Navigation Links
Even tiny breast tumors can be aggressive and may require maximum therapy
Date:12/17/2007

SAN ANTONIO Breast tumors that are 1 centimeter in size or smaller no more than 0.4 inch in length can still be very aggressive and may require more intensive therapy than is routinely offered today, say researchers at Mayo Clinic in Jacksonville, Fla.

The study, which is being presented at the San Antonio Breast Cancer Symposium, is one of the few that has looked at outcomes of women who have tiny tumors that have not spread to the lymph nodes. The findings suggest that outcome of two types of breast cancer those classified as HER2 positive (HER2+) and triple negative may not depend on size alone.

This is a small study and so we cant make treatment recommendations from it, but it appears that biology and not only size matters when it comes to selecting therapy for small, invasive tumors, says the studys lead researcher, Surabhi Amar, M.D., a fellow in Hematology/Oncology at Mayo Clinic in Jacksonville.

Currently, there are no definitive treatment guidelines for tumors less than 1 centimeter in size because clinical trials are usually conducted on women whose tumors are larger or are associated with lymph node involvement, Dr. Amar says. We just dont have extensive data on tumors this small, so treatment becomes a matter of physician discretion.

Researchers at all three Mayo sites Jacksonville; Scottsdale, Ariz.; and Rochester, Minn. participated in the study, which examined 401 women who were treated for breast cancer between 2001 and 2005 at the breast cancer clinics in Jacksonville and Scottsdale.

The vast majority (87 percent, or 350 women) had tumors that were classified as ER/PR positive and HER2 negative (in short, HER2 negative/ER/PR+). Twenty-seven women (6.7 percent) had tumors that were HER2+ and 24 patients (5.9 percent) were diagnosed with triple negative cancer that is, ER/PR negative and HER2 negative. These classifications refer to receptors present on the outside of the tumor cell that are
'/>"/>

Contact: Paul Scotti
scotti.paul@mayo.edu
904-953-2299
Mayo Clinic
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Survival differences by race most apparent in advanced stages of breast cancer
2. MRI finds breast cancer before it becomes dangerous
3. Pathway links inflammation, angiogenesis and breast cancer
4. Drop in breast cancer incidence linked to hormone use, not mammograms
5. Breast cancer prevention practices vary across Canada
6. Eating junk food whilst pregnant and breastfeeding may lead to obese offspring
7. Acrylamide Wont Raise Breast Cancer Risk
8. New link between estrogen and breast cancer
9. Hypnosis Eases Pain of Breast Cancer Surgery
10. Discovery suggests location of genes for breast density, a strong risk factor for breast cancer
11. Longaberger Expands Horizon of Hope Campaign to Build Support for American Cancer Societys Breast Cancer Initiatives
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... have asthma, you may have an asthma action plan with ... to changes and understand when symptoms are getting worse and ... doing well, yellow means your asthma has worsened and action ... guidelines are now available to help your allergist steer you ... from the red zone. , "Management of acute loss of ...
(Date:7/31/2014)... Leelanau Peninsula’s newest winery, Aurora Cellars , ... East Horn Road in Lake Leelanau. Joining the Northern Loop ... is the 25th winery along the trail. The winery will ... events, making its trail event debut during the Harvest Stompede ... David and Faye Mathia opened the boutique winery in the ...
(Date:7/31/2014)... 2014 0-6 Pack Abs has finally been ... therapist expert Dr. James Vegher. Together they have launched ... relieve digestive issues, tone core muscles, improve posture, eliminate achy ... core exercises used to re-train the body in order to ... 0-6 Pack Abs review, Shane Michaels, a fitness ...
(Date:7/31/2014)... July 31, 2014 Adventist Health ... the U.S. including Florida Hospital Tampa, Florida Hospital ... Florida Hospital North Pinellas, Florida Hospital Wesley Chapel, ... Sebring, Florida Hospital Heartland Medical Center Lake Placid ... Networks list of Most Wired Hospitals and Health ...
(Date:7/31/2014)... Cosmetic Town has introduced a secure ... Doctors will be able to verify their patients before ... which guarantees their authenticity. This will help prospective ... receive information that has been verified to come from ... Cosmetic Town to filter out fake patients who leave ...
Breaking Medicine News(10 mins):Health News:Aurora Cellars Joins the Leelanau Peninsula Wine Trail 2Health News:Zero To Six Pack Abs System Review Exposes Tyler Bramlett And Dr. James Veghers’ New Ab Training Program 2Health News:Zero To Six Pack Abs System Review Exposes Tyler Bramlett And Dr. James Veghers’ New Ab Training Program 3Health News:Florida Hospital West Florida Region is Among the Most Wired Hospitals and Health Systems in the United States 2Health News:Cosmetic Town Improves Patient Experience Through Secure Verification of Patients and Doctors 2
... Venture," a one-day workshop about the basics of technology ... takes to launch a startup venture. Presentations ... intellectual property issues and business plans. Participants include Erica ... at Carnegie Mellon whose research focuses on the role ...
... 16, 2010Announcing the launch of the Liebert Mobile ... latest news, resources, press releases, research, and multimedia ... information across the biomedical, biotechnology, medicine, surgery, and ... is available with this free application. ...
... The ... ... its new Prodigy Count-a-dose™ April 1, a precise and safe syringe-filling device for the blind ... can easily measure and mix two insulins at one time. The device had been pulled ...
... A ... released today. This new concept protects consumers by enabling them to pay less, get more, and ... and legal problems relating to the construction. , ... (PRWEB) March 16, 2010 -- Stop Ripping Me Off! is the title of ...
... puts cost per life-year gained at about $66,200 ... agents for metastatic colon cancer improve patient survival but ... Emory University in Atlanta analyzed data from 4,665 patients, ... between 1995 and 2005. Compared to those who received ...
... bothered by treatment,s effects, study finds , TUESDAY, March ... enough radiation to shield patients from prostate cancer,s return ... as tricky as once thought, new research shows. , ... time. In fact, 10 years after treatment, prostate cancer ...
Cached Medicine News:Health News:Prodigy Re-Launches Syringe-Filling System for Blind and Low-Vision Diabetics 2Health News:Stop Ripping Me Off! Is the Title of a New Consumer Protection Book Being Released Today 2Health News:Stop Ripping Me Off! Is the Title of a New Consumer Protection Book Being Released Today 3Health News:Are New Chemo Treatments Cost-Effective? 2Health News:Prostate Cancer Radiation Side Effects May Subside With Time 2
(Date:7/31/2014)... 31, 2014 Vermillion, Inc. (NASDAQ: VRML), a multivariate ... hold a conference call on Thursday, August 14, 2014, at ... quarter ended June 30, 2014. Financial results will be issued ... Vermillion,s Chairman, President and CEO James LaFrance will ... Date: Thursday, August 14, 2014 Time: 4:30 p.m. ...
(Date:7/31/2014)... YORK , July 31, 2014 TB ... better, faster and affordable treatments for tuberculosis (TB), announced ... Vice President, Market Access. Ms. Robertson joins the organization ... company,s business in Sub-Saharan Africa and Eastern ... oversee the TB Alliance,s efforts to ensure beneficial new ...
(Date:7/31/2014)... NEW YORK , July 31, 2014 ... the eighth annual Prix Galien USA ... biomedical industry,s highest accolade and recognizes the technical, scientific ... and devices. This year brings the highest ... Galien USA . Nominees include biomedical ...
Breaking Medicine Technology:Vermillion Sets Second Quarter 2014 Conference Call for Thursday, August 14, 2014 2TB Alliance Names Elana Robertson Senior Vice President, Market Access 2TB Alliance Names Elana Robertson Senior Vice President, Market Access 3The Galien Foundation Announces 2014 Prix Galien USA Nominees for "Best Biotechnology Product," "Best Pharmaceutical Agent," and "Best Medical Technology" 2The Galien Foundation Announces 2014 Prix Galien USA Nominees for "Best Biotechnology Product," "Best Pharmaceutical Agent," and "Best Medical Technology" 3The Galien Foundation Announces 2014 Prix Galien USA Nominees for "Best Biotechnology Product," "Best Pharmaceutical Agent," and "Best Medical Technology" 4The Galien Foundation Announces 2014 Prix Galien USA Nominees for "Best Biotechnology Product," "Best Pharmaceutical Agent," and "Best Medical Technology" 5
... ... C Clarification of Oncogenic Pathways ... Potential Benefit in Liver Transplantation, MILAN, April 26 , - Systems Biology ... Meeting of the European,Association for the Study of the Liver (EASL), experts reported advances ...
... YORK, April 24 PulmoBioTech Inc. (OTC,Bulletin Board: PLMO) ... the areas that it will be investigating as part ... are:, 1. Efficacy Binding Studies 2. ... 4. Pyrogenicity 5. Immunological Testing 6. ...
Cached Medicine Technology:Basic Science Discoveries Yield Progress in Hepatology 2Basic Science Discoveries Yield Progress in Hepatology 3Basic Science Discoveries Yield Progress in Hepatology 4PulmoBioTech Announces Details of Its Regulatory Approval Experiments 2PulmoBioTech Announces Details of Its Regulatory Approval Experiments 3
The license agreement for the manufacturing and distribution of Bulgari eyewear was signed by Luxottica Group in 1997.,Bulgari eyewear is designed for sleek, select people who want to distinguish the...
... agreement between Brook Brothers and Luxottica ... by lightweight materials and a slender ... the unique features of the style ... with classic style and affordable to ...
... Ray-Ban brand debuted in 1937 with the ... was added to Luxottica Group's brand portfolio ... show business celebrities since day one, Ray-Bans ... far the best-selling sunglasses in the world. ...
... Group has been manufacturing the Anne Klein ... Klein eyewear collections are designed for an ... wear Anne Klein eyewear identifies herself with ... refined career woman who is image-conscious and ...
Medicine Products: