Navigation Links
Endometrial and acute myeloid leukemia cancer genomes characterized
Date:5/1/2013

nucleotide sequence) that can affect the expression of genes. TCGA is jointly supported and managed by the National Human Genome Research Institute (NHGRI) and the National Cancer Institute (NCI), both part of the National Institutes of Health.

The findings, which appeared online May 1, 2013, in the New England Journal of Medicine set the stage for identifying potential new drug targets and treatment strategies for AML. They may also offer better guidance for predicting the severity of disease for individual patients.

"These results provide important new insights into the genomics of a deadly and difficult-to-treat cancer, and underscore the power and scope of The Cancer Genome Atlas project," said NIH Director Francis S. Collins, M.D., Ph.D.

"Rather than just random snapshots about individual patients, this study provides a more detailed look at the aberrant genomes of AML than we have ever had before," said NHGRI Director Eric D. Green, M.D., Ph.D. "It has the potential to open up new directions in AML research, and perhaps, in the design of new therapeutics, its impact could be felt in the near future."

AML, the most common acute form of adult leukemia, develops when immature white blood cells fail to mature and instead accumulate in the bone marrow. The leukemia cells reduce the production of healthy blood cells, leading to anemia, abnormal bleeding and infections, and, if untreated, death.

Researchers examined the genomes of tumor specimens from 200 adult cases of spontaneously occurring, newly diagnosed AML. These cases represented all of the known subtypes of AML in approximately the same proportion as the general population. In this way, the study provided a realistic view of the disease, particularly in the number and frequency of genomic alterations. Each AML genome was compared to the normal genome derived from a skin sample of the same patient. Out of the 200 samples, 50 were analyzed by using whole
'/>"/>

Contact: NCI Press Office
ncipressofficers@mail.nih.gov
301-496-6641
NIH/National Cancer Institute
Source:Eurekalert

Page: 1 2 3 4 5 6 7 8 9

Related medicine news :

1. Keeping Fit May Boost Survival With Endometrial Cancer
2. Childbirth After 30 Lowers Risk of Endometrial Cancer: Study
3. Women who give birth after age 30 lower their risk of endometrial cancer
4. Nephrologist follow-up improves mortality of severe acute kidney injury patients
5. Frequently used biologic agents might cause acute liver injury
6. American College of Physicians unveils tools to improve acute coronary syndrome care
7. Avamere Family of Companies Acquires Six Transitional Care Facilities, Expands Eastward into New Post-Acute Markets.
8. Acute stroke therapy used 3 times more at certified primary stroke centers
9. High-Dose Statins Linked to Acute Kidney Damage
10. Newly incarcerated have 1 percent acute hepatitis C prevalence
11. Mortality for acute aortic dissection near 1 percent per hour during initial onset
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/25/2015)... Iowa City, Iowa (PRWEB) May 25, 2015 ... Engineering Excellence awards for design of the ... in Iowa City, Iowa.    The project received a National Recognition ... and an Honor Award from ACEC – Iowa. ... outstanding engineering achievements. , The $50.2 million expansion is ...
(Date:5/25/2015)... 2015 After the sensational buzz surrounding ... human wellness company Trivedi Master Wellness™ agrees ... world-class series titled, “Consciousness is Power.” Presently, the Live-Streaming ... 2015 at the routinely allotted time from 10:00pm PST/1:00pm ... be made available to the public and accessible on ...
(Date:5/24/2015)... Kong (PRWEB) May 25, 2015 Pacific Prime has ... three part report looking at the cost of individual international ... Destinations, Article 2 looks at the cost of health insurance in ... , Focusing on, Hong Kong , ... the UAE , the UK ...
(Date:5/24/2015)... Metamora, Michigan (PRWEB) May 24, 2015 ... allow them to take pressure measurements in patients’ bladder ... The doctor usually orders it if they have reported ... (OAB). , Women’s Excellence in Bladder Control ... with unwanted urinary leakage or problems with overall control ...
(Date:5/24/2015)... 24, 2015 ProPin is a set ... Pro X. Utilize ProPin to pin point locations on a ... , ProPin allows users to choose from 30 simplistic ... With on-screen controls, video editors can easily manipulate ProPin presets ... and mark with absolute ease. , Using ProPin is easy, simply ...
Breaking Medicine News(10 mins):Health News:Stanley Consultants’ Expansion of Iowa City Wastewater Treatment Plant Wins National Award 2Health News:Stanley Consultants’ Expansion of Iowa City Wastewater Treatment Plant Wins National Award 3Health News:Hundreds of People Are Thrilled to Hear that Trivedi Master Wellness™ Promises to Hold Another Workshop in June 2015 2Health News:Hundreds of People Are Thrilled to Hear that Trivedi Master Wellness™ Promises to Hold Another Workshop in June 2015 3Health News:Pacific Prime Releases 2nd Article of Cost of Health Insurance Report 2Health News:Developers at Pixel Film Studios Release ProPin for Final Cut Pro X. 2
... ... the new trend emerging in the UK is the usage of the anti-ageing jab ... of wrinkles and lift and tighten the chest area around the breasts, leaving smoother, ... ...
... ATLANTA, Nov. 6 Recently a Narconon of Georgia graduate was ... drug abuse. The special report focused on the growing problem of ... Andrew shared his near death experience and his belief that more ... up, blinked once and the next thing I knew I opened ...
... The Leukemia & Lymphoma Society (LLS) will ... in its first two campaigns this past spring and summer, garnered ... and patient education and support services. , During the campaign, taking ... downloadable 30% discount coupons participants can use (in-store ...
... The U.S. Department of Veterans Affairs held a historic ... beginning of a new mission for the agency - ... than 1,300 VA clinicians and health care specialists, representatives ... and low-income veterans, and community- and faith-based service providers ...
... Plan International, a leading children,s development organization with offices ... to deliver eight presentations on children,s health and well-being ... Meeting & Exposition in Philadelphia, Pennsylvania on November 7-11, ... organizations together to address current and emerging health science, ...
... ... majority of physicians surveyed (74 percent) feel they have less control over the way they ... ... from Jackson Healthcare reports that the majority of physicians surveyed (74 percent) feel ...
Cached Medicine News:Health News:UK Boobs Get a Boost with 'Breastox' 2Health News:Narconon Drug Rehab of Georgia Graduate Featured on Local News 2Health News:Get a Jump on Your Holiday Shopping and Give Two Gifts This Season: One to Your Loved Ones and One to People Battling Blood Cancer 2Health News:VA Summit Frames Plan to End Veteran Homelessness 2Health News:Plan's Expertise Highlighted at Premier Health Forum 2Health News:Physicians Losing Control of Medicine: New Survey Reports Medical Malpractice as Primary Reason, 2Health News:Physicians Losing Control of Medicine: New Survey Reports Medical Malpractice as Primary Reason, 3Health News:Physicians Losing Control of Medicine: New Survey Reports Medical Malpractice as Primary Reason, 4
(Date:5/22/2015)... 2015 Research and Markets( http://www.researchandmarkets.com/research/28m7nx/guide_to_prepare ) ... to Prepare Application Dossiers for Oversea Medical device ... report to their offering. The ... market of the most growth potentiality, which is ... and producers to penetrate such market. It is ...
(Date:5/22/2015)... DUBLIN , May 22, 2015 Research ... announced the addition of the "Latest Regulations ... report to their offering. This ... officially issued a guidance on international multi-center clinical ... , which has begun to be implemented on ...
(Date:5/22/2015)...  In a sweeping analysis assessing the current state ... researchers conclude that there remains considerable room for ... age groups, but especially for adolescents and young adults. ... treatment, underscoring the need to address barriers to care ... type 1 patients achieve optimal metabolic control. ...
Breaking Medicine Technology:China Guide to Prepare Application Dossiers for Oversea Medical Device Registration and Recordation 2China Guide to Prepare Application Dossiers for Oversea Medical Device Registration and Recordation 32015 Regulations on Pharmaceutical International Multi-Center Clinical Trials in China 2Study Reveals Poor Disease Control Among Adolescents and Young Adults with Type 1 Diabetes 2Study Reveals Poor Disease Control Among Adolescents and Young Adults with Type 1 Diabetes 3Study Reveals Poor Disease Control Among Adolescents and Young Adults with Type 1 Diabetes 4Study Reveals Poor Disease Control Among Adolescents and Young Adults with Type 1 Diabetes 5
... 2011 Henry Schein, Inc., (NASDAQ: HSIC ), ... office-based practitioners, announced today that Stanley M. Bergman, ... Paladino, the Company,s Executive Vice President and Chief Financial Officer, ... Conference on May 4, 2011. The conference is being held ...
... Pharmaceuticals, Inc. (NYSE: WPI ) today ... launched an authorized generic version of Concerta® (methylphenidate ... agreement with Ortho-McNeil-Janssen Pharmaceuticals, Inc. (OMJPI).  Watson began ... the treatment of attention deficit hyperactivity disorder (ADHD) ...
Cached Medicine Technology:Henry Schein to Present at Deutsche Bank 36th Annual Health Care Conference 2Watson Launches Generic Concerta® 2Watson Launches Generic Concerta® 3
The Thermal pads were designed to simulate water immersion, the most effective method of transferring energy non-invasively....
This blanket is ideal for warming the large child or small adult during upper body surgery....
The fabric is antistatic and non-linting and is both oil and water repellent.These superior blankets are an environmental friendly alternative to disposable blankets....
The fabric is antistatic and non-linting and is both oil and water repellent.These superior blankets are an environmental friendly alternative to disposable blankets....
Medicine Products: