Navigation Links
Epigenetics emerges powerfully as a clinical tool
Date:9/12/2012

The research team led by Manel Esteller, director of the Cancer Epigenetics and Biology Program at the Bellvitge Biomedical Research Institute (IDIBELL), professor of genetics at the University of Barcelona and ICREA researcher, has updated the latest findings in applied epigenetics in a review paper published in Nature Reviews Genetics.

There is a growing need for better biomarkers that allow early detection of human diseases, especially cancer. The markers can improve primary prevention, diagnosis and prognosis of disease. Furthermore, it is possible to predict which may be more effective treatment according to patient characteristics, which is known by the name of personalized medicine.

Genetic tests complementary to traditional methods have been used to improve the approach to various diseases, but in the last ten years Epigenetics has hardly emerged to help solve these clinical situations, as highlighted by the article. Epigenetics is the discipline for the study of the chemical changes in our genetic material and the same regulatory proteins. The most known epigenetic mark is the addition of a methyl group to the DNA.

The study notes that the last decade two tests based on the methylation of two genes, MGMT and GSTP1, have been proved vital in predicting brain tumours sensitive to the temozolomide drug and in distinguishing prostate cancer compared benign growth, respectively. Dr. Esteller points out that "the most exciting thing is that they are currently being identified new epigenetic biomarkers for predicting the performance and weaknesses of tumours at a fast pace." In this sense, the coordinator of the study cites the recent identification of epigenetic alterations in predictive genes as response to new generation drugs in leukaemia and the fact that obtaining a "picture" of the DNA methylation pattern can expose unknown tumours that previously had a very poor prognosis.


'/>"/>
Contact: Ral Toran
comunicacio@idibell.cat
IDIBELL-Bellvitge Biomedical Research Institute
Source:Eurekalert  

Page: 1

Related medicine news :

1. Spice ingredient in curry emerges as promising basis for an Alzheimers disease medicine
2. Yet Another Tick-Borne Illness Emerges in U.S.
3. First targeted nanomedicine to enter human clinical studies
4. Clinical insight improves treatment with new lung cancer drug
5. Clinical news alert from the American Academy of Orthopaedic Surgeons
6. NYU Langone experts present research, clinical advances at neurosurgeons meeting
7. Kroenke honored for outstanding contributions in clinical research training
8. Awards celebrate clinical research that can improve health and alleviate suffering
9. Association for Psychological Science, SAGE launch Clinical Psychological Science
10. URMC clinical trial tests new regimen for hypertension
11. Analysis Finds Clinical Trials Often Small, of Poor Quality
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Epigenetics emerges powerfully as a clinical tool
(Date:5/3/2016)... ... May 03, 2016 , ... AvePoint, ... release of DocAve 6 Service Pack (SP) 7, the enterprise-class infrastructure ... 2016 and take advantage of the platform’s latest features – whether in an ...
(Date:5/3/2016)... ... May 03, 2016 , ... LunchSkins is changing the future of ... of single-use, throw away plastic baggies. The mission-driven bags give back to global leaders ... “The LunchSkins mission is all about reducing global plastic waste and we’ve ...
(Date:5/2/2016)... ... May 03, 2016 , ... ... FDA approved sSOIP telemedicine stethoscope software that enables the stethoscope stream to go ... PCP-SSP and works with RNK’s flagship PCP-USB stethoscope. , Remote auscultation involves two ...
(Date:5/2/2016)... ... ... As directed by its board of directors during its April 26 meeting, The ... nurse practitioners (CNP) to practice to the full scope of their license without the ... and 3,600 hours. , In addition, HAP supports CNPs who are licensed in another ...
(Date:5/2/2016)... (PRWEB) , ... May 02, 2016 , ... ... educational website to help consumers better understand life insurance throughout various life stages. ... including an easy-to-use life insurance needs calculator and content specific to the times ...
Breaking Medicine News(10 mins):
(Date:4/29/2016)... ORANGE COUNTY, Calif. , April 29, 2016 ... technology industry is projected to shift from systems ... can replace all types of modality CRT Medical ... set-up." Although there are a host of foreseeable ... a serious concern; will existing modalities have to ...
(Date:4/29/2016)... 2016 Interview ... Sanofi, leader mondial et diversifié ... pour le premier trimestre 2016. Le ... commente les résultats du premier trimestre ... le reste de l,année. ...
(Date:4/28/2016)... 2016   Click here for supplemental information ... DPLO), the nation,s largest independent specialty pharmacy, announced ... to acquire Valley Campus Pharmacy, Inc., doing business ... specialty pharmacy that provides individualized patient care, based ... In 2015, TNH generated approximately $400 million in ...
Breaking Medicine Technology: