Navigation Links
Engineers: New sensor could help treat, combat diabetes, other diseases
Date:1/21/2010

GAINESVILLE, Fla. A tiny new sensor could provide fresh, inexpensive diagnosis and treatment methods for people suffering from a variety of diseases.

University of Florida engineers have designed and tested versions of the sensor for applications ranging from monitoring diabetics' glucose levels via their breath to detecting possible indicators of breast cancer in saliva. They say early results are promising particularly considering that the sensor can be mass produced inexpensively with technology already widely used for making chips in cell phones and other devices.

"This uses known manufacturing technology that is already out there," said Fan Ren, a professor of chemical engineering and one of a team of engineers collaborating on the project.

The team has published 15 peer-reviewed papers on different versions of the sensor, most recently in this month's edition of IEEE Sensors Journal. In that paper, members report integrating the sensor in a wireless system that can detect glucose in exhaled breath, then relay the findings to health care workers. That makes the sensor one of several non-invasive devices in development to replace the finger prick kits widely used by diabetics.

Tests with the sensor contradict long-held assumptions that glucose levels in the breath are too small for accurate assessment, Ren said. That's because the sensor uses a semiconductor that amplifies the minute signals to readable levels, he said.

"Instead of poking your finger to get the blood, you can just breathe into it and measure the glucose in the breath condensate," Ren said.

In the IEEE paper and other published work, the researchers report using the sensor to detect pH or alkalinity levels in the breath, a technique that could help people who suffer from asthma better identify and treat asthma attacks as well as calibrate the sensitivity of the glucose sensor. The engineers have used other versions to experiment with picking up indicators of breast cancer in saliva, and pathogens in water and other substances.

As with the finger prick standard, tests for pH, breast or cancer indicators typically already exist, but they are often cumbersome, expensive or time-consuming, Ren said. For example, the current technique for measuring pH in a patient's breath requires the patient to blow into a tube for 20 minutes to collect enough condensate for a measurement.

At 100 microns, or 100 millionths of a meter, the UF sensor is so small that the moisture from one breath is enough to get a pH or glucose concentration reading in under five seconds, Ren said.

Ren said the sensors work by mating different reactive substances with the semiconductor gallium nitride commonly used in amplifiers in cell phones, power grid transmission equipment and other applications.

If targeting cancer, the substance is an antibody that is sensitive to certain proteins identified as indicative of cancer. If the target is glucose, the reactive molecules are composed of zinc oxide nanorods that bind with glucose enzymes.

Once the reaction happens, "the charge on the semiconductor devices changes, and we can detect that change," Ren said.

While the sensor is not as acutely sensitive as those that rely on nanotechnology, the manufacturing techniques are already widely available, Ren said. The cost is as little as 20 cents per chip, but goes up considerably when combined with applications to transmit the information wirelessly to computers or cell phones. The entire wireless-chip package might cost around $40, he said, although that cost could be cut in half with mass production.

The team has patented or is in the process of patenting several elements of the technology, and several companies have expressed interest in pursuing the research, Ren said.


'/>"/>

Contact: Aaron Hoover
ahoover@ufl.edu
352-392-0186
University of Florida
Source:Eurekalert

Related medicine news :

1. Nanosensors Spot Early Signs of Cancer
2. EASe Funhouse Video Game Helps Children with Autism Learn to Improve Sensory Processing
3. Researchers unlock the sound of learning by linking sensory and motor systems
4. Force Sensor Manufacturer, Tekscan, Inc. Wins "Best of Tradeshow" for MDM Minneapolis Exhibition
5. Loadstar Sensors Launches DI-1000z - Wireless Load Cell Interface
6. Image Sensors 2009 Offers Promotional Discount on Machine Vision and Wireless Power Summits
7. Sensory Research Center Benefit Concert Yields Scholarships for Autistic Children
8. The Sensory Research Center (SRC) Offers 2 for 1 Tickets for Benefit Concert Supporting Autism, Downs Syndrome, Cerebral Palsy and Other Disabilities.
9. Pitt researchers harness carbon nanomaterials for drug delivery systems, oxygen sensors
10. A super sensor for cancer and CSIs
11. Image Sensors 2009 Announces Final Program and New Interactive Brochure
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/12/2017)... Wis. (PRWEB) , ... October 12, 2017 , ... ... standard products to meet the demand of today’s consumer and regulatory authorities worldwide. ... of probiotic experts and tested to meet the highest standard. , These ...
(Date:10/12/2017)... ... October 12, 2017 , ... The American College of Medical Informatics ... PhD, FACMI, during the Opening Session of AMIA’s Annual Symposium in Washington, D.C. AMIA’s ... of Morris F. Collen, a pioneer in the field of medical informatics, this prestigious ...
(Date:10/12/2017)... ... 12, 2017 , ... Information about the technology: , Otomagnetics ... enable prevention of a major side effect of chemotherapy in children. Cisplatin and ... For cisplatin, hearing loss is FDA listed on-label as a dose limiting toxicity. ...
(Date:10/12/2017)... ... October 12, 2017 , ... HMP , a leader ... a 2017 Folio Magazine Eddie Digital Award for ‘Best B-to-B Healthcare Website.’ Winners were ... 11, 2017. , The annual award competition recognizes editorial and design excellence across a ...
(Date:10/12/2017)... ... October 12, 2017 , ... On Saturday, October 21, the Health ... Miles by Moonlight to raise money for the American Heart Association Heart Walk. Teams ... Teams will work together to keep their treadmills moving for 5 hours. Treadmills will ...
Breaking Medicine News(10 mins):
(Date:10/4/2017)... SEOUL, South Korea , Oct. 4, 2017 /PRNewswire/ ... launched its next-generation CPR training aide "cprCUBE" on Kickstarter. ... of chest compression during cardiac arrests with better efficiency ... patient-mannequins. It also offers real-time feedback on efficacy of ... The crowdfunding campaign has a goal to raise ...
(Date:10/4/2017)... Mass. , Oct. 4, 2017 ... of single-use, self-contained, illuminating medical devices, today announced ... National Health Surveillance Agency (or Agência Nacional de ... The first single-use, cordless surgical retractor with integrated ... provides optimal access, illumination and exposure of a ...
(Date:10/2/2017)... , Oct. 2, 2017  Eli Lilly and Company ... results for the third quarter of 2017 on Tuesday, ... call on that day with the investment community and ... The conference call will begin at 9 a.m. ... access a live webcast of the conference call through ...
Breaking Medicine Technology: