Navigation Links
Evolution in the antibody factory
Date:3/11/2013

optimal fit of their surface molecules. Once the immune cells with their "surface-key" are able to bind to the "antigen locks" more readily than the finished antibodies, they receive survival signals and their key-form asserts itself.

"This is the 'survival of the fittest' as previously described by Charles Darwin on a molecular level," compares Meyer-Hermann. Studies with mice were able to be confirmed in computer simulations only under the assumption that the B cells compete with their own products namely the antibodies for the right to bind to antigens.

This astounding mechanism could, in the future, improve conventional vaccination methods. "It is plausible that patients could be administered, in addition to a vaccine, sufficiently-strong-binding antibodies," explains Meyer-Hermann. "Our models constructed in the computer suggest that this method accelerates the process of identifying optimal antibodies." The scientists suspect that the addition of antibodies manipulates the reaction to vaccination, since the newly-generated antibodies are now in competition with the externally-introduced molecules. The conditions for selection are thus intensified and the B cells react by producing optimal antibodies earlier on. The result is that vaccinations could take effect quicker.


'/>"/>
Contact: Birgit Manno
Birgit.Manno@helmholtz-hzi.de
49-531-618-11411
Helmholtz Centre for Infection Research
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. New Clues to the Evolution of the Human Brain
2. Evolution May Explain Runners High, Study Says
3. Losing money, emotions and evolution
4. A Revolutionary Dietary Paradigm: New Cookbook Features A SOS-free (Salt, Oil, Sugar ) Diet That Delivers the Optimal Food Plan for Renewing Health
5. Vygone Presents a Revolutionary Electro Waveform Device to Help Treat Molluscum Contagiosum Lesions
6. Oxford University Press launches Evolution, Medicine, and Public Health
7. Evolutionary information improves discovery of mutations associated with diseases
8. New Queens spin-in company to revolutionize cancer detection
9. An open platform revolutionizes biomedical-image processing
10. Genes of Africas Khoe-San Peoples Give Clues to Human Evolution
11. Bird tree tells new tale of evolution
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Evolution in the antibody factory
(Date:4/21/2015)... April 21, 2015 The joint venture ... it is opening its first freestanding emergency room later ... Arizona and will be licensed under Dignity Health Arizona ... Health and Adeptus Health joint venture. , Tim Bricker, ... Mercy Gilbert Medical Centers said the new facility will ...
(Date:4/21/2015)... April 21, 2015 Wireless Analytics, ... has been recognized by the Boston Business Journal as ... ranking was announced at a recent event celebrating the ... of the fastest-growing private companies in Massachusetts. , Wireless ... the state that recorded the fastest revenue growth from ...
(Date:4/21/2015)... The report “Dermatitis – ... on the therapeutic development for Dermatitis. ... new targets and MOAs to produce first-in-class ... is available @ http://www.rnrmarketresearch.com/dermatitis-pipeline-review-h1-2015-market-report.html . ... involved in the therapeutic development for Dermatitis ...
(Date:4/21/2015)... Edward Avalos, USDA Under Secretary for Marketing ... of the California Department of Food and Agriculture, have ... GrowRIVERSIDE Conference: The Future of Local Food, conference organizers ... nationally known experts intensifies an already strong line-up of ... slated to speak at the June 11-13 event. ...
(Date:4/21/2015)... Wojo Nutrition announces Abe’s ... its healthiest, will carry Wojo Nutrition's lines of single ... Nutrition, they’ve launched a revolution in the vitamin industry ... meet their multifaceted goals. Their line of single serving ... has been specially formulated to be as unique as ...
Breaking Medicine News(10 mins):Health News:Dignity Health and Adeptus Health to Open First Freestanding Emergency Room in Chandler, Arizona 2Health News:Dignity Health and Adeptus Health to Open First Freestanding Emergency Room in Chandler, Arizona 3Health News:Wireless Analytics Ranked as 25th Fastest Growing Private Company in Massachusetts 2Health News:Dermatitis Therapeutic Development and Pipeline Market Review H1 2015 Available at RnRMarketResearch.com 2Health News:Dermatitis Therapeutic Development and Pipeline Market Review H1 2015 Available at RnRMarketResearch.com 3Health News:Dermatitis Therapeutic Development and Pipeline Market Review H1 2015 Available at RnRMarketResearch.com 4Health News:USDA Under Secretary, former CA Agriculture Director to Address 2nd Annual “GrowRIVERSIDE” Conference in June 2Health News:USDA Under Secretary, former CA Agriculture Director to Address 2nd Annual “GrowRIVERSIDE” Conference in June 3Health News:Wojo Nutrition Announces their Lines of Single Serving Liquid Vitamins will be Available for Purchase online at Abesmarket.com Beginning in May 2
... growing evidence that supports an association between atypical fractures of ... without trauma and the use of bisphosphonates, drugs proven ... osteoporosis. While the risk for suffering an atypical femur fracture ... in 1,000 patients after six years of treatment research ...
... HealthDay Reporter , MONDAY, Feb. 6 (HealthDay News) -- ... the first line of defense is lifestyle changes such as ... lifestyle changes don,t get blood sugar levels under control, the ... the first oral treatment that should be given. ...
... Institute at Jefferson joint researchers continue to seek better ... (PJI) in patients following total joint arthroplasty. Their ... in diagnosing urinary tract infections, can also have a ... study built on previous work conducted by Javad Parvizi, ...
... By Serena Gordon HealthDay Reporter , MONDAY, ... the pancreas has sweet-taste receptors -- like those found on ... is a common ingredient in many foods and beverages. Nutrition ... fructose and the new findings might bolster their concerns. ...
... , MONDAY, Feb. 6 (HealthDay News) -- ... linked to a slightly increased risk of death, a ... it should be taken into account by doctors and ... The investigators analyzed the findings of 10 clinical ...
... by Van Andel Research Institute (VARI) scientists enables the ... glioblastoma the most common and most aggressive malignant ... January in the Proceedings of the National Academy ... signaling activation and gene amplification for their susceptibility to ...
Cached Medicine News:Health News:Halting bone-building osteoporosis drug use cuts risk for additional atypical femur fracture in half 2Health News:Metformin Preferred Drug for Type 2 Diabetes, Experts Say 2Health News:Metformin Preferred Drug for Type 2 Diabetes, Experts Say 3Health News:Rothman Institute at Jefferson research suggests use of LE strips to diagnose PJI 2Health News:Pancreas May 'Taste' Fructose, Hinting at Links to Diabetes 2Health News:Pancreas May 'Taste' Fructose, Hinting at Links to Diabetes 3Health News:Certain Cancer Drugs May Have Fatal Side Effects: Analysis 2Health News:Discovery predicts patient sensitivity to important drug target in deadly brain cancer 2
(Date:4/21/2015)... , April 21, 2015  The New York City ... LLP this week commenced two wrongful death lawsuits, each ... thinner Xarelto.  In each case it is alleged that ... fits all" for patients, and without a disclosure that ... once it starts. Both of the firm,s ...
(Date:4/21/2015)... Calif., April 21, 2015 Amgen (NASDAQ: ... quarter of 2015. Key results include: , Total ... 2014 to $5,033 million, with 12 percent product sales ... ® (denosumab), EPOGEN ® (epoetin alfa), Sensipar ... changes in foreign exchange rates impacted total revenue and ...
(Date:4/21/2015)... 2015  Perrigo Company plc ("Perrigo") (NYSE: PRGO ... has unanimously rejected the unsolicited Proposal (the "Proposal") from ... 8, 2015, to acquire all of the outstanding shares ... review, advised by its financial and legal advisors, the ... Company and its future growth prospects and is not ...
Breaking Medicine Technology:Law Firm Starts Two Suits for Deaths of Users of Xarelto 2Amgen's First Quarter 2015 Revenues Increased 11 Percent To $5.0 Billion And Adjusted Earnings Per Share (EPS) Increased 33 Percent To $2.48 2Amgen's First Quarter 2015 Revenues Increased 11 Percent To $5.0 Billion And Adjusted Earnings Per Share (EPS) Increased 33 Percent To $2.48 3Amgen's First Quarter 2015 Revenues Increased 11 Percent To $5.0 Billion And Adjusted Earnings Per Share (EPS) Increased 33 Percent To $2.48 4Amgen's First Quarter 2015 Revenues Increased 11 Percent To $5.0 Billion And Adjusted Earnings Per Share (EPS) Increased 33 Percent To $2.48 5Amgen's First Quarter 2015 Revenues Increased 11 Percent To $5.0 Billion And Adjusted Earnings Per Share (EPS) Increased 33 Percent To $2.48 6Amgen's First Quarter 2015 Revenues Increased 11 Percent To $5.0 Billion And Adjusted Earnings Per Share (EPS) Increased 33 Percent To $2.48 7Amgen's First Quarter 2015 Revenues Increased 11 Percent To $5.0 Billion And Adjusted Earnings Per Share (EPS) Increased 33 Percent To $2.48 8Amgen's First Quarter 2015 Revenues Increased 11 Percent To $5.0 Billion And Adjusted Earnings Per Share (EPS) Increased 33 Percent To $2.48 9Amgen's First Quarter 2015 Revenues Increased 11 Percent To $5.0 Billion And Adjusted Earnings Per Share (EPS) Increased 33 Percent To $2.48 10Amgen's First Quarter 2015 Revenues Increased 11 Percent To $5.0 Billion And Adjusted Earnings Per Share (EPS) Increased 33 Percent To $2.48 11Amgen's First Quarter 2015 Revenues Increased 11 Percent To $5.0 Billion And Adjusted Earnings Per Share (EPS) Increased 33 Percent To $2.48 12Amgen's First Quarter 2015 Revenues Increased 11 Percent To $5.0 Billion And Adjusted Earnings Per Share (EPS) Increased 33 Percent To $2.48 13Amgen's First Quarter 2015 Revenues Increased 11 Percent To $5.0 Billion And Adjusted Earnings Per Share (EPS) Increased 33 Percent To $2.48 14Amgen's First Quarter 2015 Revenues Increased 11 Percent To $5.0 Billion And Adjusted Earnings Per Share (EPS) Increased 33 Percent To $2.48 15Amgen's First Quarter 2015 Revenues Increased 11 Percent To $5.0 Billion And Adjusted Earnings Per Share (EPS) Increased 33 Percent To $2.48 16Amgen's First Quarter 2015 Revenues Increased 11 Percent To $5.0 Billion And Adjusted Earnings Per Share (EPS) Increased 33 Percent To $2.48 17Amgen's First Quarter 2015 Revenues Increased 11 Percent To $5.0 Billion And Adjusted Earnings Per Share (EPS) Increased 33 Percent To $2.48 18Amgen's First Quarter 2015 Revenues Increased 11 Percent To $5.0 Billion And Adjusted Earnings Per Share (EPS) Increased 33 Percent To $2.48 19Perrigo Board Unanimously Rejects Unsolicited Proposal From Mylan 2Perrigo Board Unanimously Rejects Unsolicited Proposal From Mylan 3Perrigo Board Unanimously Rejects Unsolicited Proposal From Mylan 4Perrigo Board Unanimously Rejects Unsolicited Proposal From Mylan 5Perrigo Board Unanimously Rejects Unsolicited Proposal From Mylan 6Perrigo Board Unanimously Rejects Unsolicited Proposal From Mylan 7Perrigo Board Unanimously Rejects Unsolicited Proposal From Mylan 8Perrigo Board Unanimously Rejects Unsolicited Proposal From Mylan 9
... Young Innovations, Inc. (NASDAQ: YDNT ) today announced ... 2012.  Sales for the first quarter of 2012 ... in the first quarter of 2011. Income from operations increased 5.3% ... million in the first quarter of 2011. Net income increased 5.6% ...
... April 23, 2012  This week COPAN launched videos ... The new videos were created for the Centers ... to be used in a web based course ... for healthcare providers.  The educational videos show proper ...
Cached Medicine Technology:Young Innovations, Inc. Announces Record Sales and EPS for the Quarter Ended March 31, 2012 2Young Innovations, Inc. Announces Record Sales and EPS for the Quarter Ended March 31, 2012 3Young Innovations, Inc. Announces Record Sales and EPS for the Quarter Ended March 31, 2012 4COPAN Produces CDC/Joint Commission Educational Specimen Collection Videos 2
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: