Navigation Links
Ethicon Endo-Surgery Holds Metabolic Surgery Scientific Forum Featuring Research By Top Scientists
Date:7/28/2009

CINCINNATI, July 28 /PRNewswire/ -- Ethicon Endo-Surgery held a scientific symposium at the 26th Annual Meeting of the American Society for Metabolic & Bariatric Surgery (ASMBS) where four leading researchers shared innovative thinking coupled with mounting data about how the biochemical and endocrine effects of metabolic surgery is shaping research, treatment and health care policy for patients battling the co-morbid conditions associated with obesity, particularly Type 2 diabetes.

Moderating the discussion about the biology, mechanisms, and science behind metabolic surgery was Philip Schauer*, MD, Director of the Cleveland Clinic Bariatric and Metabolic Institute. Other participants included:

  • Randy J. Seeley*, Ph.D., Professor of Psychiatry and Associate Director of the Metabolic Disease Institute at the University of Cincinnati College of Medicine
  • Francesco Rubino*, MD, Chief of Gastrointestinal Metabolic Surgery and Director of the Diabetes Surgery Center at Weill Cornell Medical College-New York Presbyterian Hospital
  • Lee M. Kaplan*, MD, Ph.D., Director, Massachusetts General Hospital (MGH) Weight Center and Associate Professor of Medicine at Harvard Medical School

"This forum highlights the important role innovative thinking and collaboration play in the fight against obesity - a fight that will require treatment options beyond surgical and pharmaceutical solutions available today to win," said Karen Licitra, Company Group Chairman, Ethicon Endo-Surgery, Inc., who introduced the session. "Ethicon Endo-Surgery is committed to supporting research into the underlying metabolic effect bariatric surgery has on co-morbid conditions, such as Type 2 diabetes, heart disease and cancer. We know bariatric surgery is effective but we don't know how or why. We believe this basic science will help us better understand which patients are likely to respond to different therapies, as well as help us develop new therapies that are less invasive and more cost-effective."

Dr. Seeley discussed his research on the biology of obesity and the role of the central nervous system in regulating food intake, body weight and fat tissue. He said new treatments for Type 2 diabetes and obesity may be able to alter the function of fat tissue or change the signaling that takes place between fat tissue and the brain to better regulate satiety and the storage of calories. Dr. Seeley is the recipient of the 2009 American Diabetes Association Outstanding Scientific Achievement Award.

Dr. Kaplan presented on "The Remarkable Physiology of Metabolic Surgery." He discussed potential mechanisms by which metabolic surgery affects Type 2 diabetes. He cited three primary ways: 1. weight loss, 2. decreased nutrient intake or 3. changes in GI physiology or signaling independent of weight loss and decreased nutrient intake, but that this last mechanism appears to be limited to gastric bypass. He said gastric bypass has the ability to reset the body's energy "set point" at a lower body mass index (BMI) and that the central nervous system plays a large role in the metabolic effects and weight loss from the surgery.

Dr. Rubino discussed metabolic surgery as a primary treatment for Type 2 diabetes and presented data on diabetes remission after metabolic surgery even before weight loss occurs. He asserted that remission results from more than gastric restriction and weight loss and that the surgically rearranged intestine and other factors related to the proximal bowel may contribute to the pathophysiology of type 2 diabetes. He raised the question if BMI alone in Type 2 diabetes patients should not be a determinant for who has access to metabolic surgery, as BMI may not enable consideration of other critical patient specific health factors (e.g., uncontrolled/poorly controlled diabetes). Dr. Rubino indicated that these data support the need for additional research and dialogue between appropriate healthcare stakeholders.

Dr. Schauer summed up the session with a review of the American Diabetes Association (ADA) 2009 Treatment Guidelines that for the first time said, "bariatric surgery should be considered for adults with BMI >/- 35 kg/m2 and type 2 diabetes, especially if the diabetes is difficult to control with lifestyle and pharmacologic therapy." He pointed out that the ADA Guidelines stated that "bariatric surgery has been shown to lead to near or complete normalization of glycemia in 55-95% of patients with type 2 diabetes, depending on the surgical procedure."

"Diabetes is a chronic progressive disease," said Dr. Schauer. "BMI is easy to measure and a pretty good indication of the percentage of body fat, so we should just use it as a marker but not a rule."

About Ethicon Endo-Surgery

Ethicon Endo-Surgery, Inc., a Johnson & Johnson company, develops and markets advanced medical devices for minimally invasive and open surgical procedures, focusing on procedure-enabling devices for the interventional diagnosis and treatment of conditions in general and bariatric surgery, as well as gastrointestinal health, gynecology and surgical oncology.

Ethicon Endo-Surgery Commitment to Metabolic Surgery

In 2008, Ethicon Endo-Surgery partnered with the University of Cincinnati (UC) through a significant three-year investment to gain a better understanding of the basic biology behind obesity. Ethicon Endo-Surgery engineers and UC researchers will work together to find new solutions for treating obesity and related conditions, including diabetes.

In 2009, the company also signed a three-year research contract with Massachusetts General to deconstruct and understand the how and why behind the outcomes of the Roux-en-Y gastric bypass procedure.

More information can be found at www.ethiconendo.com.

*Paid consultant to Ethicon Endo-Surgery


'/>"/>
SOURCE Ethicon Endo-Surgery, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Related medicine news :

1. NuSil Technology Acquires Pharmaceutical Antifoam (Simethicone) Business from Bluestar Silicones
2. Ethicon Endo-Surgery Novel Investigational Notes and SSL Devices Featured in 15 Presentations at Sages
3. FDA Grants Ethicon Endo-Surgery Approval of Its IDE Application to Commence Study of Notes Toolbox(TM)
4. Board-Certified Bariatric Surgeon, Trace Curry, MD Places First Next-Generation Ethicon Endo-Surgery REALIZE™ Adjustable Gastric Band-C in Ohio
5. ETHICON Launches the Latest Innovation in Hernia Repair Platform; PROCEED(TM) Ventral Patch (PVP(TM) Device)
6. Board-Certified Bariatric Surgeon, Trace Curry, MD Places First Next-Generation Ethicon Endo-Surgery REALIZE™ Adjustable Gastric Band-C in Ohio
7. ETHICON Completes Divestiture of Professional Wound Care Business to One Equity Partners
8. ETHICON Receives Offer from One Equity Partners to Purchase Professional Wound Care Business
9. Ethicon Endo-Surgery Submits Application to FDA for Approval of the SEDASYS(TM) System - the First Computer-Assisted Personalized Sedation System
10. Leading Independent Analyst Firm States Silver Creek Systems Holds A Virtual Monopoly In Delivering Advanced Product Data Quality Capabilities
11. President Obama Holds Roundtable Discussion on Health Reform at Children's National Medical Center
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... ... June 27, 2016 , ... "FCPX editors can now reveal ... Final Cut Pro X," said Christina Austin - CEO of Pixel Film Studios. ... Cut Pro X users can now reveal the media of their split screens ...
(Date:6/27/2016)... ... June 27, 2016 , ... TopConsumerReviews.com recently awarded their highest five-star rating ... Millions of individuals in the United States and Canada wear eyeglasses. Once considered to ... correct vision and make a fashion statement. Even celebrities use glasses as a way ...
(Date:6/26/2016)... North Carolina (PRWEB) , ... June 26, 2016 , ... ... release of a new product that was developed to enhance the health of felines. ... for centuries. , The two main herbs in the PawPaws Cat Kidney Support ...
(Date:6/25/2016)... ... , ... Austin residents seeking Mohs surgery services, can now turn to Dr. ... Russell Peckham for medical and surgical dermatology. , Dr. Dorsey brings specialization to include ... in Mohs Micrographic Surgery completed by Dr. Dorsey was under the direction of Glenn ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern ... Laude and his M.D from the David Geffen School of Medicine at UCLA. He ... Los Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 2016  In a startling report released today, National Safety ... lacking a comprehensive, proven plan to eliminate prescription opioid overdoses. ... how states are tackling the worst drug crisis in recorded U.S. ... Kentucky , New Mexico , ... Of the 28 failing states, three – Michigan ...
(Date:6/23/2016)... Research and Markets has announced the addition of ... their offering. The current ... environment for MedImmune to enter. The US ageing population creates ... drive considerable growth for effective anti-influenza medications. The introduction of ... but development is still in its infancy. ...
(Date:6/23/2016)... and BOGOTA, Colombia , June 23, 2016  Astellas today announced the establishment of Astellas Farma ... as the company,s second affiliate in Latin America . ... ... Astellas Farma Colombia ... ...
Breaking Medicine Technology: