Navigation Links
Endocare Announces That National Cancer Institute to Sponsor Study Comparing Cryoablation to Radiation Therapy for Pain Relief in Bone Cancer Patients
Date:11/27/2007

Cryoablation And Radiation Effectiveness (CARE) for Bone Pain to Measure

Quality of Life, Complication Rates in Prospective, Randomized,

Multi-Center Study

IRVINE, Calif., Nov. 27 /PRNewswire-FirstCall/ -- Endocare, Inc. (Nasdaq: ENDO), an innovative medical device company focused on the development of minimally invasive technologies used by urologists and interventional radiologists for tissue and tumor ablation, announced today that the National Cancer Institute (NCI) of the National Institutes of Health (NIH) is supporting a multi-center study comparing the pain-reducing palliative effects of cryoablation and radiation therapy for patients who are experiencing focal pain from cancer that has metastasized to their bones. The prospective, randomized study, called Cryoablation And Radiation Effectiveness (CARE) for Bone Pain and led by interventional radiologist Matthew Callstrom, M.D., PhD, of Mayo Clinic, will evaluate the efficacy of percutaneous cryoablation compared to external beam radiation therapy (RT) as measured by pain relief, quality of life, analgesic use and complication rates. Dr. Callstrom is also leading another multi-center study on cryoablation of painful metastatic disease.

The trial will be open to patients nationwide through the NCI oncology group network and conducted by the North Central Cancer Treatment Group.

A total of 128 patients are expected to take part in the study. Percutaneous cryoablation is a minimally invasive procedure in which tumors are targeted with ultrasound, computed tomography or magnetic resonance imaging guidance and treated by freezing. This destroys or ablates the tumor. The Endocare Cryocare(R) System will be used to treat all patients in the cryoablation arm of the study. Endocare will also contribute to the funding of the study.

Endocare Chief Executive Officer, President and Chairman Craig T. Davenport noted that the bone is the most common site of metastases, or the spread of cancer, and that many patients do not get adequate pain relief from conventional treatments including chemotherapy, radiation or other drug therapies. There are estimates that more than 100,000 people worldwide suffer from painful bone metastases.

"This is a very important study for Endocare but also for the thousands of patients who are suffering from the spread of cancer to the bone and who have very few viable options to relieve the pain it causes while retaining an active lifestyle," Davenport added. "If the results of the study turn out the way that the early data demonstrate they should, we will have a significant new pain-relieving alternative for cancer patients."

Davenport also noted that Endocare already has clearance from the U.S. Food and Drug Administration to ablate tumors and tissue throughout the body, including this percutaneous cryoablation for palliation of painful metastatic lesions. It is hoped that the study will demonstrate that cryoablation is effective in bone cancer and this could be important to gain positive reimbursement decisions from both government and private payers, Davenport said.

About the NCCTG

The North Central Cancer Treatment Group (NCCTG) is a national clinical research group sponsored by the National Cancer Institute. NCCTG consists of a network of cancer specialists at community clinics, hospitals and medical centers in the United States, Canada and Mexico. The research and administrative base for NCCTG is located at Mayo Clinic in Rochester, Minn. NCCTG is dedicated to bringing clinical trials with promising new cancer therapies to communities where patients live. NCCTG specializes in researching methods of treating and preventing cancer, and in researching methods to alleviate the side effects of cancer and cancer treatments.

About NCI

The National Cancer Institute (NCI), part of the National Institutes of Health in Bethesda, Maryland, coordinates the Nation's research program on cancer prevention, detection, diagnosis, treatment, rehabilitation, and control. NCI was established by Congress in 1937, and its programs were intensified in 1971 after passage of new legislation called the National Cancer Act. As a result of the 1971 legislation, the NCI has built a network that includes regional and community cancer centers, physicians who are cancer specialists, cooperative groups of clinical researchers, and volunteer and community outreach groups. NCI also has initiated cancer control programs to hasten the application of knowledge gained through cancer research.

About Endocare

Endocare, Inc. -- http://www.endocare.com -- is an innovative medical device company focused on the development of minimally invasive technologies for tissue and tumor ablation. Endocare has initially concentrated on developing technologies for the treatment of prostate cancer and believes that its proprietary technologies have broad applications across a number of markets, including the ablation of tumors in the kidney, lung and liver and palliative intervention (treatment of pain associated with metastases).

Statements contained in this release that are not historical facts are forward-looking statements that involve risks and uncertainties. Among the important factors which could cause actual results to differ materially from those in the forward-looking statements include, but are not limited to, those discussed in "Risk Factors" in the Company's Forms 10-K, Forms 10-Q, and other filings with the Securities and Exchange Commission. Such risk factors include, but are not limited to, uncertainty regarding the ultimate results of the study described in this press release and uncertainty regarding the ability to gain positive reimbursement decisions from government and private payers. The actual results that the Company achieves may differ materially from any forward-looking statements due to such risks and uncertainties. The Company undertakes no obligation to revise, or update publicly, any forward-looking statements for any reason.

Investor Contact: Media Contact: For Additional Information:

Matt Clawson Len Hall Craig T. Davenport, CEO

Allen & Caron, Inc. Allen & Caron, Inc. Michael R. Rodriguez, CFO

(949) 474-4300 (949) 474-4300 Endocare, Inc.

matt@allencaron.com len@allencaron.com (949) 450-5400


'/>"/>
SOURCE Endocare, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Related medicine news :

1. Endocare Stock to Commence Trading on NASDAQ
2. Endocare Reports 2007 Third Quarter and Nine-Month Results
3. HHS Announces $75 Million in Supplemental Funding to States for Pandemic Flu Preparedness
4. CRC Health Group Announces Acquisition of Bayside Marin Recovery Center, San Rafael
5. UHW Announces: Antelope Valley Hospital Caregivers and Board Vote to Ratify First Union Contract With SEIU UHW-West
6. HEI, Inc. Announces Sale of RFID Division Assets
7. Caraco Pharmaceutical Laboratories, Ltd. Announces FDA Approval to Market Generic Version of Zyloprim(R)
8. Mettler-Toledo International Inc. Announces Webcast of Presentation at Thomas Weisel Partners 2007 Healthcare Conference
9. Z Trim Announces Revocation of Gregory Halpern Severence Agreement
10. Brooke Franchise Corporation Announces Selected July Results
11. Manor Care, Inc. Announces Record Date for Special Stockholder Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/25/2016)... (PRWEB) , ... May 25, 2016 , ... ... Institute (WCRI) compare outcomes of injured workers across 15 states. The outcomes ... work, earnings recovery, access to medical care, and satisfaction with medical care. , ...
(Date:5/25/2016)... Culver City, California (PRWEB) , ... May 25, ... ... a new interest group ADDMI - “Advancing Drug Development through Molecular Imaging.” The ... address some of the current drug discovery and development pipeline issues. Through ADDMI-IG ...
(Date:5/25/2016)... ... ... Afrimesure specializes in providing clients with ideal measurement and ... facilities. Their knowledgeable staff also takes care of the installation, IQ/OQ/PQ qualification protocols, ... variety of MadgeTech systems available for sterilization and temperature monitoring, including the software ...
(Date:5/25/2016)... ... 25, 2016 , ... The University of San Francisco (USF) has named Margaret ... a team of more than 100 full-time faculty and staff, and serve as a ... late August. , Baker comes to USF from the University of Washington in Seattle, ...
(Date:5/25/2016)... ... May 25, 2016 , ... "FCPX LUT Intense allows users to cycle through ... Austin - CEO of Pixel Film Studios. , With the FCPX LUT Intense ... color grades to their footage. A LUT is a Lookup Table that contains a ...
Breaking Medicine News(10 mins):
(Date:5/25/2016)... MedDay, a biotechnology company focused on ... presentation entitled "High doses of biotin in progressive multiple sclerosis: ... by Professor Ayman Tourbah , Principal Investigator of the ... Academy of Neurology (EAN) in Copenhagen, Denmark ... take place on Sunday, 29 May 2016 from 14:45 to ...
(Date:5/24/2016)... Cirujanos holandeses han puesto en marcha una ... compartir sus mejores prácticas por el mundo y tratar ... Europa, África, Asia y Estados ... combina la transmisión en vivo con mensajería instantánea y ... "Imagine un médico de Medicines sans Frontieres ...
(Date:5/24/2016)... -- ARANZ Medical  Ltd a specialist in ... been named the Coretex Hi-Tech Emerging Company of the Year ... Bruce Davey , CEO of ARANZ Medical says, "This ... to be recognised for the work we are doing to ... 35 countries around the world from Sub-Saharan Africa through to ...
Breaking Medicine Technology: