links
Experimental Drug Raises Good Cholesterol Levels in Early Trial
Date:11/17/2010

By Amanda Gardner
HealthDay Reporter

WEDNESDAY, Nov. 17 (HealthDay News) -- An experimental drug that raises HDL, or "good," cholesterol seems to have passed an initial hurdle by proving safe in preliminary trials.

Although the trial was primarily designed to look at safety, researchers scheduled to present the finding Wednesday at the American Heart Association's annual meeting in Chicago also report that anacetrapib raised HDL cholesterol by 138 percent and cut LDL, HDL's evil twin, almost in half.

"We saw very encouraging reductions in clinical events," said Dr. Christopher Cannon, lead author of the study, which also appears in the Nov. 18 issue of the New England Journal of Medicine.

A big study to confirm the results would take four to five years to complete so the drug is still years away from market, said Cannon, who is a cardiologist with Brigham and Women's Hospital in Boston.

Other experts are intrigued by the findings, but note that the research is still in very early stages.

"There are a lot of people in the prevention/lipid field that are simultaneously excited and leery," said Dr. Howard Weintraub, clinical director of the Center for the Prevention of Cardiovascular Disease at NYU Langone Medical Center in New York City.

Added Dr. John C. LaRosa, president of the State University of New York (SUNY) Downstate Medical Center in New York City: "It's very preliminary but it's important because the last drug out of the barrel of this type was not a success. This looks like a better drug, but it's not definitive by any means. Don't take this to the bank."

LaRosa was referring to torcetrapib, which, like anacetrapib, belongs to the class of drugs known as cholesterol ester transfer protein (CETP) inhibitors.

A large trial on torcetrapib was killed after investigators found an increased risk of death and other cardiovascular outcomes.

"I would be more excited [
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. UT Southwestern researchers create experimental vaccine against Alzheimers
2. Experimental Drug Aids Kids With Nervous System Tumor
3. Experimental Test May Spot Prostate Cancer Earlier, More Accurately
4. Experimental Leukemia Drug Proves a Slam Dunk
5. Experimental Drug Shows Promise for Bone Marrow Disorder
6. Experimental TB Test Called Fast and Accurate
7. Experimental treatments for cocaine addiction may prevent relapse
8. Experimental obesity drug avoids brain effects that troubled predecessors
9. Experimental nonsteroidal treatment of asthma shows promise
10. Experimental targeted therapy shows early promise against medulloblastomas
11. Experimental Vaccine Shields Monkeys Against Ebola
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Experimental Drug Raises Good Cholesterol Levels in Early Trial
(Date:7/22/2014)... 22, 2014 A Florida woman has ... that alleges the death of her husband was the ... thinner, Bernstein Liebhard LLP reports. According to her complaint, ... for the Southern District of Florida on June 23rd, ... suffered a subdural hemorrhage the following June. Despite emergency ...
(Date:7/22/2014)... HealthDay Reporter TUESDAY, July ... pregnancy may be more likely to have children with asthma ... that, compared with children born from mothers of normal weight, ... up to 20 to 30 percent higher odds of asthma," ... pediatrics at Children,s Hospital of Pittsburgh. Forno,s team also ...
(Date:7/22/2014)... 2014) The American Society of Hematology (ASH) will ... of Medicine, and Robert P. Hebbel, MD, of the ... Beutler Lecture and Prize for their significant research advances ... Ernest Beutler Lecture, named for the late Ernest Beutler, ... more than 50 years, is a two-part lectureship that ...
(Date:7/22/2014)... of the Clean Plate Club you eat pretty much ... A new Cornell University study shows that the average ... his or her plate. "If you put it ... Wansink Ph.D., author of the forthcoming book, Slim by Design, ... Brand Lab. , Wansink and co-author Katherine Abowd Johnson analyzed ...
(Date:7/22/2014)... disease, Dr. Ross Feldman says women are often in the ... men,s-only disease, however, data has shown that post-menopausal women are ... are less likely to be adequately diagnosed and treated. New ... British Journal of Clinical Pharmacology brings to light ... to identify which women are more prone to heart disease. ...
Breaking Medicine News(10 mins):Health News:Xarelto Lawsuit Filed by Florida Woman Alleges Uncontrollable Bleeding Led to Husband’s Death, Bernstein Liebhard LLP Reports 2Health News:Xarelto Lawsuit Filed by Florida Woman Alleges Uncontrollable Bleeding Led to Husband’s Death, Bernstein Liebhard LLP Reports 3Health News:Obesity During Pregnancy Linked to Raised Asthma Risk in Kids 2Health News:Obesity During Pregnancy Linked to Raised Asthma Risk in Kids 3Health News:Michael DeBaun, M.D., M.P.H., and Robert P. Hebbel, M.D., to present 2014 ASH Beutler Lecture 2Health News:Michael DeBaun, M.D., M.P.H., and Robert P. Hebbel, M.D., to present 2014 ASH Beutler Lecture 3Health News:Michael DeBaun, M.D., M.P.H., and Robert P. Hebbel, M.D., to present 2014 ASH Beutler Lecture 4Health News:Gene variant identified as a heart disease risk factor for women 2
... February issue of PNAS that understanding and treating cholesterol-related ... discovery of a receptor in the cells of mice ... during a study of cerebrotendinous xanthomatosis (CTX), a rare ... They said that Pregnane X receptor (PXR)// is present ...
... curvature of the spine diagnosed after the age ten, ... to earlier belief that the condition increases mortality rates ... related to the curvature. Researchers from the University of ... with LIS appear to experience only little physical// impairment ...
... to be launched by researchers from the UK and Netherlands ... with cancer. The research will be led by Dr. Julian ... Dr. René Bernards of the Netherlands Cancer Institute. This research ... and will have scientists looking at nearly 10,000 genes, inactivating ...
... journal, Cancer Cell reported that scientists have discovered why some ... others. Researchers have found that high levels of a specific ... drugs such as Taxol, which are used to treat a ... the// researchers focused on a molecule called AURORA-A which is ...
... has shown that those who smoke face the highest ... However, researchers added that more studies are needed before ... of cross-sectional data obtained from the US National Household ... from 1994 to 1996) was conducted. A total// of ...
... from the Department of Human Services at the University ... elevated levels of abdominal visceral fat are associated with ... was also found to be a primary determinant in ... investigators assessed// plasma lipids and lipoproteins and their relationships ...
Cached Medicine News:Health News:Cancer gene mystery to be cracked! 2
(Date:7/22/2014)...  Decision Resources Group finds that the market for interventional ... remain relatively stagnant at a value of around $80 million ... intervention (PCI) volumes are growing faster in Canada ... the United States and Europe ... increase in penetration of PCI procedures relative to coronary artery ...
(Date:7/22/2014)... According to a new ... (Technology Types - Near infrared (NIR) spectroscopy, Raman spectroscopy and ... Size, Share, Growth, Trends and Forecast, 2013 - 2019," the ... is expected to grow at a CAGR of 7.4% from ... was the largest contributor to global process spectroscopy market ...
(Date:7/22/2014)... , July 22, 2014  Eyeon Therapeutics has received ... treatment based on a charged hydrophilic polymer developed at ... has been shown to be safe and effective in ... MD, CEO states, "This first set of claims around ... way to moving this technology into the commercial phase.  ...
Breaking Medicine Technology:The Canadian Interventional Cardiology Device Market Will Remain Relatively Stagnant Through 2022 at Around $80 Million 2The Canadian Interventional Cardiology Device Market Will Remain Relatively Stagnant Through 2022 at Around $80 Million 3Process Spectroscopy Market Expected to Reach USD 1,179.6 Million in 2019: Transparency Market Research 2Process Spectroscopy Market Expected to Reach USD 1,179.6 Million in 2019: Transparency Market Research 3Process Spectroscopy Market Expected to Reach USD 1,179.6 Million in 2019: Transparency Market Research 4Particle Sciences and Eyeon Therapeutics Receive Patent on Novel Dry Eye Technology 2
... 12, 2011 Arena Pharmaceuticals, Inc. (NASDAQ: ARNA ... on August 29, 2011, as Vice President, Finance and Chief ... Arena for over 13 years before departing in March to ... a valuable leader who has been a key contributor to ...
... 2011 5 modules - 2 weeks - ... to announce that the Stability Testing Online Training Course is proving ... ,The secret behind the Stability testing Online Training Course ... is its user-friendly format which allows flexible and interactive high standard, ...
Cached Medicine Technology:Robert Hoffman to Rejoin Arena Pharmaceuticals as Vice President, Finance and Chief Financial Officer 2Robert Hoffman to Rejoin Arena Pharmaceuticals as Vice President, Finance and Chief Financial Officer 3Stability Testing Course is Taking the Online Training Format by Storm! 2
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: