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Estrogen Cream No Match for Sun-Damaged Skin
Date:9/16/2008

of estrogen-receptor expression. Estradiol activity seemed to be the same, regardless of whether the skin had or had not been damaged by the sun.

The study was partially supported by Pfizer.

The authors acknowledge that treating volunteers for more than two weeks might have yielded different results in sun-exposed skin areas; additional studies would be needed to test this.

"What makes a hormone a hormone is that it is made in one place but works somewhere else in the body," said Dr. Doris Day, an attending physician in dermatology at Lenox Hill Hospital in New York City. "It's like a light switch, it's small but, when you turn it on, the whole room lights up. Estradiol cream is like a little switch, but we're only just beginning to understand the different parts of the body it affects and how it affects them. This is putting the science behind the anecdote."

More information

The American Academy of Dermatology has sun-safety tips.



SOURCES: Laure Ritti, Ph.D., research investigator, department of dermatology, University of Michigan Medical School, Ann Arbor; Doris Day, M.D., attending physician, dermatology, Lenox Hill Hospital, New York City; September 2008, Archives of Dermatology


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