Navigation Links
Exercise may help prevent brain damage caused by Alzheimer's disease
Date:8/15/2011

New York, NY, August 15, 2011 Regular exercise could help prevent brain damage associated with neurodegenerative diseases like Alzheimer's, according to research published this month in Elsevier's journal Brain, Behavior, and Immunity.

"Exercise allows the brain to rapidly produce chemicals that prevent damaging inflammation", said Professor Jean Harry, who led the study at the National Institute of Environmental Health Sciences in the United States. "This could help us develop a therapeutic approach for early intervention in preventing damage to the brain."

Previous research has already demonstrated that exercise after brain injury can help the repair mechanisms. This new study shows that exercise before the onset of damage modifies the brain environment in such a way that the neurons are protected from severe insults. The study used an experimental model of brain damage, in which mice are exposed to a chemical that destroys the hippocampus, an area of the brain which controls learning and memory. Mice that were exercised regularly prior to exposure produced an immune messenger called interleukin-6 in the brain, which dampens the harmful inflammatory response to this damage, and prevents the loss of function that is usually observed.

Pharmacological therapies to downregulate inflammation and address cognitive decline in older adults, and those with Alzheimer's disease, have been less successful. This research helps understand how exercise could be used to affect the path of many human conditions, such as neurodevelopmental disorders and neurodegenerative diseases. In addition, as a chemical model of neuronal damage was used, it also raises the possibility that exercise could offer protection against the potentially harmful effects of environmental toxins.

"This elegant series of experiments reveals an alternative pathway by which voluntary physical exercise may protect hippocampal neurons", said Dr. Ruth Barrien
'/>"/>

Contact: Francesca Webb
f.webb@elsevier.com
44-186-584-3244
Elsevier
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Small amount of exercise could protect against memory loss in elderly, CU study suggests
2. Regular Exercise Helps Keep Leg Arteries Clear
3. Post-Heart Attack Exercise May Depend on Where You Live
4. Regular Exercise Boosts the Brain, Too
5. Heart attack survivors from poorer neighborhoods get less exercise
6. Even a Little Exercise Helps the Heart, Study Finds
7. More Evidence That Exercise May Keep The Brain Sharp
8. Rigorous Exercise May Boost Benefits of Weight-Loss Surgery
9. Effects of exercise on meal-related gut hormone signals
10. Older Adults Have to Exercise More to Maintain Muscle Size, Study Finds
11. Exercise associated with longer survival after brain cancer diagnosis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/20/2014)... IN (PRWEB) October 20, 2014 ... Start, a secure cloud solution that enables healthcare ... of the ultimate healthcare-specific customer relationship management (“CRM”) ... meet the unique needs of the healthcare industry, ... experience for providers and patients by combining healthcare ...
(Date:10/20/2014)... Diego, CA (PRWEB) October 20, 2014 AttorneyOne.com, ... all the latest information from the FDA on Sit ... on October 10 not to purchase or use Sit and ... Sit and Slim II is promoted as weight loss product ... Sibutramine, removed from the market in 2010 for safety reasons, ...
(Date:10/20/2014)... 2014 National Teen Driver Safety Week is ... Academy of Pediatrics (Ohio AAP, http://www.ohioaap.org ) is joining ... of teen drivers to talk to their teens and always ... vehicle crashes are the leading cause of death for U.S. ... fatal crashes, and 859 (42%) of those teen drivers were ...
(Date:10/20/2014)... Houston plastic surgeon Dr. Christopher Patronella ... innovative True Form Tummy Tuck® method as ... at The University of Texas Medical Branch in ... medical student. Patronella, who is a founding partner of ... in Texas, The Aesthetic Center for Plastic Surgery ...
(Date:10/19/2014)... (PRWEB) October 19, 2014 Dr. Babatunde ... Fund, welcomes news of a ceasefire agreement that is ... than 200 girls who were kidnapped from the north-eastern ... languished in captivity long enough, and it is high ... communities," stated Dr. Osotimehin. , "We owe it to ...
Breaking Medicine News(10 mins):Health News:Healthcare Relationship Management (HRM) Leader hc1.com® Launches hc1® Quick Start™ 2Health News:FDA Advises Not to Use Sit and Slim II: AttorneyOne Monitors and Keeps Consumers Informed 2Health News:Ohio AAP Promotes National Teen Driver Safety Week 2Health News:Plastic Surgeon Patronella Presents Artistically-Inspired Tummy Tuck Method to Future Generation of Plastic Surgeons in Texas 2
... N.C. , Jan. 19 Sodium consumption is a hot ... their recipes to find ways to have products that everyone can feel ... in sodium—40% to 70% less than table salt—and tastes good. , In ... salt. Total sales that year did not even reach $100.00 . ...
... , , ATLANTA , Jan. ... Director of the Unit of Interventional Radiology at the European ... Oncology 2010 Best Poster Award by Dr. Shaun Samuels ... Micro-Bland Embolization Combined with Radiofrequency Ablation for Treating Complex Hepatic ...
... Speaker Nancy Pelosi , House Majority Leader Steny ... availability this afternoon in the Capitol following a Democratic leadership meeting. Below ... , As you may be aware, we just had a meeting ... you,re aware of in Massachusetts and the rest, we,re still ...
... rationing health care, particularly at the end of life, may ... Johns Hopkins emeritus professor of neurology called for the start ... this month,s issue of the Journal of Medical Ethics ... Professor Emeritus of Pediatric Neurology and a faculty member of ...
... with spinal injuries, experts say , , TUESDAY, Jan. 19 ... were able to form proper brain connections in newborn mice, ... their study was the first to show that stem cells ... link correctly in the brain. The findings, they say, could ...
... The cholesterol drugs might reduce risk of infection, researchers find ... known as statins hold promise as a treatment for sickle ... , The findings, published Jan. 19 in the ... mice, so it,s not clear if humans with the disease ...
Cached Medicine News:Health News:Ocean's Flavor Natural Sea Salt is Helping Companies Reach Low Sodium Goals 2Health News:Ocean's Flavor Natural Sea Salt is Helping Companies Reach Low Sodium Goals 3Health News:Orsi Awarded First Place for Procedure with Embozene(TM) Microspheres 2Health News:Transcript of Pelosi, House Democratic Leaders' Press Availability Today Following Leadership Meeting 2Health News:Transcript of Pelosi, House Democratic Leaders' Press Availability Today Following Leadership Meeting 3Health News:Reasoning through the rationing of end-of-life care 2Health News:Stem Cells Become Functioning Neurons in Mice 2
(Date:10/20/2014)... , Oct. 20, 2014 Valeritas, Inc., ... designed for patients with Type 2 diabetes, announced today ... Chain Excellence Award. The award was presented October 16 ... Columbus, Ohio . ... judged across a variety of metrics specifically targeted at ...
(Date:10/20/2014)... , Oct. 20, 2014 Lpath, ... leader in bioactive lipid-targeted therapeutics, received official notification from ... been granted another key patent supporting its iSONEP™ ... issued patent, European patent No. 2087002, claims compositions ... in Lpath,s two lead compounds, iSONEP and ASONEP. ...
(Date:10/20/2014)... YORK and RALEIGH, N.C., Oct. 20, 2014 ... Hereditary Neuropathy Foundation (HNF), both philanthropies, announced today ... drug candidates for the treatment of the rare ... BioPontis Alliance announced its alliance model earlier ... a first demonstration of a collaborative model where ...
Breaking Medicine Technology:Valeritas Receives 2014 Cardinal Health Supply Chain Excellence Award 2Valeritas Receives 2014 Cardinal Health Supply Chain Excellence Award 3Lpath Granted Key European Patent Related to iSONEP and ASONEP Programs 2Lpath Granted Key European Patent Related to iSONEP and ASONEP Programs 3Lpath Granted Key European Patent Related to iSONEP and ASONEP Programs 4The Hereditary Neuropathy Foundation and BioPontis Alliance for Rare Disease Partner to Develop Treatments for Charcot-Marie-Tooth 2The Hereditary Neuropathy Foundation and BioPontis Alliance for Rare Disease Partner to Develop Treatments for Charcot-Marie-Tooth 3
... 5, 2012  Orexigen ® Therapeutics, Inc. (Nasdaq: ... presenting at the 30th Annual J.P. Morgan Healthcare Conference in ... at 9:00 a.m. PST (12:00 p.m. EST). To listen to ... visit the Investor Relations section of the Company,s Web site ...
... , Company expects to meet or exceed ... and earnings declines due to Zyprexa patent expiration. , ... , Company expects to keep 2012 operating expenses essentially flat ... be in the range of $3.10 - $3.20. , ...
Cached Medicine Technology:Lilly Comments on 2011 Financial Guidance and Announces 2012 Financial Guidance 2Lilly Comments on 2011 Financial Guidance and Announces 2012 Financial Guidance 3Lilly Comments on 2011 Financial Guidance and Announces 2012 Financial Guidance 4Lilly Comments on 2011 Financial Guidance and Announces 2012 Financial Guidance 5