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Engineers improve blood testing technology with smartphone app, hand-held biosensor
Date:9/6/2012

KINGSTON, R.I. September 6, 2012 A team of engineers and students at the University of Rhode Island has developed an advanced blood-testing technology that incorporates a smartphone application, a hand-held biosensor and a credit card-sized cartridge to provide rapid, accurate biological analysis and wireless communication of test results.

This new lab-on-a-chip technology improves upon a previous system announced by the URI team in 2011 that generated enthusiasm among many sectors of the health care industry. Several patents are pending on the invention.

"We went from a shoebox-size device last year to a hand-held device with several additional capabilities," said Mohammad Faghri, URI professor of mechanical engineering and the lead researcher on the project. "The smartphone app turns the system on, monitors the assay, and sends the results securely back to your phone or to your doctor, all in about 20 minutes."

Faghri said the advancements make the new system faster, more accurate, easier to use, and much less expensive than previous versions. For example, the fluorescence sensor in the hand-held unit costs less than $10 compared to the $3,200 sensor in the shoe-box system.

"It's accuracy, compactness and low cost are a result of an innovative contact imaging system that serves as the fluorescence detector and the central piece of the fluid feedback control system," Faghri said.

To operate the system, users place a drop of blood from a finger prick on a disposable plastic polymer cartridge and insert it into the hand-held biosensor. The blood travels through the cartridge in tiny channels 500 microns wide to a detection site where it reacts with preloaded reagents enabling the sensor to detect certain biomarkers of disease.

"Today when you go to the lab to have a blood test, they take vials of liquid from you and you have to wait sometimes days to get the results," Faghri said. "With our system, you ca
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Contact: Todd McLeish
tmcleish@uri.edu
401-874-7892
University of Rhode Island
Source:Eurekalert

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