Navigation Links
Excess Weight Speeds Up Osteoarthritis
Date:7/14/2009

Rapid loss of knee cartilage directly linked to being overweight in study

TUESDAY, July 14 (HealthDay News) -- If fear of heart disease and diabetes isn't enough reason to slim down, here's another: Being overweight or obese can cause rapid deterioration of the cartilage in the knee, leading to osteoarthritis, researchers report.

Osteoarthritis usually progresses slowly, but some patients experience a more rapid progression. This is the first study to connect obesity with fast progression of the disease and cartilage loss.

The report is published in the August issue of Radiology.

The researchers recruited 336 patients from a major osteoarthritis study. All were overweight and at risk of osteoarthritis, but had minimal or no loss of cartilage in their knees, said the researchers, who were led by Dr. Frank W. Roemer, an adjunct associate professor at Boston University and co-director of the quantitative imaging center in the department of radiology at Boston University School of Medicine.

During 30 months of follow-up, 20.2 percent of the patients showed a slow loss of knee cartilage and 5.8 percent had rapid cartilage loss, the study found.

The main risk factors for cartilage loss were pre-existing cartilage damage, being overweight or obese, tears or other injury to the cartilage at the knee joint (meniscus), and severe lesions seen on an MRI. Other factors include inflammation of the membrane lining the joints and abnormal build-up of fluid in the joint, according to the report.

Being overweight was associated with rapid cartilage loss, Roemer's team found. In fact, for every one-unit increase in body mass index, the chances of rapid cartilage loss increased 11 percent.

The association between obesity and rapid cartilage loss remained even after taking into account age, gender and ethnic background.

"It is a disease without treatment at present other than symptomatic -- mostly pain therapy and surgical total joint replacement," Roemer said.

"We know that weight loss is probably the most important factor to slow disease progression," Roemer said. "Additional studies will have to show if other measures, such as vitamins or targeted treatment of bone marrow lesions, will help to slow progression," he said.

"Osteoarthritis is the most common musculoskeletal disorder with major health and socioeconomic impact in our aging society," added Roemer.

Dr. Sean Scully, a professor of orthopedics at the University of Miami Miller School of Medicine in Florida, agreed that the danger of developing osteoarthritis is another reason to control weight.

"Don't let yourself get heavy," Scully said. "This study shows a direct correlation -- people who are heavy are the ones that are getting worse," he said.

Keeping your weight down -- through diet and exercise or weight-loss surgery -- could prevent the need for knee-replacement surgery, he said.

More information

For more information on osteoarthritis, visit the U.S. National Library of Medicine.



SOURCES: Frank W. Roemer, M.D., adjunct associate professor, Boston University, co-director, quantitative imaging center, department of radiology, Boston University School of Medicine; Sean Scully, M.D., Ph.D., professor of orthopedics, University of Miami Miller School of Medicine, Fla.; August 2009, Radiology


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Man Discovers Cure for Excessive Sweating
2. Cephalon Announces the Availability of NUVIGIL for the Treatment of Excessive Sleepiness Associated with Treated Obstructive Sleep Apnea, Shift Work Disorder and Narcolepsy
3. U.S. Study Shows Significant Improvement for Patients Suffering from Excessive Sweating with Topical Antiperspirant
4. Study Finds That Patients With Excessive Sweating Condition Are More Likely to Develop Skin Infections
5. Study helps identify college drinkers who might continue excessive drinking as adults
6. LCA-Vision New Excimer Laser Strategy to Reduce Operating Expenses in Excess of $3 Million Annually
7. Lack of strategies to manage MRI wait lists a key reason for excessive wait times
8. Excess Weight Ups Risk of Death, No Matter Where It Collects
9. Excess Weight Seems to Boost Breast Cancer Risk
10. Excess Weight Gain During Pregnancy a Risk to Mother and Child
11. Excess Drinking Shrinks the Brain
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Excess Weight Speeds Up Osteoarthritis
(Date:2/27/2017)... ... ... not your typical author. She went from working as a movie extra on Bill Murray’s ... she isn’t swimming as a performing mermaid. , Her book isn’t typical either. In Carothers’ ... comedic look at the dysfunctions of God’s family, before Lucifer was sent to hell. ...
(Date:2/27/2017)... ... February 27, 2017 , ... POUGHKEEPSIE, N. Y. – Peer-reviewed ... that despite scientific studies, the Center for Disease Control ( CDC ) and Infectious ... Kenneth B. Liegner, M.D. has compiled into a single volume a compelling argument ...
(Date:2/27/2017)... Francisco, CA (PRWEB) , ... February 27, 2017 ... ... clinic serving San Francisco and environs, is proud to announce an upgrade to ... information on the upgraded Yelp page on topics as diverse as Platelet Rich ...
(Date:2/26/2017)... ... February 26, 2017 , ... This is an ... world’s first to be ISO/IEC 17025:2005 INAB accredited for Der p 1 (house ... is the globally recognised standard that sets out requirements for the technical competence ...
(Date:2/26/2017)... ... February 26, 2017 , ... ... and reporting for healthcare organizations. This comprehensive and customizable solution empowers StaffBridge ... StaffBridge technology improves staffing efficiency, maximizes resource allocation, collects critical reporting data, ...
Breaking Medicine News(10 mins):
(Date:2/27/2017)... 2017 A recent research report published by ... alone is expected to reach a value of $55.8 billion by ... with 28 states have legalized marijuana for medical uses. In 2016, ... , North Dakota , Ohio ... use the drug in medical applications such as chemotherapies and pain ...
(Date:2/27/2017)... , Feb 27, 2017 Period October – December 2016 ... Operating result amounted to SEK -16.4 (-6.4) million Result ... share (-0.22) before and after dilution Cash flow from operating ... ... SEK 0.4 (0.4) million Operating result amounted to SEK -39.5 ...
(Date:2/24/2017)... Research and Markets has announced the addition ... Industry Forecast to 2025" report to their offering. ... The Global Wireless Health ... over the next decade to reach approximately $330.5 billion by 2025. ... for all the given segments on global as well as regional ...
Breaking Medicine Technology: