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EuroPCR 2014 examines vascular response and long-term safety of bioresorbable scaffolds
Date:5/22/2014

s very interesting, but the bar that has been set by drug-eluting stents is very high and bioresorbable vascular scaffolds will need to match this, especially with regard to strut thickness and deliverability, said Prof Chaim Lotan, Head of the Cardiovascular Insitute, Hadassah University Hospital, Jerusalem, Israel.

Lotan also commented on the lack of long-term safety data being available. We need follow-up data of more than five years duration, possibly up to 10 years, because our previous experience with bare metal stents and drug-eluting stents has shown that we still see changes up to seven years. So we await long-term data for bioresorbable vascular scaffolds with regard to device behaviour and degradation patterns. We have seen cases where the stent has not yet degraded after three years and this could pose a problem for patients. Will the degradation occur as planned? Will the struts be apposed? Will we see late events such as thrombosis? All these are unanswered questions, he said.

Robert-Jan van Geuns, University of Rotterdam, The Netherlands, pointed to the potential advantages of using bioresorbable vascular scaffolds. In general, the data emerging are in line with the theory behind these devices: that vascular restoration therapy is going to heal vessels better than metallic stents. The long-term data has been demonstrated in non-complex patients, and we see that these patients do very well. We still need more data in more complex patients; there are now some non-randomised data available that are out to six-months, but we have to wait for the evidence in more complex patients before we can advocate the use of these devices in such patients, he said.


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Contact: Isabelle Uzielli
iuzielli@europcr.com
EuroPCR
Source:Eurekalert

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