Navigation Links
Endoscope with an oxygen sensor detects pancreatic cancer
Date:6/6/2014

JACKSONVILLE, Fla. June 6, 3014 An optical blood oxygen sensor attached to an endoscope is able to identify pancreatic cancer in patients via a simple lendoscopic procedure, according to researchers at Mayo Clinic in Florida.

The study, published in GIE: Gastrointestinal Endoscopy, shows that the device, which acts like the well-known clothespin-type finger clip used to measure blood oxygen in patients, has a sensitivity of 92 percent and a specificity of 86 percent.

MULTIMEDIA ALERT: Video and audio are available for download on the Mayo Clinic News Network.

That means, of 100 patients with pancreatic cancer, this sensor would detect 92 of them, based on the findings. And of 100 patients who don't have pancreatic cancer, the test would correctly identify them 86 percent of the time.

The device measures changes in blood flow in the tissues that are in the proximity to the pancreas, under the theory that tumors change the flow of blood flow in surrounding tissues because the tumors need oxygen to grow. The endoscope is passed into the stomach and the duodenum, where the measurements are taken. The pancreas lies just outside the duodenum.

"Although this is a small pilot study, the outcome is very promising. There is no test now available that can accurately identify pancreatic cancer at an early stage, short of removing some of the organ," says the study's senior investigator and gastroenterologist Michael Wallace, M.D., M.P.H. "We need new ways to detect pancreatic cancer effectively, and simply, as early as possible."

Now, more than 90 percent of pancreatic cancers are discovered at an advanced or metastatic stage with no effective therapy available. That explains why pancreatic cancer is the fourth most common cause of cancer deaths in the U.S., although it ranks 10th in occurrence.

"We are now confirming our findings in a much larger study, involving institutions in the U.S. and in Europe," Dr. Wallace says.

The technique is a very different way of looking at cancer detection, he says.

"What is quite unusual is that we were trying to sense changes that are not in the tumor itself but are in the nearby, normal-appearing tissues," he says. "It relies on a principle, now being increasingly acknowledged, called a cancer field effect. Instead of looking for the needle in the haystack, we now look at the haystack to see how it is different when there's a needle inside.

"The general concept is that cancers cause surrounding tissue to undergo changes in the flow of oxygen that are detectable, not visually or even under the microscope, but by this kind of sensor," Dr. Wallace says.

To test the ability of the sensor to recognize pancreatic cancer, researchers studied two groups one in which 14 patients were already diagnosed with the cancer, and another in 10 cancer-free patients.

Dr. Wallace says the blood sensor endoscope is also being tested in colon and esophageal cancers.


'/>"/>

Contact: Kevin Punsky
punsky.kevin@mayo.edu
904-953-0746
Mayo Clinic
Source:Eurekalert

Related medicine news :

1. The connection between oxygen and diabetes
2. Oxygen diminishes the hearts ability to regenerate, researchers discover
3. Smartphone app reads blood oxygen levels to hospital standards, advances to global obstetrics tests
4. Clinical opinion published on use of maternal oxygen during labor
5. Cell behavior in low oxygen conditions mapped
6. Portable Oxygen Concentrators: Market Shares, Strategies, and Forecasts, Worldwide, 2013 to 2018
7. Oxygen levels in tumors affect response to treatment
8. Oxygen Concentrators: Market Shares, Strategies, and Forecasts, Worldwide, 2013 to 2018
9. InventHelp® Client Develops Oxygen-Tank Accessory (JMC-1162)
10. InventHelp® Client Invention Allows For Safer Use of Oxygen Hoses (CLC-4778)
11. Considering Transplant and on Oxygen, Singer-Songwriter with Rare Lung Disease Returns to Stage Nov. 7, Pulmonary Hypertension Association Announces
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... ... ... Those who have experienced traumatic events may suffer from a complex set of ... or alcohol abuse, as a coping mechanism. To avoid this pain and suffering, Serenity ... event. , Trauma sufferers tend to feel a range of emotions, from depression, guilt, ...
(Date:6/24/2016)... ... 24, 2016 , ... Global law firm Greenberg Traurig, P.A. announced that 20 ... by their peers for this recognition are considered among the top 2 percent of ... honors as members of this year’s Legal Elite Hall of Fame: Miami Shareholders ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are sharpening ... Talker Award, an essay contest in which patients and their families pay tribute to ... at the 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this ...
(Date:6/24/2016)... ... 2016 , ... Strategic Capital Partners, LLC (SCP) in concert ... capital for emerging technology companies. SCP has delivered investment events and professional ... than a million dollars of capital investment for five companies. The ...
(Date:6/24/2016)... , ... June 24, 2016 , ... ... supporting the upcoming 2016 Miss Arizona pageant as its official Medspa Sponsor. Dr. ... Tempe, Mesa, and Chandler, Arizona. , Dr. Olson says the decision to ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 2016 Research and Markets has announced ... Analysis 2016 - Forecast to 2022" report to their ... contains up to date financial data derived from varied research ... trends with potential impact on the market during the next ... which comprises of sub markets, regional and country level analysis. ...
(Date:6/23/2016)... , June 23, 2016 Bracket , ... launch its next generation clinical outcomes platform, Bracket eCOA (SM) ... held on June 26 – 30, 2016 in ... first electronic Clinical Outcome Assessment product of its kind to ... #715. Bracket eCOA 6.0 is a flexible platform ...
(Date:6/23/2016)... NORTHBROOK, Ill. and BOGOTA, Colombia , June 23, 2016  Astellas today announced the ... joins Astellas Farma Brasil as the company,s second affiliate in Latin America . ... ... appointed General Manager of Astellas Farma Colombia ... ...
Breaking Medicine Technology: