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Enzyme action could be target for diabetes, heart disease treatments
Date:11/16/2010

at cell differentiation and the finding that elevated HDAC9 levels are associated with adipose tissue dysfunction in obesity are extremely interesting and novel findings," he continues.

Chatterjee's team is pursuing studies to understand how diet regulates HDAC9 levels in fat tissue and how HDAC9 up-regulation can be prevented during diet-induced obesity through pharmacological means.

"Our findings may help lead researchers to targeted therapies that may prevent the development of obesity-related disorders in humans."


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Contact: Katie Pence
katie.pence@uc.edu
513-558-4561
University of Cincinnati Academic Health Center
Source:Eurekalert

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