Navigation Links
Estrogen and progesterone receptor isoforms expression in the stomach of Mongolian gerbils
Date:10/31/2008

A research article to be published on October 7,2008 in the World Journal of Gastroenterology addresses this question. The research team led by Dr. Camacho-Arroyo from Universidad Nacional Autnoma de Mxico used commercially available antibodies to detect estrogen and progesterone receptors isoforms in female gerbil stomach. They also evaluated the effects of E2 and E2+P4 in the regulation of these receptors. As it has been previously reported that stomach has steroidogenic activity, and that both estradiol (E2) and progesterone (P4) play differential roles in response to gastric injury and H. pylori infection, it was important to be able to detect these proteins in Mongolian gerbils stomach.

Specific bands for estrogen receptor (ER)-alpha (68 kDa), progesterone receptor (PR)-A (85 kDa) and PR-B (120 kDa) were detected, unfortunately they were unable to detect ER-beta isoform. The identity of the receptors was defined by using rat uteri samples along with the Mongolian gerbil uteri. This is important because Mongolian gerbils sex steroid receptors have not been sequenced at the gene or protein levels. The detection of these receptors with antibodies raised against other specie receptors suggests high conservation of the specific epitopes among species. The validation of commercially available antibodies for ER and PR in Mongolian gerbils adds applicability to the results of this study.

The regulation of ER and PR by E2 and P4 was first defined in target organs in the reproductive tract, and after several studies, there is enough evidence that this regulation is tissue specific and it is associated to the function of E2 and P4 in every particular tissue. ER and PR expression regulation in Mongolian gerbils has not been reported previously. The lack of regulation of ER and PR in gerbil uteri deserved further investigation. The differential regulation in gastric antrum and corpus suggests differential roles of these receptors in the different g
'/>"/>

Contact: Lin Tian
wjg@wjgnet.com
86-105-908-0039
World Journal of Gastroenterology
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Estrogen flooding our rivers, Université de Montréal study
2. Estrogen Cream No Match for Sun-Damaged Skin
3. Estrogen May Have Preventive Role in Womens Schizophrenia
4. Team discovers new inhibitors of estrogen-dependent breast cancer cells
5. Estrogen therapy helps or hurts the brain depending on reproductive status
6. Anti-estrogen drug therapy reduces risk of invasive breast cancer in older women
7. Previously unseen switch regulates breast cancer response to estrogen
8. Estrogen therapy increases benign breast disease risk
9. Estrogen Supplements May Raise Odds of Benign Breast Disease
10. New study finds adverse effects of estrogen replacement therapy are related to the dose
11. Mitochondria play role in pathogenesis of AD and estrogen-induced neuroprotection
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... As reported by Wood TV 8 in the article ... seen a nearly 500-person increase in heroin related overdose deaths ... between 1999 and 2002, the toll increased to 728 during ... states, drug users in Michigan have turned to heroin after ... the price of both substances, noting that an 80-milligram pill ...
(Date:7/25/2014)... 2014 (HealthDay News) -- The human brain can preserve ... a new study finds. Although dehydration significantly ... have found that the brain compensates by increasing the ... "This research has helped us understand a lot more ... in extreme conditions," study first author Steven Trangmar, a ...
(Date:7/25/2014)... 25, 2014 Ticket Down is ... Milan tickets in Berkeley at California Memorial Stadium. With ... fans of football, the organizers of the 2014 Guinness International ... teams to North America. With teams representing La Liga, English ... bring some of the best football players from around the ...
(Date:7/25/2014)... This is a professional and ... Galactooligosaccharides (GOS) industry in Global and China. ... industry, including definitions, applications and industry chain structure. ... are provided with a focus on history, developments, ... comparison between the international and Chinese situation is ...
(Date:7/25/2014)... July 25, 2014 (HealthDay News) -- Babies seem to ... By the time women are 34 weeks pregnant, ... their mother,s voice reciting a familiar nursery rhyme, the ... source of sensory stimulation in the developing fetus," Charlene ... of Florida,s College of Nursing, said in a university ...
Breaking Medicine News(10 mins):Health News:Rise in Heroin Use, Overdose Deaths in Michigan 2Health News:Human Brain Has Coping Mechanism for Dehydration 2Health News:Real Madrid vs. Inter Milan Tickets Berkeley: Ticket Down Slashes Ticket Prices on Guinness International Champions Cup Tickets at California Memorial Stadium 2Health News:Real Madrid vs. Inter Milan Tickets Berkeley: Ticket Down Slashes Ticket Prices on Guinness International Champions Cup Tickets at California Memorial Stadium 3Health News:GOS Market (Galacto-oligosaccharides) Development in Global & China Regions Now Available at DeepResearchReports.com 2Health News:GOS Market (Galacto-oligosaccharides) Development in Global & China Regions Now Available at DeepResearchReports.com 3Health News:Rhymes Reveal Evidence of Learning in the Womb 2
... such as not using condoms or having sex with ... sexually transmitted diseases, but perhaps not as much as ... researchers say. , The findings, which UF and University ... Sexually Transmitted Diseases , could help health-care providers ...
... 3 eDiets.com, Inc. (Nasdaq: DIET ... healthy lifestyle solutions, today announced that it received a notice ... of the Company,s listed securities has fallen below $35 million, ... Market, in compliance with NASDAQ Marketplace Rule 4310(c)(3)(B). The ...
... less apt to include adult smokers, study finds, , , FRIDAY, ... more secondhand smoke than their wealthier counterparts, a new study ... "poor kids are far more likely to live with multiple ... Michael Weitzman, a professor of pediatrics at New York University. ...
... awarded $15,000 for envisioning the ,home of the future, ... At the Embedded Systems Conference (ESC) Silicon Valley 2009 ... of the Microsoft Windows Embedded SPARKs Will Fly developer ... innovation among the embedded hobbyist and academic communities. The ...
... the growing number of Pennsylvanians who are trying to ... in federal cigarette taxes, the Department of Health today ... www.determinedtoquit.com ."The average smoker makes between five and ... have support are more likely to succeed," said Secretary ...
... risk from overdosing following the surgery, study found , , FRIDAY, ... to one in five deaths among people who have had ... relieve lower back pain. , Among this group, middle-aged ... risk of either accidental or suicidal analgesic poisoning compared to ...
Cached Medicine News:Health News:Partner behavior better predicts STD risks 2Health News:Partner behavior better predicts STD risks 3Health News:eDiets.com(R) Receives NASDAQ Notice Regarding Market Value of Listed Securities 2Health News:eDiets.com(R) Receives NASDAQ Notice Regarding Market Value of Listed Securities 3Health News:Poor Kids Exposed to More Secondhand Smoke 2Health News:Poor Kids Exposed to More Secondhand Smoke 3Health News:Microsoft Windows Embedded Announces Winner of SPARKs Will Fly Developer Contest 2Health News:Pennsylvania Department of Health Helps Smokers Trying to Quit in Wake of Federal Cigarette Tax Hike 2Health News:Post-Op Painkillers Tied to Deaths After Spinal Fusion 2
(Date:7/25/2014)... July 25, 2014 /PRNewswire-iReach/ -- "Australia Capsule Endoscopy Systems ... the Australia Capsule Endoscopy Systems market. The report provides ... and average prices (in US dollars) within market segments: ... , Capsule Endoscopes , Capsule Endoscopy Data ... The report also provides company shares and distribution shares ...
(Date:7/25/2014)... July 25, 2014  Smile Train and its technology ... their Virtual Surgery Simulator among leading global health innovations ... place in Washington, D.C. at ... "Smile Train is honored to be ... community of innovators in health and medicine that TEDMED ...
(Date:7/25/2014)... /PRNewswire-iReach/ -- Full Service CRO WCCT Global ... President of Business Development. Peter has been in the ... of different business development positions with some of the ... related to business development/sales management and marketing.  The experience ... him a key and strategic asset to WCCT Global ...
Breaking Medicine Technology:Australia Capsule Endoscopy Systems Market Analysis and Forecast to 2020 2Australia Capsule Endoscopy Systems Market Analysis and Forecast to 2020 3Australia Capsule Endoscopy Systems Market Analysis and Forecast to 2020 4Australia Capsule Endoscopy Systems Market Analysis and Forecast to 2020 5Smile Train and BioDigital Selected to Showcase Virtual Surgery Simulator in The Hive at TEDMED 2014 2Smile Train and BioDigital Selected to Showcase Virtual Surgery Simulator in The Hive at TEDMED 2014 3Contract Research Organization WCCT Global Welcomes Peter Nieto as Vice President of Business Development 2
... LAS VEGAS, Oct. 26 Cord Blood America, Inc ... ), the umbilical cord blood stem cell preservation company ... cells to families nationwide and internationally, today announced its Chairman, ... Company,s stem cell collection business in China in an interview ...
... sectors -- HONG KONG, Oct. 26 /PRNewswire-Asia/ -- ... ... if (typeof(lpUnit)==,undefined,) var lpUnit=,PRN,; --> ... ""; BitlyCB.alertResponse = function(data) { var s = ,; var first_result; // Results are keyed by longUrl, so we ...
Cached Medicine Technology:Cord Blood America Updates Its Stem Cell Collection Business in China 2Global Sources launches integrated, multi-channel offerings for three fast-growing export sectors 2Global Sources launches integrated, multi-channel offerings for three fast-growing export sectors 3Global Sources launches integrated, multi-channel offerings for three fast-growing export sectors 4Global Sources launches integrated, multi-channel offerings for three fast-growing export sectors 5Global Sources launches integrated, multi-channel offerings for three fast-growing export sectors 6Global Sources launches integrated, multi-channel offerings for three fast-growing export sectors 7Global Sources launches integrated, multi-channel offerings for three fast-growing export sectors 8Global Sources launches integrated, multi-channel offerings for three fast-growing export sectors 9
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: