Navigation Links
Exercise improves functional and psycological ability and reduces steroid need in rheumatoid arthritis
Date:6/11/2009

Copenhagen, Denmark, Thursday 11 June 2009: Undertaking a supervised exercise programme can have beneficial effects on functional status and physical function, reduce the need for daily corticosteroid and anti-inflammatory intake and improve levels of depression and anxiety in people with rheumatoid arthritis (RA), according to a new study presented today at EULAR 2009, the Annual Congress of the European League Against Rheumatism in Copenhagen, Denmark.

A three-month programme, comprising moderate aerobic and strengthening exercises, conducted for 50-60 minutes three times per week, proved not only to be safe and beneficial both physically and in terms of quality of life for patients, but was also associated with a stabilising effect in disease activity measured by DAS28*. During the Portuguese study's three month period, researchers observed the following:

  • A 33% improvement in the HAQ (Health Assessment Questionnaire) disability index measurement of physical functioning (assessing ability to undertake everyday activities such as dressing, eating and walking, and whether assistance from another person or disability aids is required) (p < 0.023)

  • An improvement in physical function, as outlined below:

    • 55% improvement in the 'sit and stand' test (p=0.018)
    • 10% improvement in the right-hand grip test (p=0.025) and 15% in the left-hand grip test (p=0.035)
    • 19% improvement in the walk time test (p=0.063)

  • 62% of patients reported a reduced need for daily corticosteroid intake, from a mean dosage of 5.3mg/day of prednisone to 3.1mg/day (p=0.038)

  • 32% of patients reported stopping concurrent NSAID (non-steroidal anti-inflammatory drug) treatment altogether following the exercise programme (p=0.083)

  • Mean LDL (low-density lipoprotein) cholesterol increased from 90mg/dl to 125mg/dl (p=0.018)

  • 40% improvement in the Depression Anxiety Stress Scales (DASS), a self-reported assessment of negative emotional states, with 28% in the depression and 48% in the anxiety component respectively (p=0.078)

Dr Miguel Sousa of Instituto Portugus de Rheumatology, Lisbon, Portugal, who led the study, said: "When joints are stiff and painful, proactively taking exercise might seem undesirable for people with RA. However, our study has demonstrated that regular and supervised moderate aerobic workouts and strengthening exercises may be extremely beneficial for both a patient's physical and mental health, with a corresponding effect on quality of life. The challenge for physicians is to provide suitable motivation and reassurance to their RA patients in order that they initiate and stick with such a programme."

The observational longitudinal study followed eight physically-inactive patients (7 female; mean age of 59 (46-71) years; mean disease duration of 16 (3-30) years) with relatively stable RA (stable medication taken for at least three months; mean dose of methotrexate 17.5mg/week) for three months.


'/>"/>

Contact: Rory Berrie
eularpressoffice@uk.cohnwolfe.com
44-078-943-86425
European League Against Rheumatism
Source:Eurekalert

Related medicine news :

1. Exercise and yoga improves quality of life in women with early-stage breast cancer
2. Studies Prove Exercise Can Heal the Body Mind and Soul
3. 1 in 3 Varsity Athletes Has Exercise-Induced Asthma
4. Using the Internet to Promote Exercise
5. Less than 3 percent of UK 11-year-olds take enough exercise
6. Study fuels debate over whether exercise and body size influence ovarian cancer risk
7. Creatine in addition to exercise enhances strength in older adults
8. American Council on Exercise Offers 10 Tips for Surviving the Holidays
9. Highlands Acquisition Corp. Announces Exercise of Over-Allotment Option
10. Exercise And Health: Use Your Heart Rate As a Guide
11. Nine of 10 Women Attempt Exercise Goals After Initial Failure, Survey Shows
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... ... On Friday, June 10, Van Mitchell, Secretary of the Maryland Department of Health and ... their exemplary accomplishments in worksite health promotion. , The Wellness at Work Awards took ... the BWI Marriott in Linthicum Heights. iHire was one of 42 businesses to receive ...
(Date:6/24/2016)... ... June 24, 2016 , ... June 19, 2016 is World Sickle ... chronic pain and the benefits of holistic treatments, Serenity Recovery Center of ... Sickle Cell Disease. , Sickle Cell Disease (SCD) is a disorder of the red ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Amanda Cheng, ... treatment. Dr. Cheng has extensive experience with all areas of orthodontics, including robotic ... osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It ...
(Date:6/24/2016)... ... 24, 2016 , ... EB Medicine presented its first-ever “Issue ... conference in Ponte Vedra Beach, FL. The awards honor the outstanding work of ... and Pediatric Emergency Medicine Practice. , “With this award, we recognize the ...
(Date:6/24/2016)... ... ... National recruitment firm Slone Partners is pleased to announce the placement of ... President of North American Capital Sales at HTG Molecular . , ... the commercialization of the HTG EdgeSeq system and associated reagents in North America. , ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 23, 2016  MedSource announced today that it ... software solution of choice.  This latest decision demonstrates ... to their clients by offering a state-of-the-art electronic ... establishes nowEDC as the EDC platform of choice ... clients.  "nowEDC has long been a preferred EDC ...
(Date:6/23/2016)... 2016 Research and Markets has ... by Type (Organic Chemical (Sugar, Petrochemical, Glycerin), Inorganic Chemical), ... Parenteral) - Global Forecast to 2021" report to ... The global pharmaceutical excipients market is projected to reach ... 6.1% in the forecast period 2016 to 2021. ...
(Date:6/23/2016)... Research and Markets has announced the ... 2016 - Forecast to 2022" report to their offering. ... up to date financial data derived from varied research sources ... with potential impact on the market during the next five ... comprises of sub markets, regional and country level analysis. The ...
Breaking Medicine Technology: