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ExonHit Presents Therapeutic and Diagnostic Programs for Alzheimer's at ICAD 2008
Date:7/1/2008

PARIS and GAITHERSBURG, Maryland, July 2 /PRNewswire-FirstCall/ -- ExonHit Therapeutics (ALTERNEXT-NYSE EURONEXT : ALEHT ; ISIN : FR0004054427), a drug and diagnostic company, today announced its presence at the International Conference on Alzheimer's Disease (ICAD 2008) taking place in Chicago (Illinois), July 26 to 31.

On this occasion, ExonHit will reveal several posters and participate in an oral presentation, entitled "EHT 0202: A Neuroprotective And Procognitive Alpha-secretase Stimulator Targeted Towards Alzheimer Disease Therapy", lead by Matthew Pando, Ph.D., Executive Vice President - Therapeutics of ExonHit.

"We're particularly delighted to take part in this international conference and we're proud to present all of our therapeutic developments and diagnostic innovations to the major experts and researchers in the neurodegenerative diseases. Based on its unique technological platform of alternative splicing, ExonHit has been working for years on building an efficient Alzheimer's franchise. It focuses on the development of a new generation of blood diagnostic tests but also on the discovery of innovative therapeutic solutions in a area where ExonHit has to line up among the top leading companies", has declared Philippe Rousseau, Chairman of the Management Board and Chief Financial Officer of ExonHit.

On the basis of several unique proprietary technologies of analysis of transcripts with alternative splicing, ExonHit built indeed a solid portfolio of both therapeutic and diagnostic products.

Nowadays, ExonHit is mostly developing two fully proprietary programs in Alzheimer's disease. The first one, relative to the EHT 0202 compound, is in fact on phase II of clinical trials. Based on a new action mechanism EHT 0202 redirects the processing of APP (Amyloid Precursor Protein), which plays a pivotal role in the evolution of Alzheimer's disease, at the expense of the beta amyloid peptide (Aβ). EHT 0202 could represent a major
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SOURCE ExonHit Therapeutics SA
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