Navigation Links
Exercise-related changes in estrogen metabolism may lower breast cancer risk
Date:5/6/2013

PHILADELPHIA Changes in estrogen breakdown, or metabolism, may be one of the mechanisms by which aerobic exercise lowers a woman's breast cancer risk, according to data published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

"Observational studies suggest physical activity lowers breast cancer risk, but there are no clinical studies that explain the mechanism behind this," said Mindy S. Kurzer, Ph.D., professor in the Department of Food Science and Nutrition at the University of Minnesota in Saint Paul. "Ours is the first study to show that aerobic exercise influences the way our bodies break down estrogens to produce more of the 'good' metabolites that lower breast cancer risk."

Kurzer and her colleagues conducted the Women in Steady Exercise Research (WISER) clinical trial, which involved 391 sedentary, healthy, young, premenopausal women. They randomly assigned the women to two age-matched, body mass index-matched groups: a control group of 179 women and an intervention group of 212 women.

While women in the control group continued a sedentary lifestyle for the entire study period, women in the intervention group performed 30 minutes of moderate-to-vigorous aerobic exercise five times a week for 16 weeks. Aerobic exercises included the treadmill, stair stepper or elliptical machine. The researchers adjusted the workout intensity for each individual so that the maximal heart rate was uniform among all participants.

Eighty-six percent of participants from the control group and 78 percent from the intervention group completed the study.

The researchers collected 24-hour urine samples on three consecutive days prior to study initiation and on three consecutive days at the end of the study. Using a state-of-the-art technique called liquid chromatography/tandem mass spectroscopy, they measured the amount of three parent estrogens, E1, E2 and E3, and
'/>"/>

Contact: Jeremy Moore
jeremy.moore@aacr.org
215-446-7109
American Association for Cancer Research
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Survival More Likely With Exercise-Related Cardiac Arrest: Study
2. Weight gain linked with personality trait changes
3. May 16 Webinar Reviews the Data Sources Used for Calculating Out-of-Network Rates in ACOs, Exchanges
4. Case Studies, Best Practices of Companies Operating Private Exchanges to Be Reviewed in May 14 Webinar
5. San Luis Obispo health insurance expert Susan Polk updates locals on new changes coming with the Affordable Care Act, the landmark health care reform law
6. RidgeCrest Herbals Changes eCommerce Order Management Solution to Shopatron's Unique Allied Commerce Model
7. Study reveals dramatic changes in global attitudes toward domestic violence
8. Scientists Spot Cancer Metabolism Changes
9. Guideline Changes Have Aspergers Community on Edge
10. Brain Changes Seen in Relatives of People With Alzheimers
11. Changes to Psychiatrys Bible Could Widen Definition of ADHD
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... -- Researchers say they have used human embryonic stem ... sperm. While this had already been done using ... these types of cells -- called primordial germ cells ... according to the team at the University of Cambridge ... is one of the earliest events during early mammalian ...
(Date:12/24/2014)... Angeles, CA (PRWEB) December 24, 2014 ... wreak havoc on those who have an intolerance to ... to diarrhea, gas, bloating, migraine headaches, joint pain and ... gluten free diet plans that deliver safe and ... certain foods that trigger a gluten allergy reaction. These ...
(Date:12/24/2014)... (PRWEB) December 24, 2014 The ... is a professional and in-depth research report on ... introduces COC basic information, including its definition, classification, ... news analysis, etc. This report also presents product ... Production is separated by regions, technology and applications. ...
(Date:12/24/2014)... For nearly 20 years, June Cotner has ... and all of life's rites of passage. Here, she ... Ling, in Toasts: The Perfect Words to Celebrate ... Organized by category and containing many original toasts written ... this timely tome contains sayings famous and profound, suitable ...
(Date:12/24/2014)... (PRWEB) December 24, 2014 As 2014 ... reminds homeowners that before investing time and money into ... a licensed professional that specializes in tankless and eco-friendly ... to replace their water heater in 2015 to research ... decision. , Greenstar Home Services specializes in ...
Breaking Medicine News(10 mins):Health News:Diet Doc Adds Gluten Free Diet Plans to Their Stable of Specialized Weight Loss Programs 2Health News:Diet Doc Adds Gluten Free Diet Plans to Their Stable of Specialized Weight Loss Programs 3Health News:COC/ Cyclic Olefin Copolymer Market: Global 2015-2020 Forecasts & Research Report Now at DeepResearchReports.com 2Health News:COC/ Cyclic Olefin Copolymer Market: Global 2015-2020 Forecasts & Research Report Now at DeepResearchReports.com 3Health News:Greenstar Home Services Offers Tankless Water Heater Advice to Local Homeowners 2
... , EXTON, Pa., July 29 Kensey Nash Corporation (Nasdaq: ... results for its fourth quarter and fiscal year ended June 30, 2009 ... , , Joe Kaufmann, President and CEO, will be ... at 9:00 A.M. Eastern Time. , , ...
... American Association ... ... in Cancer Prevention Research , a journal of the American Association for Cancer Research, ... head and neck. Furthermore, African Americans had far less HPV infection than whites, which led ...
... , , , ARMONK, ... ) announced today that St. Elizabeth Healthcare is ... roll-out of electronic medical records to improve patient care and lower costs. ... ) , , Today, only 1.5 percent of U.S. hospital ...
... , COLUMBUS, Ohio, July 29 ... New Drug Application (ANDA) for Risperidone Oral Solution, 1mg/mL by ... in 30mL bottles for immediate shipment to wholesalers and pharmacies ... Solution, 1mg/mL are AA rated to RISPERDAL(R) (risperidone) oral solution. ...
... ... and share , ... Skokie, Ill. (Vocus) July 29, 2009 -- Tabyat Partners, LLC. ( www.tabyat.com ), a ... its Web-based communication portal iluvmydoc.com™ ( www.iluvmydoc.com ). The site offers interactive services to ...
... , BOSTON, July 29 Although acne ... extremely common in adult women. Studies show that acne affects more ... more than 25 percent of women between the ages of 40-49 ... to report having acne than men. While there is no cure ...
Cached Medicine News:Health News:Kensey Nash Corporation Announces its Fourth Quarter and Fiscal Year End 2009 Earnings Release Date and Teleconference 2Health News:HPV Infection May Be Linked to Poor Head and Neck Cancer Survival Rates in African Americans 2Health News:HPV Infection May Be Linked to Poor Head and Neck Cancer Survival Rates in African Americans 3Health News:HPV Infection May Be Linked to Poor Head and Neck Cancer Survival Rates in African Americans 4Health News:St. Elizabeth Healthcare Drives Kentucky's Largest Electronic Medical Records Initiative With IBM 2Health News:St. Elizabeth Healthcare Drives Kentucky's Largest Electronic Medical Records Initiative With IBM 3Health News:Roxane Laboratories, Inc. Announces the Launch of Risperidone Oral Solution 1mg/mL 2Health News:Tabyat Partners, LLC. Launches iluvmydoc.com™, to Better Connect Patients with Doctors 2Health News:Hormonal Therapies Offer Effective Solutions for Many Adult Women With Acne 2Health News:Hormonal Therapies Offer Effective Solutions for Many Adult Women With Acne 3Health News:Hormonal Therapies Offer Effective Solutions for Many Adult Women With Acne 4
(Date:12/24/2014)... Tianyin Pharmaceutical Co., Inc. (NYSE MKT: ... biopharmaceutical, modernized traditional Chinese medicine (mTCM), branded generics ... the Company achieved the Public Notice (Gong Shi) ... of TPI,s Qionglai Facility (QLF) from the China ... period is a significant procedure of GMP certification ...
(Date:12/24/2014)... RALEIGH, N.C. , Dec. 23, 2014 /PRNewswire/ ... (NASDAQ: ENDP ) (TSX: ENL), and BioDelivery ... today that they have submitted a New Drug Application ... Food and Drug Administration (FDA).  Buprenorphine HCl Buccal Film ... enough to require daily, around-the-clock, long-term opioid treatment and ...
(Date:12/22/2014)... MONMOUTH JUNCTION, N.J. , Dec. 22, 2014 ... immunotherapy company marketing its CytoSorb® blood purification technology ... cardiac surgery patients in 28 countries worldwide, today ... Di Russo , MD, FACS, as its Senior ... 2015. Dr. Di Russo ...
Breaking Medicine Technology:TPI QLF Achieved Public Notice Status of GMP Certification 2TPI QLF Achieved Public Notice Status of GMP Certification 3Endo Pharmaceuticals and BioDelivery Sciences Announce NDA Submission for Buprenorphine HCl Buccal Film for the Management of Moderate to Severe Chronic Pain 2Endo Pharmaceuticals and BioDelivery Sciences Announce NDA Submission for Buprenorphine HCl Buccal Film for the Management of Moderate to Severe Chronic Pain 3Endo Pharmaceuticals and BioDelivery Sciences Announce NDA Submission for Buprenorphine HCl Buccal Film for the Management of Moderate to Severe Chronic Pain 4Endo Pharmaceuticals and BioDelivery Sciences Announce NDA Submission for Buprenorphine HCl Buccal Film for the Management of Moderate to Severe Chronic Pain 5CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 2CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 3CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 4CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 5
... SHANGHAI, Oct. 24, 2011 /PRNewswire-Asia/ -- ShangPharma Corporation ... "Company"), a leading China-based pharmaceutical and biotechnology research ... has, through its main Chinese subsidiary, Shanghai ChemPartner ... River Laboratories International, Inc.,s ("Charles River") Shanghai research ...
... and HOPKINTON, Mass., Oct. 24, 2011 DxTerity ... (NASDAQ: CALP ) announced today that ... strategic collaboration that will allow researchers to perform DxTerity,s ... platform minimizing sample processing time without compromising data quality. ...
Cached Medicine Technology:ShangPharma Purchases Shanghai In-vivo Drug Research Facility from Charles River 2DxTerity and Caliper Life Sciences Partner to Deliver NEAT® Multiplex Assays on Caliper's LabChip® Dx Platform 2DxTerity and Caliper Life Sciences Partner to Deliver NEAT® Multiplex Assays on Caliper's LabChip® Dx Platform 3DxTerity and Caliper Life Sciences Partner to Deliver NEAT® Multiplex Assays on Caliper's LabChip® Dx Platform 4
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: