Navigation Links
Excess Weight Speeds Up Osteoarthritis
Date:7/14/2009

Rapid loss of knee cartilage directly linked to being overweight in study

TUESDAY, July 14 (HealthDay News) -- If fear of heart disease and diabetes isn't enough reason to slim down, here's another: Being overweight or obese can cause rapid deterioration of the cartilage in the knee, leading to osteoarthritis, researchers report.

Osteoarthritis usually progresses slowly, but some patients experience a more rapid progression. This is the first study to connect obesity with fast progression of the disease and cartilage loss.

The report is published in the August issue of Radiology.

The researchers recruited 336 patients from a major osteoarthritis study. All were overweight and at risk of osteoarthritis, but had minimal or no loss of cartilage in their knees, said the researchers, who were led by Dr. Frank W. Roemer, an adjunct associate professor at Boston University and co-director of the quantitative imaging center in the department of radiology at Boston University School of Medicine.

During 30 months of follow-up, 20.2 percent of the patients showed a slow loss of knee cartilage and 5.8 percent had rapid cartilage loss, the study found.

The main risk factors for cartilage loss were pre-existing cartilage damage, being overweight or obese, tears or other injury to the cartilage at the knee joint (meniscus), and severe lesions seen on an MRI. Other factors include inflammation of the membrane lining the joints and abnormal build-up of fluid in the joint, according to the report.

Being overweight was associated with rapid cartilage loss, Roemer's team found. In fact, for every one-unit increase in body mass index, the chances of rapid cartilage loss increased 11 percent.

The association between obesity and rapid cartilage loss remained even after taking into account age, gender and ethnic background.

"It is a disease without treatment at present other than symptomatic -- mostly pain therapy and surgical total joint replacement," Roemer said.

"We know that weight loss is probably the most important factor to slow disease progression," Roemer said. "Additional studies will have to show if other measures, such as vitamins or targeted treatment of bone marrow lesions, will help to slow progression," he said.

"Osteoarthritis is the most common musculoskeletal disorder with major health and socioeconomic impact in our aging society," added Roemer.

Dr. Sean Scully, a professor of orthopedics at the University of Miami Miller School of Medicine in Florida, agreed that the danger of developing osteoarthritis is another reason to control weight.

"Don't let yourself get heavy," Scully said. "This study shows a direct correlation -- people who are heavy are the ones that are getting worse," he said.

Keeping your weight down -- through diet and exercise or weight-loss surgery -- could prevent the need for knee-replacement surgery, he said.

More information

For more information on osteoarthritis, visit the U.S. National Library of Medicine.



SOURCES: Frank W. Roemer, M.D., adjunct associate professor, Boston University, co-director, quantitative imaging center, department of radiology, Boston University School of Medicine; Sean Scully, M.D., Ph.D., professor of orthopedics, University of Miami Miller School of Medicine, Fla.; August 2009, Radiology


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Man Discovers Cure for Excessive Sweating
2. Cephalon Announces the Availability of NUVIGIL for the Treatment of Excessive Sleepiness Associated with Treated Obstructive Sleep Apnea, Shift Work Disorder and Narcolepsy
3. U.S. Study Shows Significant Improvement for Patients Suffering from Excessive Sweating with Topical Antiperspirant
4. Study Finds That Patients With Excessive Sweating Condition Are More Likely to Develop Skin Infections
5. Study helps identify college drinkers who might continue excessive drinking as adults
6. LCA-Vision New Excimer Laser Strategy to Reduce Operating Expenses in Excess of $3 Million Annually
7. Lack of strategies to manage MRI wait lists a key reason for excessive wait times
8. Excess Weight Ups Risk of Death, No Matter Where It Collects
9. Excess Weight Seems to Boost Breast Cancer Risk
10. Excess Weight Gain During Pregnancy a Risk to Mother and Child
11. Excess Drinking Shrinks the Brain
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Excess Weight Speeds Up Osteoarthritis
(Date:2/12/2016)... ... February 12, 2016 , ... The ThedaCare ... San Francisco General Hospital on April 5-7. The series is a multi-day, multi-workshop ... habits. The workshops cover a broad range of topics, including coaching skills, the ...
(Date:2/12/2016)... ... , ... The Jones Agency, a family owned insurance company with offices serving ... charity drive with the Tarrant Area Food Bank in the hopes of alleviating hunger ... need, the Tarrant County Food Bank offers hope and security to the one in ...
(Date:2/12/2016)... , ... February 12, 2016 , ... Miami Dental Specialists ... to their Miami dental office. Beginning in January, Miami Dental Specialists will offer ... Dental Specialists are the first office to be chosen by the dental implant manufacturer, ...
(Date:2/12/2016)... ... February 12, 2016 , ... Atlantic Information Services, Inc. (AIS) ... PBMs,” an upcoming Feb. 24 webinar that will discuss ways health plans and ... such as the $1,000-per-pill hepatitis C treatment Sovaldi and high-cost PCSK9 inhibitors to ...
(Date:2/12/2016)... ... ... The Central Coast Autism Spectrum Center (CCASC) invites teens ages 11-18 to its annual Winter ... teens with and without special needs to gather in a safe and supportive environment. Volunteers ... will take place on Saturday, Feb. 13 from 7 to 9:30 p.m. at Elks Lodge, ...
Breaking Medicine News(10 mins):
(Date:2/12/2016)... --> ... Global Clinical Trials Review, H2, 2015 provides an ... trials landscape along with top level data related ... & E7), Trial Status, Trial Phase, Sponsor Type ... involved and enlists all trials (Trial title, Phase, ...
(Date:2/11/2016)... 11, 2016 Stem cells are primitive cells ... self-renewal and the capacity to differentiate into mature cell ... as the first mouse embryonic stem cells were derived ... 1995 that the first culturing of embryonic stem cells ... not produced until 2006 As a result of these ...
(Date:2/11/2016)... -- Kindred Biosciences, Inc. (NASDAQ: KIN ), a biopharmaceutical ... pets, today announced the submission to FDA of the ... (NADA) for Zimeta™ (dipyrone injection, KIND-012).  Positive topline results ... the control of pyrexia (fever) in horses were recently ... --> The Chemistry, Manufacturing, and Controls technical ...
Breaking Medicine Technology: