Navigation Links
Evolutionary history of SARS supports bats as virus source
Date:2/19/2008

irus works, it doesnt interact well with human cells, so at present theres no clear explanation about how the virus shifted from bat to human hosts. There must be other SARS-CoV in other animals that served as intermediate hosts.

With the data at hand, we see how the virus used different hosts, moving from bat to human to civet, in that order. So the civets actually got SARS from humans. We see this evolutionary sequence of events, but other biochemical reports of the poor interaction of bat viruses and human cells suggest that there remains a missing link in the wild.

To arrive at these conclusions, Janies and colleagues secured genetic data of hundreds of different isolates of the SARS-CoV virus that had been found in humans, various bats, civets, raccoon badgers and pigs. Using the same equipment that was originally developed for the Human Genome Project, scientists determined the nucleotide sequence of each of the viruses. Bioinformatics came into play as the researchers linked many computers together to be able to analyze the massive amounts of data, comparing the viral genomes and building what is called a phylogenetic tree by searching for shared mutations. Phylogenetics is the study of the evolutionary relationships among various biological species, or in this case, viruses, believed to have a common ancestor.

The resulting tree is a branching diagram that illustrates the interrelationship of various viruses. The phylogenetic tree also shows the timeline of the travels and mutations of various strains of SARS as they jumped between host species. In this tree, the SARS-CoV virus traveled from bat hosts to humans, from humans to civets and pigs, and, in rare cases late in the outbreak, back to humans.

Janies lab took the analysis many steps further, using genomes from coronaviruses that are relatives of SARS-CoV that have been isolated in humans, cows, rats, cats, dogs, mice, turkeys and pigs. Adding these additional outgr
'/>"/>

Contact: Daniel Janies
Daniel.Janies@osumc.edu
614-292-1202
Ohio State University
Source:Eurekalert  

Page: 1 2 3 4

Related medicine news :

1. First Responders Acquire Revolutionary MyClyns(TM) Protective Spray
2. Evolutionary phenomenon in mice may explain human infertility
3. ILC Dover Launches Revolutionary ArmorFlex (R) Pharmaceutical Product Contact Film
4. 10th Anniversary of Revolutionary Teaching Approach that Offers the Severely Disabled the Gift of Self-Expression - Through Painting
5. Precedent Launches Revolutionary Individual Health Insurance Plans in Texas
6. Revolutionary HD Surgical Footage from North Shore-LIJ Surgeon to be Broadcast for the First Time on ABCs 20/20, National Geographic Channel
7. Keeping Kids Healthy and Fit: The New York Kids Club Launches a Revolutionary New Fitness Program
8. World-renowned bioengineers to record history of medical inventions
9. Abuse history affects pain regulation in women with irritable bowel syndrome
10. First reputable book on the history of the Paralympic Movement
11. Immigrants Less Likely to Report Family History of Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Evolutionary history of SARS supports bats as virus source
(Date:4/26/2015)... York, New York (PRWEB) April 26, 2015 ... on April 21, 2015 in the U.S. District ... federally-filed testosterone lawsuits ( http://www.testosteronelawsuithub.com/ ) have ... proceedings. According to court documents, matters addressed included ... seek dismissal of claims involving their products on ...
(Date:4/26/2015)... NV (PRWEB) April 26, 2015 From ... Trivedi and his wife, Trivedi Master™ Dahryn Trivedi, spent ... FDA approved research laboratories and institutions in the efforts ... drugs, medicine and nutraceutical supplements for human health care. ... 12 different research labs and institutions. All lab facilities ...
(Date:4/26/2015)... 2015 Forbes Living is scheduled ... one which is synonymous with clean beaches, sparkling office buildings, ... are major economic influencers in the city on the Pacific ... show are pleased to announce the show will be broadcast ... 3:00 PM PDT. Tune in to find out what the ...
(Date:4/25/2015)... Francisco, California (PRWEB) April 26, 2015 ... his search for original 1965 Rolling Stones Greensboro Coliseum concert ... and was part of the Stone's Second American Tour. ... by Globe Poster Company out of Baltimore, Maryland. This ... in the northeast and southern cites. Globe uses garish ...
(Date:4/25/2015)... (PRWEB) April 25, 2015 Carinsurancequotesinfo.com has ... find low cost auto insurance for flatbed ... heavy goods and sometimes other vehicles. They are mainly ... insurance. The newly released blog post explains that by ... for trucks, vans and other commercial vehicles. , It ...
Breaking Medicine News(10 mins):Health News:Court Overseeing Federal Testosterone Treatment Lawsuits Convenes April Case Management Conference 2Health News:Court Overseeing Federal Testosterone Treatment Lawsuits Convenes April Case Management Conference 3Health News:Court Overseeing Federal Testosterone Treatment Lawsuits Convenes April Case Management Conference 4Health News:Trivedi Science™ Has Started Scientific Research to Create More Effective Pharmaceuticals and Nutraceuticals 2Health News:Trivedi Science™ Has Started Scientific Research to Create More Effective Pharmaceuticals and Nutraceuticals 3Health News:Forbes Living TV Will Air in San Diego, California 2Health News:Auto Insurance Quotes for Flatbed Trucks Available Online! 2
... ... , ... ... WASHINGTON , March 22 The National Patient ...
... March 22 The House of Representatives, passage ... significant improvements and changes in long-term care in a generation. ... Reform Act of 1987, championed provisions in the bill that ... the safety of people receiving care in long-term care facilities ...
... pushing dessert? According to a new study in the ... less healthy when they are purchasing for others. In ... (University of Miami) discovered that consumers exert more self-control when ... were asked to make a sequence of four choices from ...
... new study published in the April issue of Radiology ... in the diagnosis and treatment of H1N1 influenza by predicting ... the emergency room is very stressful and physicians need information ... imaging in the Department of Radiology at Tel Aviv Sourasky ...
... failure who didn,t undergo angioplasty fared better with the ... The anti-clotting drug Plavix is of modest benefit in ... failure and heart attack who don,t undergo angioplasty, a ... open blocked arteries. , Danish researchers analyzed data from ...
... ... and sports mental trainer, Dan Vitchoff to help him prepare for the ISSF World Cup ... and other experts to help him "train smart". The result for Richmond was the US ... ...
Cached Medicine News:Health News:National Patient Advocate Foundation Praises Historic Passage of Health Insurance Reform 2Health News:National Patient Advocate Foundation Praises Historic Passage of Health Insurance Reform 3Health News:National Patient Advocate Foundation Praises Historic Passage of Health Insurance Reform 4Health News:National Patient Advocate Foundation Praises Historic Passage of Health Insurance Reform 5Health News:Health Care Reform Bill Will Also Improve Long-Term Care 2Health News:Health Care Reform Bill Will Also Improve Long-Term Care 3Health News:Chest X-rays can help predict which H1N1 patients are at greatest risk 2Health News:Plavix Can Help Cut Death Risk in Certain Heart Patients 2Health News:PA Hypnosis Center Uses 'Smart Training' Sports Psychology for Gold Medal Success 2Health News:PA Hypnosis Center Uses 'Smart Training' Sports Psychology for Gold Medal Success 3
(Date:4/24/2015)... , April 24, 2015 Today, humanity takes a ... the singularity, and fat-free cronuts: 1-800 CONTACTS announces their new ... in just two taps. Two taps. New contacts. ... The app also features LensGauge which helps keep ... when you need to reorder. "Since our inception, ...
(Date:4/24/2015)... WHIPPANY, N.J. , April 24, 2015  Bayer Corporation ... Thursday, April 23 at the Bayer HealthCare US headquarters.  This ... relocating to the Whippany campus, and ... and Dad do every day at work. Fortunately, ... the office.  As a company whose mission is "Science For ...
(Date:4/24/2015)... N.C. , April 24, 2015 ... are establishing employee groups around the world to ... round-the-clock business hours. While there are many areas ... leaders must examine which best practices are necessary ... excellence. According to research by ...
Breaking Medicine Technology:Attention: We live in the future. Order contact lenses from your wrist with the 1-800 CONTACTS app for Apple Watch 2Bayer Hosts "Take Your Child to Work Day" 2Bayer Hosts "Take Your Child to Work Day" 3Bayer Hosts "Take Your Child to Work Day" 4Work Around the Clock: Building Effective Global Capabilities 2
The PerkinElmer LS 45 Luminescence spectrometer offers versatility, reliability and ease-of-use for routine analyses in an affordable package....
Spectra 2000 Digital Spectrophotometer is designed for quantitative and qualitative analysis in visible range from 320 nm to 1020 nm....
... 400 Series Spectrophotometer ... approach to UV-VIS instrumentation. ... are incorporated into a ... in features and performance ...
... Quebec Colony Counter allows the user to quickly ... models allows for digital counting or manual counting. ... standard lens increasing magnification to 3.0X. The adjustable ... be raised or lowered. The lens also rotates ...
Medicine Products: