Navigation Links
Experimental Drug Promising Against Tough-to-Treat Asthma
Date:8/3/2011

By Amanda Gardner
HealthDay Reporter

WEDNESDAY, Aug. 3 (HealthDay News) -- A new experimental drug for adults with asthma seems to improve lung function in patients who haven't been helped with standard steroids.

The drug, lebrikizumab, targets a specific receptor involved in asthma, and appears to be the first drug to be successful in this particular approach, said Dr. Steve Georas, a professor of medicine in the pulmonary and critical care division at the University of Rochester Medical Center.

It is also perhaps the first drug to have this specific effect in asthmatics, and may lead to more gains in individualized treatments for patients.

"Personalized medicine hasn't made huge strides in asthma," said Georas. "We're all hopeful we're on the verge of a new era in that regard. This appears to be a first tentative step in that direction."

Georas was not involved with the new research, which appears in the Aug. 3 issue of the New England Journal of Medicine and was funded by Genentech, which makes lebrikizumab.

Lebrikizumab is a monoclonal antibody that binds to interleukin-13 (IL-13), a signaling molecule involved in the inflammatory responses associated with asthma.

Although glucocorticoids also inhibit IL-13, the molecule manages to exert its influence in other ways which, so far, have eluded current medications. But, lebrikizumab works in a different way than traditional steroids.

The authors randomized 219 adults who had not responded to standard treatments to receive either lebrikizumab or a placebo.

After three months, the overall group of patients taking lebrikizumab saw a 5.5 percent improvement in their FEV1 (forced expiratory volume in one second), which measures how much a person expels when exhaling, compared to the placebo group.

Patients who had high IL-13 levels (as measured by the protein periostin, which is produced by IL-13) saw an FEV1 improvement o
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. University Hospitals Case Medical Center to begin clinical trial on experimental anti-TB drug
2. Experimental Drug Might Help Fight Alzheimers After All
3. Experimental Drug Bests Chemo in Non-Small Cell Lung Cancer Study
4. Experimental Vaccine Seems to Cure Prostate Cancer in Mice
5. ASCO: Experimental vaccine made from frozen immune cells shows promise for prostate cancer patients
6. Ex-Dallas Maverick survives rare form of leukemia thanks to experimental drug treatment
7. Experimental treatment offers relief from painful prostate condition
8. Christos Mantzoros honored by Federation of the American Societies for Experimental Biology
9. Experimental Test May Warn of Premature Births
10. Experts at Experimental Biology examine dietary cholesterol, egg intake and heart disease risk
11. Experimental Weight-Loss Drug Seems to Work: Study
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Experimental Drug Promising Against Tough-to-Treat Asthma
(Date:7/14/2014)... 2014 According to the ... recently updated by Vkool.com, this is a ... range of simple and easy tips for ...     Increasing omega-3 fatty acids ... ,     Increasing fiber ,     Avoid ...
(Date:7/14/2014)... 14, 2014 Vaginal Mesh lawsuit ... seven different pelvic mesh manufacturers in the U.S. District ... Schulte LLC. The federal complaints are pending against pelvic ... American Medical Systems (MDL No. 2325), and C.R. Bard, ... are 58,262 Vaginal Mesh lawsuit claims pending, according to ...
(Date:7/14/2014)... July 14, 2014 Doctor Mike Hamilton ... launch of their new company website. The Inception website ... information on chiropractic marketing. It's also a place for ... has to offer. , When contacted at his office, ... version of our main website. Our site is obviously ...
(Date:7/14/2014)... Texas (PRWEB) July 14, 2014 ... forefront in complete spine care—from diagnosis to treatment and ... locations are either certified in or training for certification ... Theresa Adame, have recently completed the extensive program. , ... utilizing The McKenzie Method results in better outcomes for ...
(Date:7/14/2014)... Sacramento, CA (PRWEB) July 14, 2014 ... a new office in Sacramento. The announcement has been made ... the office. In addition, the announcement has been made in ... their dental services in the Sacramento area. , Crystal Dental ... procedures. Some of the services offered by Crystal Dental include ...
Breaking Medicine News(10 mins):Health News:Endometriosis Bible and Violet Protocol Book Review Exposes Zoe Brown's Endometriosis Treatment Guide – Vkool.com 2Health News:Endometriosis Bible and Violet Protocol Book Review Exposes Zoe Brown's Endometriosis Treatment Guide – Vkool.com 3Health News:Nearly 60,000 Vaginal Mesh Lawsuit Claims Filed Against Seven Different Pelvic Mesh Manufacturers 2Health News:Nearly 60,000 Vaginal Mesh Lawsuit Claims Filed Against Seven Different Pelvic Mesh Manufacturers 3Health News:Nearly 60,000 Vaginal Mesh Lawsuit Claims Filed Against Seven Different Pelvic Mesh Manufacturers 4Health News:Nearly 60,000 Vaginal Mesh Lawsuit Claims Filed Against Seven Different Pelvic Mesh Manufacturers 5Health News:Doctor Mike Hamilton From Inception Chiropractic Websites Announces the Launch of Their New Website 2Health News:Spine Team Texas’ Physical Therapists Complete The McKenzie Method Training and Certification 2Health News:Spine Team Texas’ Physical Therapists Complete The McKenzie Method Training and Certification 3Health News:Crystal Dental Announces the Opening of New Office Location in Sacramento 2
... May 29 The following is a,statement by Matthew ... World Health Organization,s World No Tobacco Day, to be ... toll of the global,tobacco epidemic and the urgent need ... and save lives., This year,s theme -- Tobacco-Free ...
... Area ... hospitals, PLANO, Texas, May ... in Chicago,Illinois, has extended its relationship with the global information,technology provider. Perot ... ago, and in that period of,time its team of revenue cycle professionals ...
... Alseres,Pharmaceuticals, Inc. (Nasdaq: ALSE ) today ... of Stockholders Thursday, June 12, 2008 at 1:00,p.m. ... Hale & Dorr, 60 State,Street, Boston, MA., ... Pharmaceuticals, Inc., Alseres Pharmaceuticals, Inc. (ALSE) is ...
... patients who suffer a heart attack never have any warning ... problem is noncalcified plaque, a buildup of soft deposits embedded ... angiography or cardiac stress tests and prone to rupture ... success in detecting and measuring noncalcified plaque. In a pilot ...
... University Massey Cancer Center researchers have identified that a ... chronic myelogenous leukemia cells previously resistant to conventional forms ... a cancer of the bone marrow caused by a ... common forms of leukemia. Imatinib mesylate, or Gleevec, is ...
... N.J., May 29 The Musculoskeletal Transplant,Foundation (MTF) ... needed for cartilage and joint repair for injured ... be given priority in obtaining,tissue used for cartilage ... in short supply, these types of tissue are ...
Cached Medicine News:Health News:World No Tobacco Day Sounds Urgent Call for Nations to Fight Tobacco Use, Save Lives 2Health News:World No Tobacco Day Sounds Urgent Call for Nations to Fight Tobacco Use, Save Lives 3Health News:Perot Systems and Sinai Health System Extend Revenue Cycle Solutions Contract 2Health News:Alseres Pharmaceuticals, Inc. Announces 2008 Annual Stockholders Meeting 2Health News:New method effective in detecting dangerous coronary plaque 2Health News:New method effective in detecting dangerous coronary plaque 3Health News:Combination of 2 novel anti-cancer agents may help fight CML resistant to current therapy 2
(Date:7/11/2014)... July 11, 2014 Neurelis, Inc. ("Neurelis") today ... end the option held by Biotie to purchase Neurelis, ... of NRL-1 (intranasal diazepam) for pediatric and adult epilepsy ... the past year, Biotie has advanced the development program ... the pivotal clinical work required for NDA submission to ...
(Date:7/10/2014)... 10, 2014  Breg, Inc., a premier provider ... the FreeRunner™ knee brace with new innovations to ... mal-tracking return to active lifestyles.  FreeRunner,s patent-pending design ... providing support when patients need it most, and ... Patellofemoral issues are the most common ...
(Date:7/10/2014)... Utah , July 10, 2014  BC Technical, ... and MiE America , Inc., a leading provider ... entered into a long-term agreement naming BC Technical as ... US. MiE and BC Technical announced ... agreement to establish BC Technical as the service and ...
Breaking Medicine Technology:Neurelis Regains Rights to Intranasal Diazepam Program 2Neurelis Regains Rights to Intranasal Diazepam Program 3Breg Introduces Knee Brace to Help Runners with Patellofemoral Pain Syndrome 2BC Technical Partners With MiE America To Be Authorized Provider Of Systems & Service 2
... Sept. 12, 2011 International Isotopes Inc (OTC Bulletin Board: ... an update of the Company,s general business status, particularly, the ... well as to discuss progress of its ongoing plans for ... Isotopes Inc General Business Update. When: ...
... Lewis County today launched a new program to help ... Through a partnership with the National Association of Counties (NACo), ... a card that offers an average of 24 percent savings ... The card can be used by those who do not ...
Cached Medicine Technology:International Isotopes Inc Announces Conference Call to Give an Update on the Company's General Business Status 2Lewis County Introduces Prescription Discount Card to Help Alleviate High Costs 2
Full Handle Laseredge Spoon Blade Knife, 3.0 mm angled double bevel. Blade dimension: 11.0 mm (L) x 3.0 mm (W). Cut: 320....
Full Handle Laseredge Slit Blade Knife, 3.2 mm angled bevel up. Blade tip dimension: 14.4 mm x 3.2 mm x 3.7 mm....
Full Handle Laseredge Slit Blade Knife, 3.2 mm straight. Blade tip dimension: 14.4 mm x 3.2 mm x 3.7 mm....
Full Handle Laseredge Slit Blade Knife, 3.0 mm angled bevel up. Blade tip dimension: 14.4 mm x 3.0 mm x 3.7 mm....
Medicine Products: