Navigation Links
Erectile Dysfunction Tied to Long-Term Narcotic Use in Men
Date:5/15/2013

By Serena Gordon
HealthDay Reporter

WEDNESDAY, May 15 (HealthDay News) -- If you're a man, the pain-killing medications known as opioids may do more than relieve pain -- they may also put a damper on your sex life.

A new study found that men who were prescribed medications for erectile dysfunction or low testosterone levels were more likely to be taking opioid (narcotic) medications for chronic back pain.

"People who have persistent pain problems need to know that a potential side effect of long-term opioid use may be erectile dysfunction," said lead study author Dr. Richard Deyo, a clinical investigator for the Kaiser Permanente Center for Health Research in Portland, Ore. "This is not a well-known potential side effect among patients, and it should be considered when thinking about treatment."

Deyo also noted, however, that "the nature of this study as an observational study limits our ability to make a causal [cause-and-effect] inference. Opioid use and erectile dysfunction seem to go together, but we have to be cautious about saying one causes the other."

Results of the study were published in the May issue of the journal Spine.

More than 4 million people use opioids on a regular basis, Deyo said. Commonly prescribed opioids include hydrocodone, oxycodone and morphine. In this study, use of opioids was considered long-term if patients used them for more than 120 days, or more than 90 days if more than 10 prescriptions were filled for the drugs.

The study included data on about 11,000 men who had back pain. In that group, more than 900 received medications for erectile dysfunction or testosterone replacement. Those who were given prescriptions for erectile dysfunction medications or testosterone were older than those who didn't get such prescriptions. They also were more likely to have depression and other health conditions.

And those who were taking erectile dysfunction medications or testosterone tended to be smokers or users of sedative medications, according to the study.

Erectile dysfunction drug prescriptions were for sildenafil (Viagra), tadalafil (Cialis) and vardenafil (Levitra).

Age was the most significant factor in getting a prescription for erectile dysfunction, according to the study. Men between the ages of 60 and 69 were 14 times more likely to receive a prescription for an erectile dysfunction medication than men who were between 18 and 29.

After adjusting the data to account for other possible factors, including age, the researchers found that men who took opioid pain medications for long periods were about 50 percent more likely to take erectile dysfunction medications or testosterone replacement therapy.

Dr. Daniel Shoskes, a professor of urology at the Cleveland Clinic's Glickman Urological and Kidney Institute, said the study doesn't prove that the pain medications cause the erectile dysfunction.

"A direct association between long-term opioid use and [erectile dysfunction] has not been clearly defined," said Shoskes, who was not involved in the study. "The reason these men were having [erectile dysfunction] could be related to the pain or the things that are causing the pain. You can't conclude from this study that opioid use causes [erectile dysfunction]."

Study author Deyo said there's evidence that men who stop taking opioids after using them for a short time will see an improvement in erectile dysfunction, but he said it's not clear if the same is true after long-term use.

Deyo added that opioids can be effective for short-term use, but there's "growing evidence that long-term opioid use may not be effective for chronic pain. The body compensates for taking long-term pain medications, and changes in the brain and spinal cord may make people more sensitive over time."

Effective alternatives include a tailored exercise program and cognitive behavioral therapy designed to help reduce people's fear of pain, Deyo said.

Shoskes said other factors that contribute to erectile dysfunction include diabetes, heart disease, peripheral vascular disease and alcohol use. He said this study may prompt doctors who treat men with chronic pain to ask about erectile dysfunction, although he said it's not clear from this study whether the erectile medications were helpful for these men.

More information

Learn more about erectile dysfunction from the U.S. National Library of Medicine.

SOURCES: Richard Deyo, M.D., clinical investigator, Kaiser Permanente Center for Health Research, and professor of family medicine, Oregon Health and Science University, Portland; Daniel Shoskes, M.D., professor and staff physician, department of urology, Glickman Urological and Kidney Institute, Cleveland Clinic, Ohio; May 2013 Spine


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Long-term use of prescription painkillers for back pain linked to erectile dysfunction in men
2. Most Men With Erectile Dysfunction Dont Seem to Get Treatment
3. Most men with erectile dysfunction remain untreated, say US scientists
4. Erectile Dysfunction Clinic Set to Open April 1st in Maryland
5. Common erectile dysfunction drug not helpful for heart failure patients, study finds
6. The Elator Announces it's Recognition from The Sinclair Institute for its Penile Support Device for Men Suffering from Erectile Dysfunction
7. Erectile Dysfunction May Signal Hidden Heart Disease
8. Erectile dysfunction drug also helps men ejaculate and orgasm
9. Advanced Male Medical Center Provides New and Effective Therapies to Treat Erectile Dysfunction
10. Grief is not a disease, but cancer is -- what about erectile dysfunction?
11. Miriam researchers urge physicians to ask younger men about erectile dysfunction symptoms
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Erectile Dysfunction Tied to Long-Term Narcotic Use in Men
(Date:2/12/2016)... ... 2016 , ... The law firm of Morrow, Morrow, Ryan & Bassett is ... these scholarships is to encourage applicants to pursue a degree in their field of ... parishes. , “We have available jobs in St. Landry and Evangeline Parishes that ...
(Date:2/12/2016)... ... February 12, 2016 , ... CDRH Enforcement Trends: , Back to the Future , ... , As Winston Churchill said, “Those who don’t learn from history are doomed to ... expect when they come knocking this year. But that takes time. , Take a ...
(Date:2/12/2016)... (PRWEB) , ... February 12, 2016 , ... As a ... hectic schedule, a demanding job, and no time to decompress, Rabinowitz found herself drawn ... herself to meditation for its impact on her life, implementing a 20-minute-per-day meditation practice ...
(Date:2/12/2016)... ... February 12, 2016 , ... ... at Zuckerberg San Francisco General Hospital on April 5-7. The series is a ... create new habits. The workshops cover a broad range of topics, including coaching ...
(Date:2/12/2016)... ... , ... Fisher House Foundation Chairman and CEO Kenneth Fisher joined Governor Brian ... president Scott Bensing, and Peggy Kearns Director, VA Southern Nevada Healthcare System yesterday to ... will be the first Fisher House in Nevada, and will provide free lodging for ...
Breaking Medicine News(10 mins):
(Date:2/12/2016)... 2016  Sequent Medical, Inc. announced today that it ... the safety and effectiveness of the WEB™ Aneurysm Embolization ... aneurysms.  Prof Laurent Spelle , MD, Head of ... France and Principal Investigator of the CLARYS ... and Germany.  Although patients with ruptured aneurysms ...
(Date:2/12/2016)... and SEOUL, South Korea ... Biosys­tems Menarini and Macrogen, Inc. today announced they ... and innovative procedures for precision medicine in cancer. ... Silicon Biosystems, DEPArray™ digital-sorting technology with Macrogen,s high-throughput ... tests certified under the Clinical Laboratory Improvement Amendments ...
(Date:2/12/2016)... MILTON, Ontario , Feb. 12, 2016  Aralez ... specialty pharmaceutical company, today announced the Company will ring the ... Square, New York at 4:00 ... the formation of Aralez. Adrian Adams ... will be held 3:50 to 4:00 p.m. ET.  A ...
Breaking Medicine Technology: