Navigation Links
Experimental Drug Might Help Fight Alzheimer's After All
Date:7/20/2011

uild up of beta amyloid proteins, which accumulate as plaque, is responsible for Alzheimer's.

Salloway's study looked at the drug's safety in 194 Alzheimer's patients, most of whom had mild- to-moderate Alzheimer's and participated in a long-term (78 weeks or longer) study. Some of the participants were followed for four years or more.

Ninety-one percent of participants had side effects, about a quarter of which were attributable to bapineuzumab. Of these, 85 percent were mild or moderate.

The overall rate of vasogenic edema (water on the brain) was 9.3 percent, a number that decreased over time, said Salloway, a professor of neurology and psychiatry at Alpert Medical School of Brown University and director of the Butler Hospital Memory and Aging Program in Providence, R.I. The edema was symptomless in most cases, he said.

The other study, which involved looking at more than 2,000 MRI scans from 262 patients, found 36 cases of amyloid-related imaging abnormalities (ARIA) may have been linked to the bapineuzumab.

These imaging abnormalities may indicate inflammation of the brain caused by water retention.

But only 8 of those 36 cases involved symptoms, and they were more likely to be found in patients with APOE-e4 who were taking higher doses of the drug. The likelihood of these effects diminished with additional infusions of lower-dose bapineuzumab.

"There is a growing sense that VE [vasogenic edema] or ARIA [amyloid-related imaging abnormalities] is a manageable side effect and may actually be a sign that the drug is clearing amyloid from the brain and the blood vessels," said Salloway. "Treatment will require ongoing monitoring with MRI."

The researchers, who said monitoring of bapineuzumab will continue, are now awaiting the results of a larger Phase III trial on the drug.

Because this study was presented at a medical meeting, the data and conclusions should be viewed as preliminary until published in a pe
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Experimental Drug Bests Chemo in Non-Small Cell Lung Cancer Study
2. Experimental Vaccine Seems to Cure Prostate Cancer in Mice
3. ASCO: Experimental vaccine made from frozen immune cells shows promise for prostate cancer patients
4. Ex-Dallas Maverick survives rare form of leukemia thanks to experimental drug treatment
5. Experimental treatment offers relief from painful prostate condition
6. Christos Mantzoros honored by Federation of the American Societies for Experimental Biology
7. Experimental Test May Warn of Premature Births
8. Experts at Experimental Biology examine dietary cholesterol, egg intake and heart disease risk
9. Experimental Weight-Loss Drug Seems to Work: Study
10. Experimental drug achieves unprecedented weight loss
11. Science at a glance: Symposia, research and special events at Experimental Biology 2011
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Experimental Drug Might Help Fight Alzheimer's After All
(Date:12/19/2014)... December 19, 2014 Diet Doc strives ... current approach to weight loss by combining ... The professionals at the company understand that remaining committed ... effects of eliminating carbohydrates and sugars from the diet ... to abandon their weight loss goals. , For ...
(Date:12/19/2014)... December 19, 2014 B. E. Smith, ... healthcare providers, has been retained to lead a national ... Hospital in Franklin, Ind. The top executive search firm ... placed more than 900 healthcare executives into organizations. ... service hospital providing care to the residents of Johnson ...
(Date:12/19/2014)... (PRWEB) December 19, 2014 Hands On Mobile ... available. The Spa On Wheels has been transformed into ... from the outside world seems to disappear. The Virtual Tour ... massages, facials, spa parties, corporate events and more. , The ... Spa On Wheels which is actually an overhauled Winnebago. Marla ...
(Date:12/19/2014)... From November 24, 2014, Siddhi Yoga ... 2014 in its Goa retreat . This is the ... winters, from November to March, Siddhi Yoga will organize four ... Goa. The Goa training sessions will conclude in March 2015. ... training, the 10th intake is also a 200 YTT ...
(Date:12/19/2014)... 2014 This is a professional and ... Gliquidone industry with a focus on the Chinese market. ... of the Gliquidone manufacturers and is a valuable source ... in the industry. , Firstly, the report provides a ... and manufacturing technology. Then, the report explores the international ...
Breaking Medicine News(10 mins):Health News:Diet Doc Incorporates Appetite Zap into their Already Impressive Collection of Diet Products to Jump Start the Metabolism and Burn Fat 4X Faster 2Health News:Diet Doc Incorporates Appetite Zap into their Already Impressive Collection of Diet Products to Jump Start the Metabolism and Burn Fat 4X Faster 3Health News:Diet Doc Incorporates Appetite Zap into their Already Impressive Collection of Diet Products to Jump Start the Metabolism and Burn Fat 4X Faster 4Health News:Johnson Memorial Hospital Retains B. E. Smith to Recruit New Chief Financial Officer 2Health News:Johnson Memorial Hospital Retains B. E. Smith to Recruit New Chief Financial Officer 3Health News:A Virtual Tour Of Hands On Mobile Massage Spa Is Now Available 2Health News:A Virtual Tour Of Hands On Mobile Massage Spa Is Now Available 3Health News:Siddhi Yoga’s 10th intake of YTT started in Goa on November 24, 2014 2Health News:Siddhi Yoga’s 10th intake of YTT started in Goa on November 24, 2014 3Health News:Gliquidone Industry Global and China Analysis for 2019, Now Available at ReportsnReports.com 2Health News:Gliquidone Industry Global and China Analysis for 2019, Now Available at ReportsnReports.com 3Health News:Gliquidone Industry Global and China Analysis for 2019, Now Available at ReportsnReports.com 4Health News:Gliquidone Industry Global and China Analysis for 2019, Now Available at ReportsnReports.com 5Health News:Gliquidone Industry Global and China Analysis for 2019, Now Available at ReportsnReports.com 6
... in the Feb. 1 issue of the journal SLEEP ... obstructive sleep apnea (OSA) are largely explained by total sleep ... link between OSA severity and daytime sleepiness, measured by the ... for total sleep time. Neither sleep disturbances, measured by ...
... in the Feb. 1 issue of the journal SLEEP ... the longitudinal link between sleep problems and depression. Results of ... converse association was not found. These findings are consistent with ... children from the development of depression. , Results of ...
... a Menu Game PlanEL SEGUNDO, Calif., Jan. 31 ... for those diagnosed with chronic kidney disease (CKD) and ... the benefits of Super Bowl Sunday treats with kidney-friendly ... www.davita.com . Diet is an integral part of managing ...
... effects after rare disease surgery , , SATURDAY, Jan. 31 ... rare form of childhood brain cancer called ependymoma is ... , Ependymoma affects the central nervous system. Aggressive surgery ... limited the use of radiation therapy. , In this ...
... Practice Arm of the School,s Department of Forensic ... Jan. 30 The Chicago School of ... its psychology services to the legal sector and ... thanks to its new Forensic Center, which was ...
... CINCINNATI, Jan. 30 The Kroger Co. (NYSE: ... in its family of retail stores,because the product was associated ... be contaminated with Salmonella. , Stores ... operates,are included in this recall: Kroger, Ralphs, Fred Meyer, ...
Cached Medicine News:Health News:Daytime impairments in older men with obstructive sleep apnea are related to total sleep time 2Health News:Study finds genetic link between sleep disorders and depression in young children 2Health News:Study finds genetic link between sleep disorders and depression in young children 3Health News:DaVita.com Promotes Kidney-Friendly Foods for Super Bowl(R) XLIII 2Health News:DaVita.com Promotes Kidney-Friendly Foods for Super Bowl(R) XLIII 3Health News:Aggressive Treatment Effective in Kids' Brain Cancer 2Health News:New Chicago School of Professional Psychology Forensic Center Opens Doors to the Community 2Health News:New Chicago School of Professional Psychology Forensic Center Opens Doors to the Community 3Health News:Kroger Recalls Nut Topping Due to Possible Health Risk 2
(Date:12/17/2014)... , Dec. 17, 2014  IGI Laboratories, Inc. (NYSE ... closing of its offering of $125 million aggregate principal ... "Notes").  The Notes were offered and sold only to ... Securities Act of 1933, as amended (the "Securities Act"). ... rate of 3.75% per year, payable semiannually in arrears ...
(Date:12/17/2014)... and RALEIGH, N.C. , Dec. ... LLC (CTMC), and Integrated Clinical Trial Services, LLC ... retention for clinical trials announce that they have ... Marketing Services (i-CTMS). i-CTMS will provide a broad ... pharmaceutical, biotechnology and medical device companies. ...
(Date:12/15/2014)... Registreer nu via  http://bit.ly/ag8Sypm14de ... Februar sind alle akkreditierten pharmazeutischen Patientenversorgungsakten-Firmen (PMR) ... PROGRAMM ™ 2015 in Amsterdam ... Tagung soll dazu beitragen, der Aegate PMR ... profitablen Unternehmensdienstleistungen, die für Apotheken und die ...
Breaking Medicine Technology:IGI Laboratories Announces Closing of $125 Million of 3.75% Convertible Senior Notes Due 2019 2IGI Laboratories Announces Closing of $125 Million of 3.75% Convertible Senior Notes Due 2019 3IGI Laboratories Announces Closing of $125 Million of 3.75% Convertible Senior Notes Due 2019 4Integrated Clinical Trial Services and Clinical Trial Marketing Communications Form Joint Venture 2Integrated Clinical Trial Services and Clinical Trial Marketing Communications Form Joint Venture 3Symposium über Aegates Ecosystem-Partner-Programm für sichere Medikamente vom 19. - 20. Februar 2015 in Amsterdam 2
... , , , , FRAZER, Pa., Jan. ... that effective February 5, 2010, Robert P. Roche, Jr., Executive ... with the company to pursue other longstanding interests. During ... and marketing organization into a global business that exceeded $2 ...
... , SOUTH SAN FRANCISCO, Dec. 31 ... was unable to satisfy the closing conditions set forth in ... among Anesiva, Arca Acquisition Corporation, a wholly-owned subsidiary of Anesiva, ... and IX only of the agreement, each of the Arcion ...
Cached Medicine Technology:Cephalon Executive Vice President of Worldwide Pharmaceutical Operations Robert Roche to Resign Position 2Cephalon Executive Vice President of Worldwide Pharmaceutical Operations Robert Roche to Resign Position 3Cephalon Executive Vice President of Worldwide Pharmaceutical Operations Robert Roche to Resign Position 4Anesiva Announces Merger With Arcion Therapeutics Will Not be Completed 2
A compact mobile System Cart gives mobility within your department. The cart accomodates the Uromac Median data processor, desktop computer, printer and provides stowage space. Patient related transd...
... your expectations with state of the art ... customized to meet the needs of your ... can be upgraded to grow with you. ... database management, it is easy to see ...
... ease of use make the OM-5 Series ... for office or hospital-based urodynamics, the OM-5 ... leak point pressure, or urethral pressure profiles. ... the OM-5 flexible enough to meet the ...
... capabilities combined with ease of use make ... its class. Ideal for office or hospital-based ... for Uroflowmetry, cystometry, leak point pressure, or ... available which make the OM-5 flexible enough ...
Medicine Products: