Navigation Links
Engineers improve blood testing technology with smartphone app, hand-held biosensor
Date:9/6/2012

KINGSTON, R.I. September 6, 2012 A team of engineers and students at the University of Rhode Island has developed an advanced blood-testing technology that incorporates a smartphone application, a hand-held biosensor and a credit card-sized cartridge to provide rapid, accurate biological analysis and wireless communication of test results.

This new lab-on-a-chip technology improves upon a previous system announced by the URI team in 2011 that generated enthusiasm among many sectors of the health care industry. Several patents are pending on the invention.

"We went from a shoebox-size device last year to a hand-held device with several additional capabilities," said Mohammad Faghri, URI professor of mechanical engineering and the lead researcher on the project. "The smartphone app turns the system on, monitors the assay, and sends the results securely back to your phone or to your doctor, all in about 20 minutes."

Faghri said the advancements make the new system faster, more accurate, easier to use, and much less expensive than previous versions. For example, the fluorescence sensor in the hand-held unit costs less than $10 compared to the $3,200 sensor in the shoe-box system.

"It's accuracy, compactness and low cost are a result of an innovative contact imaging system that serves as the fluorescence detector and the central piece of the fluid feedback control system," Faghri said.

To operate the system, users place a drop of blood from a finger prick on a disposable plastic polymer cartridge and insert it into the hand-held biosensor. The blood travels through the cartridge in tiny channels 500 microns wide to a detection site where it reacts with preloaded reagents enabling the sensor to detect certain biomarkers of disease.

"Today when you go to the lab to have a blood test, they take vials of liquid from you and you have to wait sometimes days to get the results," Faghri said. "With our system, you can have your blood tested when you walk into the doctor's office and the results will be ready before you leave. Or you can do it at home and have the results sent to your doctor in real time."

Faghri even envisions having astronauts at the International Space Station test their blood and sending the results wirelessly back to Earth.

The first cartridges the researchers developed focus on the detection of C-reactive proteins in the blood, a preferred method for helping doctors assess the risk of cardiovascular and peripheral vascular diseases. Additional cartridges can be engineered to detect biomarkers of other diseases, including the beta amyloid protein that can be used as a predictor of Alzheimer's disease. The device can also be developed to detect virulent pathogens, like HIV, hepatitis B and H1N1 (swine) flu.

One of the most important advancements of the new device is that it can conduct the test on whole blood rather than blood plasma. The cartridge filters out the cellular components of blood, as well as some of the abundant non-target proteins that often interfere with the detection of the targeted protein.

The third generation of the device, currently in development, will put the entire lab on paper, eliminating the need for active pumping of blood and reagents through the cartridge.


'/>"/>
Contact: Todd McLeish
tmcleish@uri.edu
401-874-7892
University of Rhode Island
Source:Eurekalert

Related medicine news :

1. Rice University student engineers automate limb lengthening for kids
2. UCLA bioengineers discover single cancer cell can produce up to 5 daughter cells
3. Worlds fastest camera, created by UCLA engineers, used to detect rogue cancer cells
4. UT Dallas engineers identify material that reduces pollution from diesel engines
5. Clinical insight improves treatment with new lung cancer drug
6. Improved Stem Cell Line May Avoid Tumor Risk: Study
7. Normalizing tumor blood vessels improves delivery of only the smallest nanomedicines
8. Exercise improves quality of life during breast cancer treatment
9. IU, Regenstrief automated system aims to improve child health
10. Swallowing exercises linked with short-term improvement among patients with head and neck cancer
11. MU receives national award for using mind-body approach to improve health
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... The International Association ... standards of excellence for the field of eating disorders, announces the opening of ... 2018 in Orlando, Florida at the Omni Resort at ChampionsGate. , ...
(Date:10/13/2017)... ... October 13, 2017 , ... Apple Rehab Shelton Lakes , which ... evacuation of the facility as part of a disaster drill on October 3rd. , ... and Shelton City Emergency Manager, as well as the Connecticut Long Term Care ...
(Date:10/13/2017)... ... October 13, 2017 , ... Global Healthcare Management’s 4th Annual Kids ... Milford, NJ. This free event, sponsored by Global Healthcare Management’s CEO, Jon Letko, ... run is geared towards children of all ages; it is a non-competitive, non-timed event, ...
(Date:10/13/2017)... ... 2017 , ... “The Journey: From the Mountains to the Mission Field”: the ... in the Philippines. “The Journey: From the Mountains to the Mission Field” is the ... She has taught all ages and currently teaches a class of ladies at her ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest and fastest ... to open a flagship location in Covington, LA at 401 N. U.S. Highway 190, ... next to Office Depot in the Holiday Square shopping center. Its location allows it ...
Breaking Medicine News(10 mins):
(Date:10/7/2017)... --  Provista, a proven leader in the supply ... power, today announced a new resource area on Provistaco.com ... is the online home for case studies, articles on ... releases, slideshows and events. ... at their fingertips, viewers can also watch short videos ...
(Date:10/4/2017)... to the Centers for Disease Control and Prevention (CDC), influenza vaccination ... is helping communities across Massachusetts , Connecticut ... flu shots through the end of the month. *Some exclusions ... ... shot is by the end of October, according to the Centers for ...
(Date:10/2/2017)... , Oct. 2, 2017  Eli Lilly and ... financial results for the third quarter of 2017 on ... conference call on that day with the investment community ... The conference call will begin at 9 ... can access a live webcast of the conference call ...
Breaking Medicine Technology: