Navigation Links
Excess Pounds Raise Women's Cancer Risk

Obesity linked to a range of tumor types, studies find

WEDNESDAY, Nov. 7 (HealthDay News) -- A study of more than 1 million British women finds that overweight or obesity is to blame for about 5 percent of all cancer cases.

That's about 6,000 out of the 120,000 cancers affecting British women each year.

The study, by researchers from the University of Oxford, found that overweight and obese women are at higher risk of developing and dying from cancer, including breast cancer in postmenopausal women, colon cancer in premenopausal women, and pancreatic and kidney cancer generally.

"Among middle-aged and older women in the U.K., around 5 percent of all new cancers each year are actually due to overweight or obesity," estimates lead researcher Gillian Reeves, a statistical epidemiologist at Oxford's Cancer Research UK Epidemiology Unit.

"It is important that women be aware that being overweight carries some excess risk of certain types of cancers," Reeves said. "This is something they need to take into consideration alongside what we know are very strong adverse effects of being overweight on diseases like diabetes and heart disease."

In the study, Reeves and colleagues looked at the relationship between body-mass index (BMI), and cancer in 1.2 million British women aged 50 to 64, who took part in the Million Women Study. In the U.K., about 23 percent of all women are obese and 34 percent are overweight, according to national statistics.

During 5.4 years of follow-up, the researchers found more than 45,000 new cancers and more than 17,200 deaths from cancer. Being overweight or obese was linked to an increased incidence for all cancers combined, according to the report in the Nov. 7 online edition of the British Medical Journal.

Being overweight or obese can significantly increase the risk of some cancers in women, Reeves' group found.

Specifically, obese and overweight women were twice as likely to develop endometrial cancer and cancer of the esophagus compared with normal weight women. In addition, overweight and obese women had a 53 percent greater risk of kidney cancer, a 50 percent greater risk of multiple myeloma and a 24 percent greater risk of pancreatic cancer compared with their normal weight counterparts.

Obesity's link to cancer risk appeared to be associated with menopause for certain tumor types. For example, postmenopausal overweight or obese women had a 40 percent increased risk of developing breast cancer, while premenopausal and overweight women had a 61 percent increased risk of developing colorectal cancer, the researchers found.

The rise in cancer risk for overweight and obese women mirrored findings reported last Wednesday by the American Institute for Cancer Research and the Britain-based World Cancer Research Fund.

In that review of 7,000 studies, researchers found a definite link between excess fat and cancers of the esophagus, pancreas, colon and rectum, endometrium and kidneys in all women, as well as breast cancer in postmenopausal women.

Reeves' team also found that, in general, overweight and obese women were more likely to die from cancer once they developed the illness compared to slimmer women. The obesity-linked increase in the rate of cancer death was similar to the increase in cancer risk, the researchers reported.

One expert said the findings highlight another reason to stay slim.

"This study adds to the considerable body of evidence that shows the relationship between overweight obesity and cancer risk," said Eugenia E. Calle, managing director of analytic epidemiology at the American Cancer Society and author of an accompanying journal editorial.

To reduce their risk of cancer, women need to stay lean, Calle said. "Women should not gain weight in adulthood and maintain a weight that puts you on the lean end of normal weight," she said. This is also a benefit in preventing heart disease, diabetes and other medical problems, and maintaining a good quality of life, she added.

In related news, a study in the Nov. 7 issue of the Journal of the American Medical Association found obesity to be associated with 11 percent of deaths from cancers that are already considered to be obesity-related. The trend was not seen for non-obesity-related cancers, however.

"We estimate about 5 percent of all cancer deaths are associated with obesity," said the lead author of that study, Katherine M. Flegal, of the U.S. National Center for Health Statistics. "That ranges from -0.2 to 7.9 percent, so there is not much of a difference between the two studies."

More information

For more on cancer in women, visit the U.S. National Cancer Institute.

SOURCES: Gillian Reeves, Ph.D., statistical epidemiologist, Cancer Research UK Epidemiology Unit, University of Oxford, Oxford, U.K.; Eugenia E. Calle, Ph.D., managing director, analytic epidemiology, American Cancer Society, Atlanta; Katherine M. Flegal, Ph.D., U.S. National Center for Health Statistics, Hyattsville, Md; Nov. 7, 2007, British Medical Journal; Nov. 7, 2007, Journal of the American Medical Association

Copyright©2007 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Excessive TV Spurs Attention Trouble in Kids
2. Excessive Multivitamin Use May Raise Risk for Prostate Cancer, from Harvard Mens Health Watch
3. New tool to assess excessive daytime sleepiness in adolescents published in JCSM
4. Study: Modafinil is effective in treating excessive sleepiness
5. Challenge Tops 848,000 lbs, Urges Oaklanders to Team Up to Fight Epidemic of Excess Weight
6. Vanda Pharmaceuticals VSF-173 Excessive Sleepiness Phase II Clinical Trial Suggests Wake-Promoting Properties
7. Landmark Report: Excess Body Fat Causes Cancer
8. A chocolate cookie a day puts 20 pounds on an energetically-balanced kid in 4 years
9. The Challenge: Make It A Million (Pounds Lost That Is)
10. After Dropping 162 Pounds, Jodi Davis Inspires Other Michigan Women to Get Moving and Lose Weight Through
11. VioQuest to Present Data on Oncology Compounds VQD-002 and Lenocta(TM) at AACR-NCI-EORTC International Meeting
Post Your Comments:
Related Image:
Excess Pounds Raise Women's Cancer Risk
(Date:11/27/2015)... MINNEAPOLIS, Minn. (PRWEB) , ... November 27, 2015 ... ... you start failing. Secura Consultants has prided itself for not only fulfilling the ... best income protection solutions at an affordable price and providing top-tier customer service. ...
(Date:11/27/2015)... CA (PRWEB) , ... November 27, 2015 , ... ... on Accreditation of Allied Health Education Programs (CAAHEP) awarded accreditation to its Diagnostic Medical ... of CAAHEP accredited colleges, as only one of twelve colleges and universities in the ...
(Date:11/27/2015)... ... ... Dr. Thomas Dunlap and Dr. Patrick Coleman , cardiologist ... Medicine at St., Joseph Health System’s Santa Rosa Memorial Hospital , co-hosted the ... ways and require time-critical intervention to avoid large area heart damage and progressive infections ...
(Date:11/27/2015)... (PRWEB) , ... November 27, 2015 , ... ... contact center software Q-Suite, announces the incorporation of Asterisk 11 LTS (Long Term ... fully supported Asterisk 11 LTS brings Q-Suite 5.10 up-to-date with a version of ...
(Date:11/26/2015)... ... , ... Inevitably when people think Thanksgiving, they also think Holiday sales and ... Friday and Cyber Monday massage chair sales to receive the best pricing ... to find the best massage chair deals, they can see all of the coupons ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... DUBLIN , November 26, 2015 ... has announced the addition of the  ... in the European Cell Surface Marker ... Emerging Opportunities"  report to their offering.  ... announced the addition of the  "2016 ...
(Date:11/25/2015)...  Amgen (NASDAQ: AMGN ) today announced the ... the United States (U.S.) Food and ... to Humira ® (adalimumab). Amgen believes this submission ... FDA and represents Amgen,s first BLA submission using the ... M.D., executive vice president of Research and Development at ...
(Date:11/25/2015)... 25, 2015 AAIPharma Services Corp./Cambridge Major ... at least $15.8  Million to expand its laboratories ... . The expansion will provide additional office ... growing demands of the pharmaceutical and biotechnology markets. ... will provide up to 40,000 square feet of ...
Breaking Medicine Technology: