TARRYTOWN, N.Y., Dec. 4 /PRNewswire-FirstCall/ -- EpiCept Corporation (Nasdaq and OMX Nordic Exchange: EPCT) today announced that it will be presenting new clinical data for Ceplene (histamine dihydrochloride) at the upcoming 49th Annual Meeting of the American Society of Hematology (ASH), taking place in Atlanta, Georgia from December 8-11, 2007. Ceplene is EpiCept's lead oncology product candidate under late stage review by the European Medicines Evaluation Agency (EMEA) for the remission maintenance treatment and prevention of relapse of patients with Acute Myeloid Leukemia (AML) in first remission.
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The results to be presented at the meeting include an analysis of the long-term outcomes of AML patients enrolled in the pivotal Phase III Ceplene study. The new data compares the effects of post-consolidation immunotherapy with histamine dihydrochloride (HDC) in conjunction with low dose interleukin- 2 (IL-2) on leukemia-free survival and overall survival compared to the current standard of care, which is no treatment, at five years post initiation of therapy.
The following poster presentations will be given by EpiCept on Sunday,
December 9, 2007 from 9:00 a.m. to 8:00 p.m. Eastern Time at Hall B3 and B4
in the Georgia World Congress Center.
Poster # 36
Title: "Post-consolidation Immunotherapy with Histamine Dihydrochloride
and Interleukin-2 in AML: Long Term Follow-Up of Leukemia-Free Survival
and Overall Survival."
Session Name: Acute Myeloid Leukemias - Therapy, excluding
Transplantation.
Presenter: Mats L. Brune, et al; University of Goteborg, Goteborg,
Sweden.
Poster # 499
Title: "Histamine Dihydrochloride Maintains Cytoxic Effector Lymphocyte
Function and Viability under Conditions of Oxidative Stress."
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