Navigation Links
Exjade(R) Benefits Chronically Transfused Patients by Significantly Reducing Toxic Iron That Can Damage Key Organs, According to Landmark Trial
Date:12/8/2008

-First prospective, multicenter study to show Exjade removes iron from the heart in beta-thalassemia patients with mild to severe cardiac iron overload

-In a subgroup analysis of 341 patients with myelodysplastic syndromes (MDS), Exjade significantly reduced levels of toxic iron

-These results are part of the largest prospective trial in iron chelation, which includes more than 1,700 patients with various transfusion-dependent anemias

EAST HANOVER, N.J., Dec. 8 /PRNewswire/ -- New data from the largest prospective trial in iron chelation demonstrate the efficacy and safety of Exjade(R) (deferasirox) in treating chronic transfusional iron overload, a potentially life-threatening condition for patients who have had multiple blood transfusions to treat underlying anemias, including beta-thalassemia and myelodysplastic syndromes (MDS).

Data from this landmark trial, known as EPIC, were presented today at the 50th American Society of Hematology (ASH) Annual Meeting and Exposition in San Francisco, California.

The EPIC cardiac substudy showed that Exjade removed iron from the heart in beta-thalassemia patients, based on a statistically significant improvement in T2* magnetic resonance imaging, a validated technique to assess cardiac iron content (P<0.0001). The one-year substudy included 114 beta-thalassemia patients with cardiac iron overload, the leading cause of death in these patients.

"These data clearly demonstrate that deferasirox significantly reduces cardiac iron in beta-thalassemia patients with iron overload, which is a critical goal of treatment for these patients," said Dudley Pennell, MD, Professor of Cardiology, Royal Brompton and Harefield NHS Trust and Imperial College, London. "Cardiac complications caused by the buildup of toxic iron in the heart can be life-threatening for people living with thalassemia."


'/>"/>
SOURCE Novartis Pharmaceuticals Corporation
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9

Related medicine news :

1. Once-Daily Exjade(R) Shown to Remove Toxic Iron From the Heart and Liver, According to Data Presented at ASH
2. Integrated Benefits Institute Helps Employers Make the Business Case for Health and Productivity Improvement
3. Pharmacy Benefits Academy Set for 2009
4. Clock Ticking for Millions of Federal Employees Hoping to Avoid Blue Cross/Blue Shield Benefits Cut
5. Integrated Benefits Institute Announces Availability of 2007 IBI Benchmarking Data for Employers to Evaluate Effectiveness of their Health and Productivity Programs
6. States View Limits on Retiree Health Benefits
7. Blue Cross/Blue Shield Christmas Gift to Federal Employees: Surprise, Were Cutting Your Benefits!; Patients, Doctors and Health Care Providers Outraged
8. Healthcare Partners Medical Group to Host Free Medicare Benefits Presentations
9. A Third of Medicare Clients Unfamiliar With Benefits
10. Landmark study defines benefits of early HIV testing and treatment for infected infants
11. Bariatric Surgery Before Pregnancy Benefits Moms, Babies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... New York, New York (PRWEB) January 22, 2015 ... ( http://www.vaginalmeshlawsuit2015.com/ ) in the U.S. District Court, Southern District ... against C.R. Bard, Inc. in that proceeding’s first bellwether trial. ... defense request for a new trial after finding that C.R. ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Thousand of ... Medical Care recalled its GranuFlo and NaturaLyte dialysis concentrates ... underway in U.S. District Court, District of Massachusetts, Bernstein ... 20th, the Court has remanded a case filed by ...
(Date:1/22/2015)... released a new blog post presenting the basic features of ... an accidental death and dismemberment rider for a car insurance ... benefits if the insured dies in an accident. Accidental death ... insurance. , AD&D is not expensive and can be ...
(Date:1/22/2015)... Jolla, Calif. (PRWEB) January 22, 2015 ... Assemblymembers Susan Bonilla (D-Concord) and Kristin Olsen (R-Modesto) ... for their leadership in advancing biotechnology, biomedical science, ... Bonilla and Olsen each received the “2014 Life ...
(Date:1/22/2015)... Four years since the release of their debut recording ... marriage of Avasa & Matthew Love – the duo are pleased ... release through White Swan Records on February 24, 2015. , THE ... path available to all of us to walk out of the ...
Breaking Medicine News(10 mins):Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 2Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 3Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 4Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 3Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 4Health News:Accidental Death and Dismemberment Insurance Can Be Purchased at Low Prices Online 2Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 2Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 3Health News:THE ROAD by Avasa & Matthew Love -- A New Album 2Health News:THE ROAD by Avasa & Matthew Love -- A New Album 3Health News:THE ROAD by Avasa & Matthew Love -- A New Album 4
... likely to face infection, bleeding, study finds , , THURSDAY, ... defibrillators (ICDs) who,ve had multiple, previous pocket procedures have ... according to a study that included the 12 largest ... Krahn, of the London Health Sciences Center in Ontario, ...
... to blame, Japanese study finds , , THURSDAY, Dec. 11 (HealthDay ... a new Japanese study finds. , Those living in multigenerational ... times more likely to be diagnosed with serious heart disease ... by researchers at Osaka University reported in the Dec. 11 ...
... Playing tennis at the age of 90, living well beyond the age ... Researchers have discovered the secret to the fountain of youth. And now, ... ... RATON, Fla. (Business Wire EON) December 11, 2008 -- Natural Health ...
... 11 The Susan G. Komen for the Cure(R),Advocacy Alliance ... the next Secretary of Health and Human Services and director ... Alliance noted that,Daschle has long been a leader on health ... years related to breast cancer. , ...
... call for Americans to "Tell Their Stories" , ... Obama has indicated that healthcare reform will be a top ... Obama,s offer to serve as health and human services secretary, ... is asking Americans to help with reform efforts by sharing ...
... Philadelphia, 11 December 2008 Heart failure (HF) clinics ... patients with heart failure, yet there have been no ... clinics. To address this gap, the Quality of ... (HFSA) has developed a consensus statement summarizing the rationale, ...
Cached Medicine News:Health News:Multiple ICD Replacements Can Predict Complications 2Health News:Crowded Households Raise Women's Heart Risk 2Health News:Crowded Households Raise Women's Heart Risk 3Health News: Anti-Aging Miracle Physicians Have Been Waiting for is Finally Here : Free Book Available From Natural Health News Report Reveals the Secret to Staying Young 2Health News:Susan G. Komen for the Cure(R) Advocacy Alliance Applauds Selection of Senator Tom Daschle for HHS Secretary, White House Health Reform Czar 2Health News:Hospice Community Encouraged to Respond to Daschle Request to Participate in Information Gathering about Healthcare Concerns 2Health News:New statement outlines essentials of heart failure clinics 2
(Date:1/23/2015)... Jan. 23, 2015  MedScope ( www.medscope.org ), the leading ... a 2015 Connected World magazine Connected World ... (mPERS), that can be used anywhere, anytime. The nomination ... In nominating MedScope, Landon Garner , ...
(Date:1/23/2015)... baseball,s all-time hits leader, is the new spokesperson for the ... has announced. "Pete,s a Hall of Famer in ... board with Myoflex," said Ducere Pharma Chief Executive Officer ... known across all generations. The passion and intensity that Pete ...
(Date:1/23/2015)... , Jan. 23, 2015  Lixte Biotechnology Holdings, Inc. (OTCQB: ... Phase I trial of Lixte,s lead compound, LB‑100, is being ... John S. Kovach , M.D., the founder and ... to be completed at a single site. Accrual of patients, ...
Breaking Medicine Technology:MedScope Nominated by RacoWireless for Prestigious 2015 Connected World Magazine Connected World Award 2Pete Rose bets on Myoflex to relieve aches and pains 2Lixte Biotechnology Holdings Announces Expansion Of Clinical Sites For Its Phase I Trial Of Its Lead Anti-Cancer Compound, LB-100 2Lixte Biotechnology Holdings Announces Expansion Of Clinical Sites For Its Phase I Trial Of Its Lead Anti-Cancer Compound, LB-100 3
... Careers, the leading online career service for postgraduate life ... for life science Master,s and PhD graduates October 5-6. ... with and interview alumni and degree candidates from more ... leaving their office. "We are excited about ...
... NATICK, Mass., May 10, 2011 Boston Scientific Corporation ... to the Asthma and Allergy Foundation of America (AAFA) ... of asthma management and treatment.  The Company,s support coincides ... According to AAFA, more than 20 million ...
Cached Medicine Technology:Online Career Service to Hold World's First Virtual Job Summit for Postgraduate Life Scientists 2Boston Scientific Supports Asthma Awareness Month With Donation to Asthma Foundation 2Boston Scientific Supports Asthma Awareness Month With Donation to Asthma Foundation 3Boston Scientific Supports Asthma Awareness Month With Donation to Asthma Foundation 4
The Optima III line of laparoscopic hand instruments provides a well-crafted set of instruments designed for strength and durability....
The Bair Hugger Model 505 provides safe, quiet and effective warming to patients around the world....
Bair Hugger temperature management units are the only forced-air warming systems that can be used with an integrated, cost-effective method of fluid warming...
Provides outstanding patient warming and safety throughout the hospital and is nearly half the size and one-third the weight of earlier units....
Medicine Products: