Navigation Links
Engineers developing new cements to heal spinal fractures
Date:10/28/2007

New research could offer hope for victims of the most devastating spinal injuries - typically those caused in car crashes.

Biological cements to repair burst fractures of the spine are being developed and tested in a major new collaborative project between the University of Leeds and Queens University Belfast. The team has been awarded just under 500,000 by the Engineering and Physical Sciences Research Council (EPSRC) to develop and examine the effects of novel cement materials for the treatment of burst fractures.

Bone cements, similar to those used in joint replacement surgery, are already being used to strengthen damaged vertebrae of patients with diseases such as osteoporosis, in a procedure known as vertebroplasty, but burst fractures to the spine, injuries often sustained in major impact accidents and falls, are much more difficult to treat. They account for over 1,000 emergency NHS admissions each year and often require highly complex, invasive surgery and a long stay in hospital.

This type of fracture causes the vertebra to burst apart and in severe cases fragments of bone can be pushed into the spinal cord, says Dr Ruth Wilcox of Leeds Institute of Medical and Biological Engineering. Surgeons may be able to join bone fragments together and stabilize the spine with the use of metal screws and rods, but patients with these injuries are often in a really bad way, so the less invasive the treatment, the better.

The project team at Queens has expertise in developing and testing synthetic biomaterials for the repair of bone defects. These materials can be delivered to the fracture site by injection and mimic the chemical composition of bone itself, says Dr Fraser Buchanan, from the Universitys School of Mechanical and Aerospace Engineering.

At Leeds the team has expertise in computational modelling of the spine and will be able to provide Queens with data to assist in the development of novel biomaterials and to simulate how they will perform in patients.

Statistically, burst fractures are seen more in younger people, and not enough is currently known about the long term consequences of using existing cements for the treatment of this type of injury. There is evidence to show that some patients with osteoporosis, who tend to be older, can develop fractures in the vertebrae adjacent to those treated with vertebroplasty.

We think this may be because current cements are stiffer than the bone itself causing an imbalance in the way the spine bears weight. This may increase loading on the neighbouring vertebrae, which can lead to further damage says Dr Wilcox.

Clearly we need to develop biomaterials that more closely match the properties of real bone. This project offers the perfect opportunity to use the range of complimentary skills of this grouping to predict the effects of newly developed cements and even incorporate biological agents to assist the bodys own healing process, added Dr Buchanan.

To be able to use bone cements for burst fractures would be a major leap forward. It would be simpler, quicker and much less invasive for the patient, reducing both recovery times and NHS costs.


'/>"/>

Contact: Jo Kelly
jokelly@campuspr.co.uk
44-011-325-89880
University of Leeds  
Source:Eurekalert

Related medicine news :

1. Back injury cured by engineers
2. New antibiotic already developing resistance
3. Identifying The Risks Of Developing Schizophrenia
4. Patients With Severe Hemophilia At Risk Of Developing Osteoporosis
5. Risk Of Developing Arthritis
6. Periodontal disease may amass the risk of developing Type 2 diabetes
7. Developing HIV fighter
8. Diabetes cases could double in developing countries in next 30 years
9. Antibiotics Found To Increase The Risk Of Developing Breast Cancer
10. The Effectiveness Of Cancer Drug In Women At Risk Of Developing Cancer
11. Men Who at Risk Of Developing Prostate Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Engineers developing new cements to heal spinal fractures
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was out ... family verbally and physically. , “When something upset him, he couldn’t control his emotions,” remembers ... would throw rocks at my other children and say he was going to kill them. ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. ... accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas of orthodontics, ... and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic ...
(Date:6/24/2016)... ... ... People across the U.S. are sharpening their pencils and honing their writing ... which patients and their families pay tribute to a genetic counselor by nominating him ... Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. , In April, Genome ...
(Date:6/24/2016)... ... June 24, 2016 , ... Puradigm® & Innovative Solutions ... initiated cultivation and processing operations at its production facility, and opened its first ... is the manufacturer of a complete system of proactive air and surface purification ...
(Date:6/24/2016)... ... ... Venture Construction Group (VCG) sponsors Luke’s Wings 5th Annual ... Country Club at 1201 Rockville Pike, Rockville, Maryland, 20852. The event raised funds ... been wounded in battle and their families. Venture Construction Group is a 2016 Silver ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)...  VMS Rehab Systems, Inc. ( www.vmsrehabsystemsinc.com ) reported ... required to build a strong and stable market for ... on the OTC Markets-pink current trading platform. ... are seeing an anomaly in market trading activities that ... the Company, but shareholders and market players as well. ...
(Date:6/24/2016)... SAN FRANCISCO, Calif. , June 24, 2016 ... GBT ), a biopharmaceutical company developing novel therapeutics ... significant unmet needs, today announced the closing of ... shares of common stock, at the public offering ... shares in the offering were offered by GBT. ...
(Date:6/24/2016)... ALEXANDRIA, Va. , June 24, 2016 ... a set of recommendations that would allow ... information (HCEI) with entities that make formulary and coverage ... determine the "value" of new medicines. The ... that does not appear on the drug label, a ...
Breaking Medicine Technology: