Navigation Links
Even Mismatched Cord Blood Can Help Kids
Date:2/13/2009

More patients, especially ethnic and racial minorities, could get transplants, study finds,,

FRIDAY, Feb. 13 (HealthDay News) -- An umbilical cord blood transplant from an unrelated or unmatched donor can still help children with deadly conditions such as cancer and sickle cell anemia, Duke University Medical Center researchers report.

They noted that unrelated cord blood may be easier to obtain than adult bone marrow, which means more patients would be able to receive treatment.

"Our study found that using cord blood can be effective, without increased complications, and can provide more matches for patients, including ethnic minorities," lead investigator Dr. Vinod Prasad, a pediatric oncologist in the Duke Pediatric Blood and Marrow Transplantation Program, said in a university news release. "Based on the findings of our study, we believe that unrelated cord blood transplant should be considered as an option for many of our young patients in need of a transplant."

Prasad and colleagues analyzed data on 314 patients treated at Duke between 1993 and 2007. The patients, ages 6 months to 21 years, had malignant and non-malignant conditions.

"In order to match a donor to a recipient, doctors compare HLA typing, a test usually performed on a blood sample," Prasad explained. "In every individual, HLA typing includes the specific genetic make-up at three locations -- within those locations, you are looking at one set from the mother and one from the father, so it ends up to be a six-point comparison."

"In this analysis of children whose donor units were matched at four of six points, the transplant was successful in many patients, with low incidence of complications. Results were similar to those seen in patients receiving closer matched transplants. Thus the use of the 4/6 matched donors improved access to transplant for patients, especially those of ethnic and racial minorities," Prasad said.

The study was expected to be presented Friday at an American Society of Bone Marrow Transplantation meeting in Tampa, Fla.

"We have done a terrific job in this country of increasing the number of volunteer donors listed in the National Marrow Donor Program registry over the past several years," Prasad said. "But the fact remains that, for many patients, finding a matched donor can be difficult. Ethnic and racial minorities have the hardest time finding a fully matched donor."

More information

The National Marrow Donor Program has more about cord blood transplants.



-- Robert Preidt



SOURCE: Duke University Medical Center, news release, Feb. 13, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Mismatched prostate cancer treatment more common than expected
2. Many prostate cancer patients receive improper or mismatched therapies
3. Specific antagonism lowers blood pressure
4. Restricting Blood Flow May Help Heart Bypass Patients
5. FDA Updates Prescription Guidelines for Blood Thinner
6. Doctors Often Miss High Blood Pressure in Kids
7. Back to School Means Return of School Blood Drives
8. Blood-flow detector software show promise in preventing brain damage
9. FDA Approves New Roche West Nile Virus Blood Screening Test
10. Australian-led international study shows blood pressure drugs cut death rate in type 2 diabetes
11. Laser blasts viruses in blood
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Even Mismatched Cord Blood Can Help Kids
(Date:2/9/2016)... ... February 09, 2016 , ... ... production of its newest mobility device, the StandUp Walker. Made entirely in the ... in the last 50 years. , StandUp Walker’s novel patent-pending design offers 2-in-1 ...
(Date:2/9/2016)... ... February 09, 2016 , ... BioPlus ... the continuation of the ‘Pay It Forward’ program into 2016. BioPlus partners with ... our specialty pharmacy. , “Since our Pay It Forward program began, we ...
(Date:2/9/2016)... ... 09, 2016 , ... The Bon-Ton Stores, Inc. (NASDAQ: BONT), ... announced it has raised $176,000 to benefit the Breast Cancer Research Foundation, Froedtert ... the University of Iowa, The Lynn Sage Cancer Research Foundation, and Masonic Cancer ...
(Date:2/9/2016)... ... February 09, 2016 , ... IsoComforter, Inc., one of ... the newly designed, innovative shoulder wrap. The newly designed shoulder wrap has ... injured arm and shoulder to promote faster healing. It is highly recommended for ...
(Date:2/9/2016)... ... , ... i2i Systems, an early innovator and developer of population health management ... KLAS report, Population Health Management 2015: How Far Can Your Vendor Take You? ... (PHM). The latest KLAS Report, leveraging over 200 user interviews, shines a light ...
Breaking Medicine News(10 mins):
(Date:2/9/2016)... Calif. , Feb. 9, 2016 /PRNewswire/ - Nevro ... company that is providing innovative evidence-based solutions for the ... release financial results for the fourth quarter and full ... 29, 2016. Company management will host a conference call ... Time) on Monday, February 29, 2016. www.nevro.com ...
(Date:2/9/2016)... ("Unilife" or "Company") (NASDAQ: UNIS ; ASX: UNS), a ... financial results for the second quarter of fiscal 2016 (three months ... Financial Results for the Second Quarter of Fiscal ... Revenue for the second quarter of fiscal 2016 was $4.5 million, ... receipts from customers for the second quarter of fiscal 2016 were ...
(Date:2/9/2016)... February 9, 2016 QGEN ... collaboration with 10x Genomics to develop and promote ... and bioinformatics. --> QGEN ; Frankfurt ... 10x Genomics to develop and promote comprehensive solutions ... --> QIAGEN N.V. (NASDAQ: QGEN ...
Breaking Medicine Technology: