Navigation Links
Engineers: New sensor could help treat, combat diabetes, other diseases
Date:1/21/2010

GAINESVILLE, Fla. A tiny new sensor could provide fresh, inexpensive diagnosis and treatment methods for people suffering from a variety of diseases.

University of Florida engineers have designed and tested versions of the sensor for applications ranging from monitoring diabetics' glucose levels via their breath to detecting possible indicators of breast cancer in saliva. They say early results are promising particularly considering that the sensor can be mass produced inexpensively with technology already widely used for making chips in cell phones and other devices.

"This uses known manufacturing technology that is already out there," said Fan Ren, a professor of chemical engineering and one of a team of engineers collaborating on the project.

The team has published 15 peer-reviewed papers on different versions of the sensor, most recently in this month's edition of IEEE Sensors Journal. In that paper, members report integrating the sensor in a wireless system that can detect glucose in exhaled breath, then relay the findings to health care workers. That makes the sensor one of several non-invasive devices in development to replace the finger prick kits widely used by diabetics.

Tests with the sensor contradict long-held assumptions that glucose levels in the breath are too small for accurate assessment, Ren said. That's because the sensor uses a semiconductor that amplifies the minute signals to readable levels, he said.

"Instead of poking your finger to get the blood, you can just breathe into it and measure the glucose in the breath condensate," Ren said.

In the IEEE paper and other published work, the researchers report using the sensor to detect pH or alkalinity levels in the breath, a technique that could help people who suffer from asthma better identify and treat asthma attacks as well as calibrate the sensitivity of the glucose sensor. The engineers have used other versions to experiment with picking up indicators of breast cancer in saliva, and pathogens in water and other substances.

As with the finger prick standard, tests for pH, breast or cancer indicators typically already exist, but they are often cumbersome, expensive or time-consuming, Ren said. For example, the current technique for measuring pH in a patient's breath requires the patient to blow into a tube for 20 minutes to collect enough condensate for a measurement.

At 100 microns, or 100 millionths of a meter, the UF sensor is so small that the moisture from one breath is enough to get a pH or glucose concentration reading in under five seconds, Ren said.

Ren said the sensors work by mating different reactive substances with the semiconductor gallium nitride commonly used in amplifiers in cell phones, power grid transmission equipment and other applications.

If targeting cancer, the substance is an antibody that is sensitive to certain proteins identified as indicative of cancer. If the target is glucose, the reactive molecules are composed of zinc oxide nanorods that bind with glucose enzymes.

Once the reaction happens, "the charge on the semiconductor devices changes, and we can detect that change," Ren said.

While the sensor is not as acutely sensitive as those that rely on nanotechnology, the manufacturing techniques are already widely available, Ren said. The cost is as little as 20 cents per chip, but goes up considerably when combined with applications to transmit the information wirelessly to computers or cell phones. The entire wireless-chip package might cost around $40, he said, although that cost could be cut in half with mass production.

The team has patented or is in the process of patenting several elements of the technology, and several companies have expressed interest in pursuing the research, Ren said.


'/>"/>

Contact: Aaron Hoover
ahoover@ufl.edu
352-392-0186
University of Florida
Source:Eurekalert

Related medicine news :

1. Nanosensors Spot Early Signs of Cancer
2. EASe Funhouse Video Game Helps Children with Autism Learn to Improve Sensory Processing
3. Researchers unlock the sound of learning by linking sensory and motor systems
4. Force Sensor Manufacturer, Tekscan, Inc. Wins "Best of Tradeshow" for MDM Minneapolis Exhibition
5. Loadstar Sensors Launches DI-1000z - Wireless Load Cell Interface
6. Image Sensors 2009 Offers Promotional Discount on Machine Vision and Wireless Power Summits
7. Sensory Research Center Benefit Concert Yields Scholarships for Autistic Children
8. The Sensory Research Center (SRC) Offers 2 for 1 Tickets for Benefit Concert Supporting Autism, Downs Syndrome, Cerebral Palsy and Other Disabilities.
9. Pitt researchers harness carbon nanomaterials for drug delivery systems, oxygen sensors
10. A super sensor for cancer and CSIs
11. Image Sensors 2009 Announces Final Program and New Interactive Brochure
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2017)... ... April 28, 2017 , ... Datta Endoscopic Back ... joined the revolutionary endoscopic practice under Dr. Datta. Patel is a Board Certified ... The patented, revolutionary eDiscSculpt Technique created and used by Datta Endoscopic is unlike ...
(Date:4/28/2017)... ... April 28, 2017 , ... From April ... of Urgent Care Medicine will host industry leaders for the annual spring Convention ... those in the industry adapt to the issues currently affecting urgent care and ...
(Date:4/28/2017)... ... ... Bill Howe started his sewer and drain company in 1980 focusing heavily ... team, the Bill Howe brand was born and they began cultivating their mission to ... the San Diego community in which they worked, lived and were raising their daughters. ...
(Date:4/28/2017)... ... April 28, 2017 , ... ... North East region. Côté has 20+ years of experience within the beauty industry, ... worked with an array of high-end cosmetic brands, retail brands and outlets in ...
(Date:4/28/2017)... ... April 28, 2017 , ... NuevaCare, a leading home care agency based ... and Palo Alto, is proud to announce information upgrades to its blog in the ... organized content on topics such as home care (generally) as well as senior care ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... Sweden , April 20, 2017 ... NEVPF) ("NeuroVive") today announced positive preclinical results ... preclinical compound for non-alcoholic steatohepatitis (NASH), in ... NV556 has previously shown ... NASH model. Today, NeuroVive,s scientists present novel ...
(Date:4/19/2017)... Cardiology devices segment is anticipated to reach the highest market ... segment is likely to create absolute $ opportunity of a ... By the end of 2027, Cardiology Devices segment is projected ... expanding at a CAGR of 18.4% over the forecast period. ... reprocessed medical devices market in terms of revenue ...
(Date:4/19/2017)... 19, 2017 Global Surgical Drainage Device Market: ... used to remove excess liquid and air. The fluid ... bile or lymph. Surgical drains are used in a ... orthopedics surgery, cardiovascular surgery, neurosurgery, plastic surgery etc. Common ... prevent accumulation of fluid e.g. blood or pus. Surgical ...
Breaking Medicine Technology: