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Endocare Announces That National Cancer Institute to Sponsor Study Comparing Cryoablation to Radiation Therapy for Pain Relief in Bone Cancer Patients
Date:11/27/2007

Cryoablation And Radiation Effectiveness (CARE) for Bone Pain to Measure

Quality of Life, Complication Rates in Prospective, Randomized,

Multi-Center Study

IRVINE, Calif., Nov. 27 /PRNewswire-FirstCall/ -- Endocare, Inc. (Nasdaq: ENDO), an innovative medical device company focused on the development of minimally invasive technologies used by urologists and interventional radiologists for tissue and tumor ablation, announced today that the National Cancer Institute (NCI) of the National Institutes of Health (NIH) is supporting a multi-center study comparing the pain-reducing palliative effects of cryoablation and radiation therapy for patients who are experiencing focal pain from cancer that has metastasized to their bones. The prospective, randomized study, called Cryoablation And Radiation Effectiveness (CARE) for Bone Pain and led by interventional radiologist Matthew Callstrom, M.D., PhD, of Mayo Clinic, will evaluate the efficacy of percutaneous cryoablation compared to external beam radiation therapy (RT) as measured by pain relief, quality of life, analgesic use and complication rates. Dr. Callstrom is also leading another multi-center study on cryoablation of painful metastatic disease.

The trial will be open to patients nationwide through the NCI oncology group network and conducted by the North Central Cancer Treatment Group.

A total of 128 patients are expected to take part in the study. Percutaneous cryoablation is a minimally invasive procedure in which tumors are targeted with ultrasound, computed tomography or magnetic resonance imaging guidance and treated by freezing. This destroys or ablates the tumor. The Endocare Cryocare(R) System will be us
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SOURCE Endocare, Inc.
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