Navigation Links
Experimental Drug Eases Autistic Behaviors in Mice
Date:4/25/2012

By Jenifer Goodwin
HealthDay Reporter

WEDNESDAY, April 25 (HealthDay News) -- An experimental drug reduced two signature characteristics of autism -- repetitive behavior and abnormal social interactions -- in laboratory mice, new research finds.

The drug, GRN-529, targets glutamate, a major neurotransmitter found throughout the brain that's involved with activating neurons, or brain cells. Researchers believe the compound works through a specific glutamate receptor (mGluR5) and decreases glutamate activity.

Researchers bred mice to have the hallmarks of autism -- including unusual social interactions, impaired communication and repetitive self-grooming -- and injected them with GRN-529.

Almost immediately, the mice showed fewer repetitive behaviors and more normal social interactions, although their communication was still not typical.

"These findings offer encouragement that research focused on developing medicines for core symptoms of autism are gaining momentum," said study co-author Robert Ring, vice president for translational research for Autism Speaks, an autism research and advocacy organization.

Experts caution, however, that although studies in animals can be useful, the results of animal studies often don't hold up in humans.

The study is in the April 25 issue of the journal Science Translational Medicine.

Autism is a neurodevelopmental disorder characterized by problems with social interaction, verbal and nonverbal communication, and restricted interests and behaviors. An estimated one in 88 U.S. children has autism, according to the U.S. Centers for Disease Control and Prevention.

Until recently, experts believed that the core symptoms of neurodevelopmental disorders such as autism and Fragile X syndrome, a genetic disorder that shares many of the same symptoms as autism, couldn't be treated well with medications, because the underlying abnormalities were "har
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3 4

Related medicine news :

1. Experimental Drug Offers Hope for Cystic Fibrosis Patients
2. Experimental Vaccine Shields Monkeys Against Ebola
3. Experimental targeted therapy shows early promise against medulloblastomas
4. Experimental nonsteroidal treatment of asthma shows promise
5. Experimental obesity drug avoids brain effects that troubled predecessors
6. Experimental treatments for cocaine addiction may prevent relapse
7. Experimental TB Test Called Fast and Accurate
8. Experimental Drug Shows Promise for Bone Marrow Disorder
9. Experimental Leukemia Drug Proves a Slam Dunk
10. Experimental Test May Spot Prostate Cancer Earlier, More Accurately
11. Experimental Drug Aids Kids With Nervous System Tumor
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Experimental Drug Eases Autistic Behaviors in Mice
(Date:7/30/2014)... 2014 According to the Yeast Infection No ... comprehensive guide that will help candida sufferers get rid of ... This book uncovers to readers the truth about yeast infection ... this book, people will discover natural and safe remedies to ... itching, burning, and irritation of the vagina or vulva. ...
(Date:7/30/2014)... CA (PRWEB) July 30, 2014 The San ... J. Helbock A.P.C. are announcing that they are now offering ... negative effects of asbestos exposure. , “Symptoms of asbestos ... exposed to the toxin 30 plus years ago may just ... Founder of The Law Office of Melinda J. Helbock A.P.C. ...
(Date:7/29/2014)... New York, NY (PRWEB) July 30, 2014 ... profile European fertility centers have been added to the ... Positivity continues to develop out of joint efforts — ... Cyprus create an initiative to offer affordable, state-of-the-art, and ... fertility clinics begins with a comprehensive study by ...
(Date:7/29/2014)... July 29, 2014 1Heart Caregiver ... communities with focus on Brain Fitness Education brings ... Ventura. Brain Fitness Program Director Tee Barr delivered ... Memory Care unit and the Assisted Living section ... Life Enrichment Director Christy Rozsa and Aegis Life ...
(Date:7/29/2014)... say they have discovered a chemical alteration in a ... confirmed in larger studies, could give doctors a simple ... attempting suicide. , The discovery, described online in ... in a gene involved in the function of the ... in turning what might otherwise be an unremarkable reaction ...
Breaking Medicine News(10 mins):Health News:Yeast Infection No More Book Review Exposes Linda Allen's Guide for Treating Yeast Infection – Vkool.com 2Health News:Yeast Infection No More Book Review Exposes Linda Allen's Guide for Treating Yeast Infection – Vkool.com 3Health News:The Law Office of Melinda J. Helbock A.P.C. Offers Case Evaluations for Possible Asbestos Claims 2Health News:Top European Fertility Clinics Join VisitandCare.com 2Health News:Top European Fertility Clinics Join VisitandCare.com 3Health News:Top European Fertility Clinics Join VisitandCare.com 4Health News:1Heart Caregiver Services Conducts Brain Fitness Education and Brings Tee Barr to Aegis Ventura 2Health News:1Heart Caregiver Services Conducts Brain Fitness Education and Brings Tee Barr to Aegis Ventura 3Health News:1Heart Caregiver Services Conducts Brain Fitness Education and Brings Tee Barr to Aegis Ventura 4Health News:A blood test for suicide? 2Health News:A blood test for suicide? 3
... More than 25 children have died of suspected encephalitis and ... Muzaffarpur district for the past few days //. ... the spread of the killer disease. The children reported sudden ... bouts of unconsciousness and convulsion leading to their death. ...
... clinical symptoms like depression, anxiety, suicidal thoughts and other ... in their body image than others - a study ... ,Dr. Jennifer Dyl of Brown Medical School in ... conscious with their body shape and weight are likely ...
... Mayo Clinic, Rochester, Minnesota has revealed that obesity was ... for the Hepatitis C virus (HCV). ,Lead ... found that obese patients treated for the chronic hepatitis ... better results when underlying abnormalities caused by excessive fat ...
... Europe threatens the public health systems leading to fall ... in the fertility-related studies and clinics performing assisted conception, ... said Paul Devroey, the chairman of the European Society ... more fertility organizations and policies related to development of ...
... tried to analyze the many reasons why some teen girls ... IVF treatments //. In his reading, they are just going ... ridiculed. ,Laurence Shaw, the deputy medical director of ... opinion that, it is the internal program charted by nature ...
... bane in the health policy of Britain. Experts arguably explain ... //marked or hurting it becomes difficult to identify and to ... an epidemic one in six people at some point of ... to warrant medical treatment. ,Though this is a ...
Cached Medicine News:Health News:Depression Could Quickly Grow Into UK’s Biggest Proble 2
(Date:7/29/2014)...  Neurocrine Biosciences, Inc. (Nasdaq: NBIX ) ... quarter 2014 financial results after the Nasdaq market closes ... a live conference call and webcast to discuss its ... August 7, 2014 at 8:00 a.m. Eastern Time (5:00 ... live conference call by dialing 866-952-1907 (US) or 785-424-1826 ...
(Date:7/29/2014)... , July 29, 2014  Sysmex America, Inc., a ... systems technology, will feature an exhibit booth during the ... and Clinical Lab Expo in Chicago ... "We are extremely excited to exhibit at ... interact with our customers and continue the dialogue on ...
(Date:7/29/2014)... Apex Medical Corporation (Apex, TWSE: 4106), a leading ... announces that it is appealing the judgment of the Regional ... Germany that found the headgear of certain mask ... initiated invalidity challenges against various ResMed patents in major countries. ... and junk patents. ResMed filed the lawsuit ...
Breaking Medicine Technology:Neurocrine Biosciences Announces Conference Call And Webcast To Report Second Quarter 2014 Financial Results 2New Product Offerings Highlight Sysmex's Presence at 2014 AACC in Chicago 2New Product Offerings Highlight Sysmex's Presence at 2014 AACC in Chicago 3Apex Continues Fighting Against Patents to Free Up Competition 2
... and BASEL, Switzerland, Nov. 15, 2010 Dalton ... created to provide clients with geographically diversified, fully ... of active pharmaceutical ingredients. In order ... efficiency, pharmaceutical development companies have been seeking Chemistry ...
... Nov. 12, 2010 Nephros, Inc. (OTC Bulletin Board: ... and marketing filtration products for therapeutic applications, infection control, ... three months ended September 30, 2010. ... prior year period. Reduced loss from operations by ...
Cached Medicine Technology:Dalton and Lonza Announce Co-operation to Provide Contract Chemistry Services and Manufacturing 2Dalton and Lonza Announce Co-operation to Provide Contract Chemistry Services and Manufacturing 3Nephros Reports 2010 Third Quarter Financial Results 2Nephros Reports 2010 Third Quarter Financial Results 3Nephros Reports 2010 Third Quarter Financial Results 4Nephros Reports 2010 Third Quarter Financial Results 5Nephros Reports 2010 Third Quarter Financial Results 6
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: