Navigation Links
Epigenetics emerges powerfully as a clinical tool

The research team led by Manel Esteller, director of the Cancer Epigenetics and Biology Program at the Bellvitge Biomedical Research Institute (IDIBELL), professor of genetics at the University of Barcelona and ICREA researcher, has updated the latest findings in applied epigenetics in a review paper published in Nature Reviews Genetics.

There is a growing need for better biomarkers that allow early detection of human diseases, especially cancer. The markers can improve primary prevention, diagnosis and prognosis of disease. Furthermore, it is possible to predict which may be more effective treatment according to patient characteristics, which is known by the name of personalized medicine.

Genetic tests complementary to traditional methods have been used to improve the approach to various diseases, but in the last ten years Epigenetics has hardly emerged to help solve these clinical situations, as highlighted by the article. Epigenetics is the discipline for the study of the chemical changes in our genetic material and the same regulatory proteins. The most known epigenetic mark is the addition of a methyl group to the DNA.

The study notes that the last decade two tests based on the methylation of two genes, MGMT and GSTP1, have been proved vital in predicting brain tumours sensitive to the temozolomide drug and in distinguishing prostate cancer compared benign growth, respectively. Dr. Esteller points out that "the most exciting thing is that they are currently being identified new epigenetic biomarkers for predicting the performance and weaknesses of tumours at a fast pace." In this sense, the coordinator of the study cites the recent identification of epigenetic alterations in predictive genes as response to new generation drugs in leukaemia and the fact that obtaining a "picture" of the DNA methylation pattern can expose unknown tumours that previously had a very poor prognosis.

Contact: Ral Toran
IDIBELL-Bellvitge Biomedical Research Institute

Page: 1

Related medicine news :

1. Spice ingredient in curry emerges as promising basis for an Alzheimers disease medicine
2. Yet Another Tick-Borne Illness Emerges in U.S.
3. First targeted nanomedicine to enter human clinical studies
4. Clinical insight improves treatment with new lung cancer drug
5. Clinical news alert from the American Academy of Orthopaedic Surgeons
6. NYU Langone experts present research, clinical advances at neurosurgeons meeting
7. Kroenke honored for outstanding contributions in clinical research training
8. Awards celebrate clinical research that can improve health and alleviate suffering
9. Association for Psychological Science, SAGE launch Clinical Psychological Science
10. URMC clinical trial tests new regimen for hypertension
11. Analysis Finds Clinical Trials Often Small, of Poor Quality
Post Your Comments:
Related Image:
Epigenetics emerges powerfully as a clinical tool
(Date:10/13/2017)... ... October 13, 2017 , ... The American Board of ... its next President and Chief Executive Officer, succeeding Dr. James C. Puffer upon his ... July 1, 2018 until Dr. Puffer’s retirement at the end of 2018. Upon assuming ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... alumni Hannah Randall, PharmD ‘17, and Jennifer Huggins, PharmD ’17, along with ... for the primary prevention of cardiovascular diseases during the 15th Annual Women’s ...
(Date:10/13/2017)... ... October 13, 2017 , ... Many families have long-term insurance ... care insurance companies have a waiver for care if the client has a cognitive ... the family pays for care, is often waived, so the benefits from their insurance ...
(Date:10/13/2017)... NJ (PRWEB) , ... October 13, 2017 , ... Global ... at scenic Alexandria Park in Milford, NJ. This free event, sponsored by Global ... physical activity. The fun run is geared towards children of all ages; it ...
(Date:10/13/2017)... VA (PRWEB) , ... October 13, 2017 , ... ... of DevOps and Agile Software Development, has been awarded a contract by the ... Blanket Purchase Agreement (BPA) aims to accelerate the enterprise use of Agile methodologies ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... -- Halo Labs announces the European launch of their new low ... MIBio 2017 in Cambridge, U.K on October ... biopharmaceutical samples with unprecedented speed and sensitivity while using far less ... Imaging. ... analysis system ...
(Date:9/27/2017)... 2017  Commended for their devotion to personalized service, SMP ... number one in the South Florida Business Journal,s 50 Fastest-Growing ... yearly list, the national specialty pharmacy has found its niche.  ... will soon be honored by SFBJ as the 2017 Power ... Set to receive his award in October, Bardisa said of ...
(Date:9/23/2017)... Sept. 22, 2017 Janssen Biotech, Inc. (Janssen) ... letter from the U.S. Food and Drug Administration (FDA) ... sirukumab for the treatment of moderately to severely active ... clinical data are needed to further evaluate the safety ... active RA. ...
Breaking Medicine Technology: