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Exercise May Blunt Salt's Effect on Hypertension
Date:3/23/2011

By Alan Mozes
HealthDay Reporter

WEDNESDAY, March 23 (HealthDay News) -- Physical activity may diminish the negative impact of a high-salt diet on blood pressure, a new study suggests.

Researchers found that the more people exercise, the less their blood pressure will rise in response to a high-salt diet.

"For those with low physical activity, their blood pressure will increase more if they increase their sodium intake," said study co-author Dr. Jiang He, chair of the department of epidemiology at the Tulane University School of Public Health and Tropical Medicine in New Orleans.

"It's a little bit of a surprise," He added. "But this is the first study to look at this particular association between physical activity and salt sensitivity and blood pressure. But after thinking it over it makes sense, because we already know that physical activity will reduce blood pressure."

He and his colleagues are slated to present their findings Wednesday at the American Heart Association's meeting on nutrition, physical activity and cardiovascular disease, held in Atlanta.

High blood pressure, or hypertension, is a leading cause of stroke. Because of salt's association with high blood pressure, the American Heart Association recommends consuming less than 1,500 milligrams (mg) of sodium per day.

To explore a potential association between exercise and the hypertensive role of dietary salt, the authors focused on roughly 1,900 men and women (average age 38) living in a rural region in northern China. None took blood pressure medication during the study.

For one week all of the participants consumed 3,000 mg of sodium a day in their diet; for another week, they were placed on a high-sodium diet -- 18,000 mg per day.

Nine blood pressure readings were taken each week, and questionnaires were completed to assess routine levels of physical activity, ranging from "very active" to "quite sedentary."

When switching from the lower-sodium to a high-sodium diet, those who experienced a 5 percent or greater boost in their systolic blood pressure (the heart contraction measure represented by the top figure of a blood pressure reading) were deemed "high salt-sensitive."

Those reporting the most physical activity had a 38 percent lower risk of being highly salt-sensitive than the least active group. This group was the least likely to see a 5 percent or greater rise in their blood pressure in response to a high-salt diet.

Compared with the most sedentary group, those in the next-to-highest activity group had a 17 percent lower risk of salt-sensitivity, and those in the next-to-lowest activity group had a 10 percent lower risk.

The team concluded that engaging in physical activity has a "significant," independent and progressively healthful impact on the degree to which salt sensitivity relates to blood pressure.

The authors acknowledged that the study needs to be repeated. Also, experts note that research presented at meetings has not been subjected to the same type of rigorous scrutiny given to research published in peer-reviewed medical journals.

Still, "there's no reason to think these findings will not apply to a U.S. population. Stress factors for hypertension are the same for a Chinese and American population," said He.

"So the basic message here is, first we need to encourage the population to both lower their sodium intake and to increase their physical activity," He added. Those who can't increase their physical activity, perhaps because of age or disability, should still be encouraged to follow a low-sodium diet, "because sodium has a marked affect on blood pressure," He said.

Lona Sandon, a registered dietitian and assistant professor of clinical nutrition at the University of Texas Southwestern Medical Center at Dallas, said that the findings highlight some of the well-known benefits of regular exercise.

"Even if we don't understand the mechanism of how it works, we definitely do know that people who exercise regularly have healthier blood vessels," she noted. "The blood vessels are like a muscle. And if you engage in cardiovascular activity, they are more pliable and respond better to changes in blood volume and blood pressure."

Why this is so merits exploration, Sandon said. "One explanation might be that people who exercise more lose more salt through their sweat," she said. "Or it could be that activity sends a different kind of physiological message to the body to excrete sodium. Or it could be that it triggers a mechanism that tells the blood vessels to relax.

"To understand which it is will take further study," she added.

More information

For more on high blood pressure, visit the U.S. National Heart, Lung, and Blood Institute.

SOURCES: Jiang He, M.D., Ph.D., professor and chair, department of epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans; Lona Sandon, R.D., assistant professor of clinical nutrition, University of Texas Southwestern Medical Center at Dallas; American Heart Association, news release, March 23, 2011


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