Navigation Links
Epilepsy Drugs May Raise Fracture Risk in Older Adults

TUESDAY, Jan. 11 (HealthDay News) -- Epilepsy drugs increase older adults' risk for bone fractures, a new study shows.

Canadian researchers analyzed the medical records of 15,792 people 50 and older who'd had non-traumatic fractures between April 1996 and March 2004. Each person was matched with up to three people who'd never had a fracture, for a total of 47,289 people to serve as controls.

The researchers also looked at the participants' use of epilepsy drugs, including carbamazepine (Carbatrol, Epitol, Tegretol), clonazepam (Klonopin), ethosuximide (Zarontin), gabapentin (Gabarone, Neurontin), phenobarbital (Luminal), phenytoin (Dilantin, Phenytek) and valproic acid (Depakene, Depakote).

All but one of the drugs was associated with an increased risk for fractures. The greatest risk was among people taking phenytoin and carbamazepine. Valproic acid was the only drug not linked with an increased chance of fractures.

The results, published in the January issue of Archives of Neurology, were similar for people taking just one epilepsy drug and those taking more than one.

"In conclusion, our study showed that most anti-epileptic drugs except for valproic acid are associated with an increased likelihood of non-traumatic fracture in individuals aged 50 year or older," wrote Dr. Nathalie Jette, of the University of Calgary's Foothill Hospital, and colleagues in a journal news release.

They called for further research into the effects of epilepsy drugs on bone health.

More information

The American Academy of Family Physicians has more about epilepsy.

-- Robert Preidt

SOURCE: JAMA/Archives journals, news release, Jan. 10, 2011

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Link between signaling molecules could point way to therapies for epilepsy, stroke, other diseases
2. Epilepsy Found to Be More Common in U.S. Than Thought
3. Researchers: Pay more attention to epilepsy
4. Death Rates Higher for Those With Lasting Epilepsy: Study
5. Common Epilepsy Drug Taken During Pregnancy Might Raise Spina Bifida Risk
6. Women Taking Certain Epilepsy Drugs Can Safely Breast-Feed, Study Suggests
7. Study Sees Link Between Epilepsy, Infertility
8. Great strides in treatment of stroke, headache, epilepsy
9. Epilepsy Drugs Dont Raise Suicide Risk, Study Shows
10. Not All Epilepsy Drugs Raise Suicide Risk: Study
11. Brain Injury May Raise Soldiers Epilepsy Risk
Post Your Comments:
Related Image:
Epilepsy Drugs May Raise Fracture Risk in Older Adults
(Date:12/1/2015)... (PRWEB) , ... December 02, 2015 , ... Ruth Pearson ... brutal lupus flare-up. Unable to walk without assistance and quickly losing hope of recovering ... then a miracle happened. , Pearson was attending a women’s retreat when she experienced ...
(Date:12/1/2015)... ... December 01, 2015 , ... The Multiple System Atrophy Coalition ... funds for Multiple System Atrophy (MSA) research, timed today to coincide with Giving Tuesday ... from patients including their ability to work and be productive, to do simple daily ...
(Date:12/1/2015)... , ... December 01, 2015 , ... Royal River Natural ... new study that found post-menopausal women who took the nutritional supplement creatine, along with ... who trained but did not take creatine. , The report is part of the ...
(Date:12/1/2015)... , ... December 01, 2015 , ... ... leadless pacemakers in the U.S. and is the only hospital in the region ... largest clinical data presentation of transcatheter pacing patients were revealed recently at a ...
(Date:12/1/2015)... ... 01, 2015 , ... December 1, 2015 -- InstantLabs is ... growing product line of food safety and seafood fraud prevention tools. , The ... allow InstantLabs to offer fast, reliable species identification for the four most popular ...
Breaking Medicine News(10 mins):
(Date:12/1/2015)... Russia has always been a ... new drugs registered in Europe in 2015 were ... Russia has always been a country of choice ... in Europe in 2015 were tested in phase ... Russia has always been a country of choice for global ...
(Date:12/1/2015)... , Dec. 1, 2015 CytRx Corporation (NASDAQ: ... specializing in oncology, today announced that it has reached ... pivotal global Phase 3 clinical trial of aldoxorubicin in ... originally estimated to be completed in Q1 2016. The Phase ... under a Special Protocol Assessment from the FDA at ...
(Date:12/1/2015)... 1, 2015  The migration to value-based care ... care plans that help patients stay healthy and ... be digitally enabled, incorporate care guidelines and be ... They will also allow all stakeholders to collaborate ... is optimal. That is the vision, however, research ...
Breaking Medicine Technology: