Navigation Links
Epigenetics emerges powerfully as a clinical tool
Date:9/12/2012

The research team led by Manel Esteller, director of the Cancer Epigenetics and Biology Program at the Bellvitge Biomedical Research Institute (IDIBELL), professor of genetics at the University of Barcelona and ICREA researcher, has updated the latest findings in applied epigenetics in a review paper published in Nature Reviews Genetics.

There is a growing need for better biomarkers that allow early detection of human diseases, especially cancer. The markers can improve primary prevention, diagnosis and prognosis of disease. Furthermore, it is possible to predict which may be more effective treatment according to patient characteristics, which is known by the name of personalized medicine.

Genetic tests complementary to traditional methods have been used to improve the approach to various diseases, but in the last ten years Epigenetics has hardly emerged to help solve these clinical situations, as highlighted by the article. Epigenetics is the discipline for the study of the chemical changes in our genetic material and the same regulatory proteins. The most known epigenetic mark is the addition of a methyl group to the DNA.

The study notes that the last decade two tests based on the methylation of two genes, MGMT and GSTP1, have been proved vital in predicting brain tumours sensitive to the temozolomide drug and in distinguishing prostate cancer compared benign growth, respectively. Dr. Esteller points out that "the most exciting thing is that they are currently being identified new epigenetic biomarkers for predicting the performance and weaknesses of tumours at a fast pace." In this sense, the coordinator of the study cites the recent identification of epigenetic alterations in predictive genes as response to new generation drugs in leukaemia and the fact that obtaining a "picture" of the DNA methylation pattern can expose unknown tumours that previously had a very poor prognosis.


'/>"/>
Contact: Ral Toran
comunicacio@idibell.cat
IDIBELL-Bellvitge Biomedical Research Institute
Source:Eurekalert  

Page: 1

Related medicine news :

1. Spice ingredient in curry emerges as promising basis for an Alzheimers disease medicine
2. Yet Another Tick-Borne Illness Emerges in U.S.
3. First targeted nanomedicine to enter human clinical studies
4. Clinical insight improves treatment with new lung cancer drug
5. Clinical news alert from the American Academy of Orthopaedic Surgeons
6. NYU Langone experts present research, clinical advances at neurosurgeons meeting
7. Kroenke honored for outstanding contributions in clinical research training
8. Awards celebrate clinical research that can improve health and alleviate suffering
9. Association for Psychological Science, SAGE launch Clinical Psychological Science
10. URMC clinical trial tests new regimen for hypertension
11. Analysis Finds Clinical Trials Often Small, of Poor Quality
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Epigenetics emerges powerfully as a clinical tool
(Date:8/16/2017)... ... August 16, 2017 , ... The Data ... today that it was acquired by Advantage Solutions. The Data Council’s IX-ONE ... members include the industry’s leading suppliers, brokers, distributors and retailers. The Data Council ...
(Date:8/16/2017)... Va. (PRWEB) , ... August 16, 2017 , ... ... America (BIAA) is collaborating with a New England student to educate the public ... to acclaim in 2016 for launching the first-ever National Concussion Awareness Day. , ...
(Date:8/16/2017)... New York (PRWEB) , ... August 16, 2017 , ... ... could minimize its appearance with diet and exercise. In fact, cellulite can't always be ... a safer and more effective treatment available to select physicians nationwide. Dr. Kenneth Rothaus ...
(Date:8/16/2017)... ... 16, 2017 , ... Modern Consulting Insurance & Financial Services ... once again with Boys & Girls Clubs of Greater Kansas City, the agency ... own American Idol. With all proceeds benefitting local worthy causes, donations may be ...
(Date:8/16/2017)... ... August 16, 2017 , ... ... received a three-year grant totaling $975,000, renewing its funding from the Health Resources ... Services. , This funding marks, the fourth time the HRSA administration has renewed ...
Breaking Medicine News(10 mins):
(Date:8/1/2017)... Aug. 1, 2017   CerSci Therapeutics , a ... Texas , has received notice from the National ... of Health (NIH) that it has been awarded a ... over $650,000 in 2017 with an additional $1,000,000 to ... New Drug application of their lead non-opioid drug candidate ...
(Date:7/28/2017)... --EnvoyHealth, a Diplomat company, has partnered with Compliance Meds ... a technology designed to improve patient medication adherence. ... solutions and services that help track and improve patients, ... LITE offers medication monitoring and control for patients and ... Records date and time of bottle ...
(Date:7/26/2017)... BEACH, Fla. , July 26, 2017 ... of enrollment of our clinical trial evaluating Altemia TM ... Cell Anemia (SCA) and Sickle Cell Disease (SCD). The ... to evaluate the efficacy and safety of Altemia TM ... trial is conducted under US IND 125274. ...
Breaking Medicine Technology: