Navigation Links
Estrogen reduces aggression in breast cancer
Date:2/14/2011

very considerable increase in the survival rates of patients. It had also been proposed that the number of cancerous stem cells is correlated with the aggressiveness of the tumour: The greater the percentage of breast cancer stem cells, the greater the aggressiveness and the worse, thereby, its prognosis.

"To our surprise, what we have seen is that oestrogen reduces the proportion of breast stem cells which means a mechanism for explaining this better prognosis observed with tumours that express the oestrogen receptor. That is, those tumours expressing the oestrogen receptor are less aggressive, better differentiated and thus have a better prognosis", explained Ms Mara Vivanco, leader of the research team.

Ms Vivanco believes that this study presents a new functional aspect of oestrogen, due to its capacity for acting in a different way depending on cellular type.

In the opinion of the CIC bioGUNE researcher, this study "has set out the molecular bases for understanding the direct effect of oestrogen on the proportion of stem cells, whether in healthy or cancerous tissue and the fact that the oestrogen receptor is an excellent prognostic marker". Moreover, this means there is an explanation for a number of clinical observations, for example: the high levels of oestrogen in the blood of postmenopausal patients being associated with less aggressive tumours; the fact that little-differentiated tumours contain more cancerous stem cells, in turn associated with the degree of the tumour, the absence of the oestrogen receptor and low survival rate; and the observed benefit of lactation attributed to a greater differentiation in the breast.

The researchers consider that the new study represents a highly important step, opening new doors to developing tools for the prevention of breast cancer.


'/>"/>

Contact: Oihane Lakar
o.lakar@elhuyar.com
34-943-363-040
Elhuyar Fundazioa
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Anti-estrogen medication reduces risk of dying from lung cancer
2. UNC researchers investigate estrogen to prevent depression and cardiovascular disease
3. Estrogen May Play Role in Rising Rates of Head, Neck Cancer
4. Estrogen-Only Hormone Therapy May Reduce Breast Cancer Risk for Some
5. Estrogen replacement therapy speeds ovarian cancer growth, new study reports
6. Tendon Injuries May Be Linked to Estrogen Levels in Female Athletes
7. Team to study health effects of botanical estrogens
8. Estrogen not associated with lung cancer incidence and mortality among postmenopausal women
9. Breast cancer cells regulate multiple genes in response to estrogen-like compounds
10. Scientists find link between estrogen metabolism pathway and breast cancer risk
11. Researchers find key to getting estrogens benefits without cancer risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/26/2014)... 2014 Parker & Sons, Inc. ... in heating, cooling and plumbing contractor services throughout ... services in 2014 with regard to air-conditioning systems. ... is known for its incredibly hot summers. Working ... intricacies and details of a wide variety of ...
(Date:12/25/2014)... 2014 The click strand ... strength and durability. Today, the business announces a ... valid until Jan. 30, 2015. , Click strand ... hardwood. BambooFlooringChina.com is a well-known brand in the ... to find a reliable bamboo flooring supplier. , ...
(Date:12/25/2014)... 2014 Product liability lawsuits filed in ... ( http://www.consumerinjurylawyers.com/DePuy/ ) continue to move forward in federal ... issued in the U.S. District Court, Northern District of ... open conference on January 7, 2015, at the Paul ... West Palm Beach, Florida. The Conference is scheduled to ...
(Date:12/25/2014)... Recently, Dylan Queen, a famous online company supplying ... of discounted prom dresses, most of which are priced ... the company, the promotion is valid until Jan. 22, ... the UK market. , The prom dresses in this ... styles: A-line strapless, empire strapless chiffon, one shoulder, floor-length, ...
(Date:12/25/2014)... sells many bamboo products and the business is famous ... announces big discounts on its bamboo mats , which ... the world’s leader in bamboo flooring. According to the ... 2015. , The bamboo mats are made from well-treated ... the bamboo strips for the mats are boiled and ...
Breaking Medicine News(10 mins):Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 2Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 3Health News:BambooFlooringChina.com: click strand woven bamboo flooring promotion valid until Jan. 30, 2015. 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 3Health News:Dylan Queen: Cheap Prom Dresses for the UK Market 2Health News:Various Styles of Bamboo Mats in Many Colors from BambooFlooringChina.com 2
... solutions to its established Life Sciences North American practice building ... ... operations., PHILADELPHIA, Nov. 13 Business & Decision, (http://www.businessdecision.com ) ... business will focus on providing,Pharmaceutical, Biotechnology, Medical Device and CRO companies ...
... for humans, researchers say , TUESDAY, Nov. 13 ... prostate tumor growth, possibly because fewer carbohydrates leads to ... "This study showed that cutting carbohydrates may slow tumor ... confirmed in human clinical trials, it has huge implications ...
... chronic pancreatitis, especially tropical calcific pancreatitis (TCP), where the ... and cause enormous tissue destruction. The exact mechanism of ... to understand the initial event so that stone formation ... to the pancreatic tissue. One such study was recently ...
... Use May Not Influence Recommendation -,- Higher Percentage ... WASHINGTON, Nov. 13 The landmark "Life...supplemented",Healthcare ... three,quarters of U.S. physicians (79 percent) and nurses ... study also shows that an almost,equal number -- ...
... Researchers have,long been examining the link between oral health ... it was Hippocrates who suggested that,removing an infected tooth ... connected to the rest of the body and that ... a prognosis, treat and intervene on a,host of diseases. ...
... FUNCTION , New research reveals that a persons socioeconomic ... function. After reviewing 20 years of medical literature regarding ... and adults, researchers from LDS Hospital and the University ... negative correlation between the two, even after adjusting for ...
Cached Medicine News:Health News:Business & Decision Brings its eClinical Life Sciences Industry offering to North America 2Health News:Business & Decision Brings its eClinical Life Sciences Industry offering to North America 3Health News:Low-Carb Diet May Slow Prostate Tumor Growth 2Health News:The most important candidate genes for pancreatic stone formation 2Health News:Study Finds Physicians and Nurses Both Take and Recommend Dietary Supplements 2Health News:Study Finds Physicians and Nurses Both Take and Recommend Dietary Supplements 3Health News:Study Finds Physicians and Nurses Both Take and Recommend Dietary Supplements 4Health News:Study Finds Physicians and Nurses Both Take and Recommend Dietary Supplements 5Health News:PDA Stresses Link Between Oral Health and Overall Health 2Health News:PDA Stresses Link Between Oral Health and Overall Health 3
(Date:12/22/2014)... Apnea Sciences ( www.apneasciences.com ) announced it ... Aliso Viejo , California.  Jimmy Fallon , ... and worldwide expansion, a new facility with expanded infrastructure ... snore cure have exceeded our expectations and thus required ... in 23 countries and will be increasing to 39 ...
(Date:12/22/2014)... 22, 2014   TRU-D SmartUVC LLC, producers ... robot, announced today that the General Services Administration has ... 2019.   This newly formed agreement will ... of government purchasers, including Department of Veteran Affairs and ... Security contacts purchasing solutions for the Ebola effort in ...
(Date:12/22/2014)... LUXEMBOURG , Dec. 22, 2014  ConvaTec, a ... Paul Moraviec has been appointed Interim Chief Executive Officer ... Mr. Moraviec succeeds Ken Berger .  "The Board ... service in leading ConvaTec over the past three years," ... Board of Directors.  "We are confident that the company ...
Breaking Medicine Technology:TRU-D SmartUVC LLC Awarded General Services Administration Contract to Expand Government Customer Base 2ConvaTec Names Paul Moraviec Interim CEO Effective December 22, 2014 2
... Ohio, Oct. 31, 2011 Cardinal Health ... Blue with Neu-Thera® sterile latex powder-free surgical gloves with ... The newest addition to the Protexis™ ... gloves are made from natural rubber latex and contain ...
... 31, 2011 Haemonetics Corporation (NYSE: HAE ) ... million, up 8%, net income of $13.9 million, down 35%, ... costs and contingent consideration income, adjusted second quarter net income ... was $0.72, down 9%.  Excluding currency impacts, net revenue was ...
Cached Medicine Technology:Cardinal Health Introduces New Protexis™ Latex Blue With Neu-Thera® Surgical Gloves 2Cardinal Health Introduces New Protexis™ Latex Blue With Neu-Thera® Surgical Gloves 3Haemonetics Reports 8% Revenue Growth for Second Quarter of Fiscal 2012, Adjusted Earnings Per Share of $0.72 and Updates Previously Provided Full Year Earnings Guidance 2Haemonetics Reports 8% Revenue Growth for Second Quarter of Fiscal 2012, Adjusted Earnings Per Share of $0.72 and Updates Previously Provided Full Year Earnings Guidance 3Haemonetics Reports 8% Revenue Growth for Second Quarter of Fiscal 2012, Adjusted Earnings Per Share of $0.72 and Updates Previously Provided Full Year Earnings Guidance 4Haemonetics Reports 8% Revenue Growth for Second Quarter of Fiscal 2012, Adjusted Earnings Per Share of $0.72 and Updates Previously Provided Full Year Earnings Guidance 5Haemonetics Reports 8% Revenue Growth for Second Quarter of Fiscal 2012, Adjusted Earnings Per Share of $0.72 and Updates Previously Provided Full Year Earnings Guidance 6Haemonetics Reports 8% Revenue Growth for Second Quarter of Fiscal 2012, Adjusted Earnings Per Share of $0.72 and Updates Previously Provided Full Year Earnings Guidance 7Haemonetics Reports 8% Revenue Growth for Second Quarter of Fiscal 2012, Adjusted Earnings Per Share of $0.72 and Updates Previously Provided Full Year Earnings Guidance 8Haemonetics Reports 8% Revenue Growth for Second Quarter of Fiscal 2012, Adjusted Earnings Per Share of $0.72 and Updates Previously Provided Full Year Earnings Guidance 9Haemonetics Reports 8% Revenue Growth for Second Quarter of Fiscal 2012, Adjusted Earnings Per Share of $0.72 and Updates Previously Provided Full Year Earnings Guidance 10Haemonetics Reports 8% Revenue Growth for Second Quarter of Fiscal 2012, Adjusted Earnings Per Share of $0.72 and Updates Previously Provided Full Year Earnings Guidance 11Haemonetics Reports 8% Revenue Growth for Second Quarter of Fiscal 2012, Adjusted Earnings Per Share of $0.72 and Updates Previously Provided Full Year Earnings Guidance 12Haemonetics Reports 8% Revenue Growth for Second Quarter of Fiscal 2012, Adjusted Earnings Per Share of $0.72 and Updates Previously Provided Full Year Earnings Guidance 13Haemonetics Reports 8% Revenue Growth for Second Quarter of Fiscal 2012, Adjusted Earnings Per Share of $0.72 and Updates Previously Provided Full Year Earnings Guidance 14
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: