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Exelixis Commences Public Offering of Common Stock
Date:9/10/2007

SOUTH SAN FRANCISCO, Calif., Sept. 10 /PRNewswire-FirstCall/ -- Exelixis, Inc. (Nasdaq: EXEL) announced today that it has agreed to sell 7,000,000 shares of its common stock pursuant to an effective automatic shelf registration statement. Exelixis will also grant the underwriter a 30-day option to purchase up to an additional 1,050,000 shares of common stock. All of the shares in the offering will be sold by Exelixis. Goldman, Sachs & Co. is acting as the sole underwriter for the offering. Closing of the offering is expected to occur on or about September 13, 2007, subject to customary closing conditions.

The offering is being made pursuant to an effective automatic shelf registration statement. The offering may be made only by means of a prospectus supplement and the accompanying prospectus, copies of which may be obtained by sending a request to: Goldman, Sachs & Co., Attn: Prospectus Department, 85 Broad Street, New York, New York 10004, Fax: 212-902-9316 or Email at prospectus-ny@ny.email.gs.com.

This press release shall not constitute an offer to sell, or the solicitation of an offer to buy, any of the securities, nor shall there be any sale of these securities, in any state in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state.

About Exelixis

Exelixis, Inc. is a development-stage biotechnology company dedicated to the discovery and development of novel small molecule therapeutics for the treatment of cancer and other serious diseases.

Safe Harbor Statement

This press release contains forward-looking statements. Words such as "expects," "in
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SOURCE Exelixis, Inc.
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