Navigation Links
Exercise benefits patients with type 2 diabetes

OAK BROOK, Ill. Moderate-intensity exercise reduces fat stored around the heart, in the liver and in the abdomen of people with type 2 diabetes mellitus, even in the absence of any changes in diet, according to a new study published online in the journal Radiology.

Type 2 diabetes occurs when the body does not produce enough insulin, a hormone that regulates the movement of sugar into the cells, or when the cells resist the effects of insulin. The disease can lead to a wide range of complications, including damage to the eyes and kidneys and hardening of the arteries.

Exercise is recommended for people with diabetes, but its effects on different fat deposits in the body are unclear, according to the study's senior author, Hildo J. Lamb, M.D., Ph.D., from the Department of Radiology at Leiden University Medical Center in the Netherlands.

"Based on previous studies, we noticed that different fat deposits in the body show a differential response to dietary or medical intervention," he said. "Metabolic and other effects of exercise are hard to investigate, because usually an exercise program is accompanied by changes in lifestyle and diet."

For the new study, Dr. Lamb and colleagues assessed the effects of exercise on organ-specific fat accumulation and cardiac function in type 2 diabetes patients, independent of any other lifestyle or dietary changes. The 12 patients, average age 46 years, underwent MRI examinations before and after six months of moderate-intensity exercise totaling between 3.5 and six hours per week and featuring two endurance and two resistance training sessions. The exercise cycle culminated with a 12-day trekking expedition.

MRI results showed that, although cardiac function was not affected, the exercise program led to a significant decrease in fat volume in the abdomen, liver and around the heart, all of which have been previously shown to be associated with increased cardiovascular risk.

"In the present study we observed that the second layer of fat around the heart, the peracardial fat, behaved similarly in response to exercise training as intra-abdominal, or visceral fat," Dr. Lamb said. "The fat content in the liver also decreased substantially after exercise."

Dr. Lamb noted that the exercise-induced fat reductions in the liver are of particular importance to people with type 2 diabetes, many of whom are overweight or obese.

"The liver plays a central role in regulating total body fat distribution," he said. "Therefore, reduction of liver fat content and visceral fat volume by physical exercise are very important to reverse the adverse effects of lipid accumulation elsewhere, such as the heart and arterial vessel wall."

The findings point to an important role for imaging in identifying appropriate treatment for patients with type 2 diabetes, which the World Health Organization projects to be the seventh leading cause of death worldwide by 2030.

"In the future, we hope to be able to use advanced imaging techniques to predict in individual patients which therapeutic strategy is most effective: diet, medication, exercise, surgery or certain combinations," Dr. Lamb said.


Contact: Linda Brooks
Radiological Society of North America

Related medicine news :

1. Study: Women not getting enough exercise; at risk of developing metabolic syndrome
2. Exercise and attitude may be thermostat for hot flashes
3. Women Less Apt Than Men to Get Recommended Daily Exercise
4. Exercise improves quality of life during breast cancer treatment
5. Swallowing exercises linked with short-term improvement among patients with head and neck cancer
6. Swallowing exercises can help patients with head and neck cancer
7. Exercise May Help Patients With High Blood Pressure Live Longer
8. Exercise helps smokers to quit smoking, to remain smoke-free and to reduce the risk of death
9. A comparison of 2 home exercises to treat vertigo
10. Guidelines say diet, exercise, weight control improve odds after cancer diagnosis
11. Exercise Twice a Day Vital for Your Dogs Health, Expert Says
Post Your Comments:
(Date:11/27/2015)... ... November 27, 2015 , ... According to an article ... Dental Association meeting in Washington D.C. revolved around the fact that proper dental care, ... The talk stressed the link between periodontal disease (more commonly referred to as gum ...
(Date:11/27/2015)... ... November 27, 2015 , ... ... convenient way to dispense prescription medications at home, so he invented the patent-pending ... monitor and dispense prescription medications. In doing so, it could help to prevent ...
(Date:11/27/2015)... , ... November 27, 2015 , ... MPWH, the No.1 Herpes-only dating community in the ... Table 1-1 ). More than 3.7 billion people under the age of 50 ... (HSV-1), according to WHO's first global estimates of HSV-1 infection . , "The data ...
(Date:11/27/2015)... ... 2015 , ... Keeping in mind challenges faced by parents ... consultation, has collaborated with a leading web-based marketplace for extra-curricular activities for children ... and bring advice from parenting experts within their reach. As a part of ...
(Date:11/27/2015)... ... November 27, 2015 , ... Indosoft Inc., ... the incorporation of Asterisk 11 LTS (Long Term Support) into its Q-Suite 5.10 ... brings Q-Suite 5.10 up-to-date with a version of Asterisk that will receive not ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... -- Research and Markets ( ) has announced the ... to 2019 - Rise in Cardiac Disorders and Growing Awareness ... their offering. Boston scientific ... scientific and others. --> The market is ... Boston scientific and others. ...
(Date:11/26/2015)... , November 26, 2015 ... of the "2016 Future Horizons and ... Abuse Testing Market: Supplier Shares, Country Segment ... to their offering. --> ... "2016 Future Horizons and Growth Strategies ...
(Date:11/26/2015)... November 26, 2015 ... "Self Administration of High Viscosity Drugs" report ... has announced the addition of the "Self ... their offering. --> Research and Markets ... the "Self Administration of High Viscosity Drugs" ...
Breaking Medicine Technology: