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Experimental Chemo Combo for Colon Cancer Disappoints
Date:4/3/2012

ll continue to search for new drug combinations that are more effective than the present regimens."

Cetuximab still has a role in the treatment of certain patients with stage 4 cancer, Whelan said.

And another expert said that, even though the drug failed to help these patients, important lessons have still been learned.

"Although this is a negative study, there is a benefit to patient care," said Dr. David Bernstein, chief, division of gastroenterology at North Shore University Hospital in Manhasset, N.Y. "The increased toxicity [side effects] seen with the addition of cetuximab did not translate into increased survival, and therefore this drug can be removed from the treatment cocktail without sacrificing outcome, and by its removal, lessen patient adverse events on therapy."

More information

The U.S. National Cancer Institute has more about colon cancer treatment.

-- Robert Preidt

SOURCES: Richard Whelan, M.D., chief of colorectal surgery, St. Luke's-Roosevelt Hospital, New York City; David Bernstein, M.D., chief, division of gastroenterology, North Shore University Hospital, Manhasset, N.Y.; Journal of the American Medical Association, news release, April 3, 2012


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